The Chemistry of Carboxylic Acids and Esters
Author : Saul Patai
Publisher :
Page : 1178 pages
File Size : 48,23 MB
Release : 1969
Category : Science
ISBN :
Author : Saul Patai
Publisher :
Page : 1178 pages
File Size : 48,23 MB
Release : 1969
Category : Science
ISBN :
Author : Marc Harrold
Publisher : ASHP
Page : 405 pages
File Size : 38,60 MB
Release : 2013-01-18
Category : Medical
ISBN : 1585283649
Medicinal chemistry is a complex topic. Written in an easy to follow and conversational style, Basic Concepts in Medicinal Chemistry focuses on the fundamental concepts that govern the discipline of medicinal chemistry as well as how and why these concepts are essential to therapeutic decisions. The book emphasizes functional group analysis and the basics of drug structure evaluation. In a systematic fashion, learn how to identify and evaluate the functional groups that comprise the structure of a drug molecule and their influences on solubility, absorption, acid/base character, binding interactions, and stereochemical orientation. Relevant Phase I and Phase II metabolic transformations are also discussed for each functional group. Key features include: • Discussions on the roles and characteristics of organic functional groups, including the identification of acidic and basic functional groups. • How to solve problems involving pH, pKa, and ionization; salts and solubility; drug binding interactions; stereochemistry; and drug metabolism. • Numerous examples and expanded discussions for complex concepts. • Therapeutic examples that link the importance of medicinal chemistry to pharmacy and healthcare practice. • An overview of structure activity relationships (SARs) and concepts that govern drug design. • Review questions and practice problems at the end of each chapter that allow readers to test their understanding, with the answers provided in an appendix. Whether you are just starting your education toward a career in a healthcare field or need to brush up on your organic chemistry concepts, this book is here to help you navigate medicinal chemistry. About the Authors Marc W. Harrold, BS, Pharm, PhD, is Professor of Medicinal Chemistry at the Mylan School of Pharmacy, Duquesne University, Pittsburgh, PA. Professor Harrold is the 2011 winner of the Omicron Delta Kappa "Teacher of the Year" award at Duquesne University. He is also the two-time winner of the "TOPS" (Teacher of the Pharmacy School) award at the Mylan School of Pharmacy. Robin M. Zavod, PhD, is Associate Professor for Pharmaceutical Sciences at the Chicago College of Pharmacy, Midwestern University, Downers Grove, IL, where she was awarded the 2012 Outstanding Faculty of the Year award. Professor Zavod also serves on the adjunct faculty for Elmhurst College and the Illinois Institute of Technology. She currently serves as Editor-in-Chief of the journal Currents in Pharmacy Teaching and Learning.
Author : Stephen Y. Lin
Publisher : Springer Science & Business Media
Page : 595 pages
File Size : 42,36 MB
Release : 2012-12-06
Category : Technology & Engineering
ISBN : 3642740650
An up-to-date compilation of the theoretical background and practical procedures involved in lignin characterization. Whenever possible, the procedures are presented in sufficient detail to enable the reader to perform the analysis solely by following the step-by-step description. The advantages and limitations of individual methods are discussed and, more importantly, illustrated by typical analytical data in comparison to results obtained from other methods. This handbook serves the need of researchers and other professionals in academia, the pulp and paper industry as well as allied industries. It is equally useful for those with no previous experience in lignin or lignocellulosics.
Author : R. D. Tiwari
Publisher : Elsevier
Page : 141 pages
File Size : 50,55 MB
Release : 2013-10-22
Category : Science
ISBN : 1483151255
Monographs in Organic Functional Group Analysis, Volume 3: Determination of Carboxylic Functional Groups focuses on the quantitative determination of acid chlorides, esters, carboxylic acids, anhydrides, lactones, and amides. The monograph first takes a look at the determination of carboxylic acids. Countercurrent and electrophoretic separation of organic acids; polarography of organic acids; acid-base equilibrium in non-aqueous media; and titrimetric determination of acids are discussed. The book also examines the determination of acid anhydrides, chlorides, and esters. The characteristics and composition of acid chlorides and anhydrides, as well as the saponification and spectroscopic methods used in the identification of esters, are presented. The book also evaluates the methods and use of Grignard's reagent in the determination of amides. The text also presents an analysis of binary and ternary mixtures. Mixtures of acids and acid chlorides, differentiation of acids, mixtures of acids and esters, and mixtures of acids and amides are discussed. The monograph is a vital reference for readers interested in the quantitative determination of acid chlorides, esters, carboxylic acids, and other related compounds.
Author : Bruce Averill
Publisher :
Page : 1233 pages
File Size : 22,52 MB
Release : 2007
Category : Chemistry
ISBN : 9780321413703
Emphasises on contemporary applications and an intuitive problem-solving approach that helps students discover the exciting potential of chemical science. This book incorporates fresh applications from the three major areas of modern research: materials, environmental chemistry, and biological science.
