Reducing Environmental Cancer Risk


Book Description

Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.




How Tobacco Smoke Causes Disease


Book Description

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.







Carcinogens and Anticarcinogens in the Human Diet


Book Description

Despite increasing knowledge of human nutrition, the dietary contribution to cancer remains a troubling question. Carcinogens and Anticarcinogens assembles the best available information on the magnitude of potential cancer riskâ€"and potential anticarcinogenic effectâ€"from naturally occurring chemicals compared with risk from synthetic chemical constituents. The committee draws important conclusions about diet and cancer, including the carcinogenic role of excess calories and fat, the anticarcinogenic benefit of fiber and other substances, and the impact of food additive regulation. The book offers recommendations for epidemiological and diet research. Carcinogens and Anticarcinogens provides a readable overview of issues and addresses critical questions: Does diet contribute to an appreciable proportion of human cancer? Are there significant interactions between carcinogens and anticarcinogens in the diet? The volume discusses the mechanisms of carcinogenic and anticarcinogenic properties and considers whether techniques used to evaluate the carcinogenic potential of synthetics can be used with naturally occurring chemicals. The committee provides criteria for prioritizing the vast number of substances that need to be tested. Carcinogens and Anticarcinogens clarifies the issues and sets the direction for further investigations into diet and cancer. This volume will be of interest to anyone involved in food and health issues: policymakers, regulators, researchers, nutrition professionals, and health advocates.




Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water


Book Description

This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.




Handbook of Disability, Work and Health


Book Description

This work presents a summary of research evidence on links between work, health and disability. Across two sections it summarizes updated knowledge on adverse effects of distinct occupational hazards, and it covers concerns with employment opportunities or restrictions. The handbook delivers an overview of material and psychosocial factors as occupational hazards on working people’s physical or mental health that may result in functional impairment and disability. This knowledge can be instrumental in strengthening efforts of professionals and other stakeholders to promote health-conducive working conditions and prevent work-related disability risks. It also covers concerns with employment opportunities or restrictions of persons with physical or mental health problems and disability. This field of interdisciplinary research has grown with a broad range of solid new findings that can have favorable impact on work disability prevention and the practice of medical and vocational rehabilitation. Prominent experts discuss this evidence for major manifestations of physical and mental health problems and disabilities. As a further innovative feature, this handbook integrates biomedical, psychological, and sociological knowledge on major aspects of the links between work, health and disability. It is therefore of interest to students and professionals in related disciplines, as well as for stakeholders involved in the prevention of work disability and rehabilitation into paid work. In times of an increasingly aging work force with elevated risks of reduced health and work functioning, this knowledge can contribute to turning the threats associated with disability into opportunities. This handbook supports the overall aim of enabling persons with (chronic) health problems and disability to participate in work and social life.




Outdoor Air Pollution


Book Description

"This publication represents the views and expert opinions of an IARC Working Group on the Evaluation of Carcinogenic Risk to Humans, which met in Lyon, 8-15 October 2013."




Comparative Oncology


Book Description




Diet Nutrition And Cancer


Book Description

This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work is in the "public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.




Diet, Nutrition, and Cancer


Book Description