Author : SONIA RATNANI
Publisher : PHI Learning Pvt. Ltd.
Page : 309 pages
File Size : 19,48 MB
Release : 2012-06-12
Category : Science
ISBN : 8120346130
Primarily intended for the undergraduate students of science, the book deals with the practical aspects of organic chemistry and discusses how experiments should be done in the laboratory. The book introduces the various types of components used in laboratories and describes basic techniques used for purification. It elaborates different methods of identification of organic compounds, their preparation, and analysis. In addition, it emphasizes qualitative analysis of organic compounds. The book contains essential experiments done in an organic lab and also explains the theoretical background of reactions involved. This book is an attempt to provide students with the often used methods in an easy to understand manner, including explanations of theory, procedures and interpretations of results of the experiments. Besides undergraduate students of science, this book is also useful for the postgraduate students of chemistry. KEY FEATURES : Includes reaction mechanism of each reaction Describes in Appendices safety measures to be taken in laboratory and how to prepare chemical reagents Contains self assessment questions at the end of each chapter.
Author : Brian C. Smith
Publisher : CRC Press
Page : 286 pages
File Size : 45,76 MB
Release : 1998-12-10
Category : Science
ISBN : 9780849324635
This author's second volume introduces basic principles of interpreting infrared spectral data, teaching its readers to make sense of the data coming from an infrared spectrometer. Contents include spectra and diagnostic bands for the more common functional groups as well as chapters on polyester spectra and interpretation aids. Discussions include: Science of infrared interpretation Light and molecular vibrations How and why molecules absorb infrared radiation Peak heights, intensities, and widths Hydrocarbons, carbonyl groups, and molecules with C-N bonds Polymers and inorganic molecules The use of atlases, library searching, spectral subtraction, and the Internet in augmenting interpretation Each chapter presents an introduction to the nomenclature and structure of a specific functional group and proceeds with the important diagnostic bands for each group. Infrared Spectral Interpretation serves both novices and experienced practitioners in this field. The author maintains a website and blog with supplemental material. His training course schedule is also available online.
Author : Hrvoj Vančik
Publisher : Springer Nature
Page : 213 pages
File Size : 13,16 MB
Release : 2022-01-18
Category : Medical
ISBN : 3030924386
This textbook is designed for students of biology, molecular biology, ecology,medicine, agriculture, forestry and other professions where the knowledge of organic chemistry plays an important role. The work may also be of interest to non-professionals, as well as to teachers in high schools. The book consists of 13 chapters that cover the essentials of organic chemistry, including - basic principles of structure and constitution of organic compounds, - the elements of the nomenclature, - the concepts of the nature of chemical bond, - introductions in NMR and IR spectroscopy, - the concepts and main classes of the organic reaction mechanisms, - reactions and properties of common classes or organic compounds, - and the introduction to the chemistry of the natural organic products followed by basic principles of the reactions in living cells. This second edition includes revisions and suggestions made by the readers of the first edition and the author's colleagues. In addition, it includes substantial changes compared to the first edition. The chapter on Cycloaddition has been completed by including the other pericyclic reactions (sigmatropic rearrangements, electrocyclic reactions). The chapter on Organic Natural Products has been extended to include new section covering the principles of organic synthesis. New chapter "Organic Supramolecular and Supermolecular Structures" is added. This chapter covers the basic knowledge about the molecular recognition, supramolecular structures, and the mechanisms of the enzyme catalyzed reactions.
Author : Georgiana-Ileana Badea
Publisher : BoD – Books on Demand
Page : 96 pages
File Size : 19,77 MB
Release : 2018-06-13
Category : Science
ISBN : 1789232783
This book is an attempt to bring together current knowledge on the role and importance of organic acids in life processes. There are lots of compounds based on the chemical nature of this functional group, which makes this class of molecules to be present in our lives starting with the human body (Krebs cycle - the core of cellular metabolism) to the products we currently use (food, medicines and cosmetics). No overall consensus is sought in this book, and the following chapters are authored by dedicated researchers presenting a diversity of applications and hypotheses concerning organic acids. The five chapters in this book include general information on carboxylic acids and their applications in life sciences (use in organic synthesis, nanotechnology, plant physiology, plant nutrition and soil chemistry).
Author : V.K. Ahluwalia
Publisher : Universities Press
Page : 308 pages
File Size : 31,78 MB
Release : 2004-06
Category :
ISBN : 9788173714283
This manual for practical qualitative analysis covers the use of spectroscopic methods for identification of various functional groups, Comprehensive tables giving methods for the systematic identification of pure specimens, separation of mixtures and compounds, and procedures for preparation of derivatives are some of the salient features of the book.