The Lymphatic Continuum


Book Description

This interdisciplinary volume brings together many of the world's leading biomedical investigators to discuss current and anticipated developments in lymphatic biology and pathology and in related areas, including vasculogenesis and angiogenesis, the genetics of lymphatic disorders, muscle cell biology, interstitial signaling mechanisms, and others.




Immunology of the Lymphatic System


Book Description

This book will be a comprehensive study of the lymphatic system and its immunological role. It will begin with lymphatic capillaries, their origin and development. It will treat lymph circulation, in general, with a special emphasis on lymph circulation in parenchymal organs. The next section will address lymph nodes, subcortical circulation and the conduit system. It will discuss organs with no lymphatic system, such as the brain. Finally, it will cover lymph composition and cells in the lymph. While primarily basic research, the volume will touch upon elements of the clinical, as well, broadening its scope and appeal.​




Capillary Fluid Exchange


Book Description

The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascular smooth muscle tone in arterioles, hydraulic conductivity in capillaries, and neutrophil transmigration across postcapillary venules, while the flow of this filtrate through the interstitial spaces functions to modify the activities of parenchymal, resident tissue, and metastasizing tumor cells. Likewise, the flow of lymph, which is driven by capillary filtration, is important for the transport of immune and tumor cells, antigen delivery to lymph nodes, and for return of filtered fluid and extravasated proteins to the blood. Given this background, the aims of this treatise are to summarize our current understanding of the factors involved in the regulation of transcapillary fluid movement, how fluid movements across the endothelial barrier and through the interstitium and lymphatic vessels influence cell function and behavior, and the pathophysiology of edema formation. Table of Contents: Fluid Movement Across the Endothelial Barrier / The Interstitium / The Lymphatic Vasculature / Pathophysiology of Edema Formation




Lymphedema


Book Description

The second edition of this book serves as a central source of theoretical and practical knowledge to optimize the evaluation and treatment of patients with lymphedema. The book covers all aspects of the disease from anatomical and histological features to diagnosis as well as physical/medical and surgical management of the disease. Updated from the first edition to reflect the substantial progress in diagnostics, medical care and surgical intervention for this patient population, this volume has been reorganized to meet today’s practice requirements. It addresses the challenges faced by clinicians in the management of chronic lymphedema enabling them to meet the medical needs of this large patient community. Edited by world leaders in Vascular Medicine and Surgery, this comprehensive volume provides clear, concise background and recommendations in an easy-to-use format. It is a valuable reference tool for clinical practitioners (physicians/nurse practitioners/technicians) who wish to deliver state-of-the-art health care to their patients with lymphatic and venous disorders.




Textbook of Vascular Medicine


Book Description

This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.




The Book of Lymph


Book Description

A first-of-its-kind guide that outlines and explains the health-promoting properties of lymphatic massage, featuring beautifully illustrated, five-minute self-massage sequences anyone can do at home. Thanks to the astonishing results it provides—glowing skin, a flatter stomach, enhanced immunity, and full-body detox—the practice of manually stimulating the lymphatic system has become one of the most popular wellness practices today. Lymphatic drainage works because the lymphatic system—a complex geography of rivers that snake throughout the body just beneath the surface of the skin—connects every other bodily system. When lymph flows, everything else flows, too. In this first-of-its-kind guide, veteran lymphatic drainage practitioner, educator, and advocate Lisa Levitt Gainsley explains how to maintain lymphatic health, sharing the five-minute self-massage techniques she originally developed for her high-powered Los Angeles clientele. These simple sequences are tailored to address a number of specific and common issues: bloating, headaches, digestive problems, immune health, anxiety, weight loss, acne, inflammation, and more. Whether you just want to look and feel your best or are facing a more serious health issue such as cancer treatment or recovery, The Book of Lymph offers educational and practical instruction to help you cultivate a body free of pain and lethargy, activate a calmer state of being, and boost overall glow—in just five minutes a day.




The Cardiac Lymphatic System


Book Description

The heart is invested with a complex, intertwining network of blood and lymphatic vessels which, respectively, provide the cardiac tissue with oxygen and nutrients and eliminate excess fluid from the interstitium. The coronary blood vessels have been the focus of much investigation in the past few decades. On the other hand, the literature regarding the cardiac lymphatic vessels remains sparse, despite their important role in maintaining normal heart function. With this in mind, a better understanding of the cardiac lymphatic network and its ability to regulate fluid homeostasis within the heart could give us insight into developing therapies for the alleviation of several cardiac pathological conditions.




The Anatomy of the Lymphatic System


Book Description

Reprint of the original, first published in 1873.




Manual of Vascular Diseases


Book Description

Knowledge and understanding of vascular disease, particularly atherosclerosis, continue to expand across disciplines, as do diagnostic and therapeutic strategies for treatment of vascular disorders. This manual offers a consistent "how to" approach that places specific emphasis on management. Each chapter provides the reader with a highly practical approach so that he or she comes away with a reasonable amount of familiarity as to be able to manage the patient independently. Since the first edition, a certification in vascular medicine has become available. Some of the key features include: • Practical information such as drug doses, protocols for managing disorders, and algorithms; • Guidance on diagnostic assessment and treatment strategies for the majority of vascular disorders encountered in clinical practice; • Assimilation of information from areas outside cardiology, i.e., vascular surgeons and interventional radiologists, into a reader-friendly format geared toward the average practicing internist or cardiologist.




Integrative Therapies in Rehabilitation


Book Description

For more than 20 years, Integrative Therapies in Rehabilitation continues to be a most researched resource on complementary and alternative therapies in rehabilitation. This renowned text, now in its Fourth Edition, relates the updated scientific evidence and the clinical efficacy of integrating what have now become well known complementary and alternative therapies in rehabilitation to successfully improve patient outcomes. This text has been developed to accompany university courses in complementary and alternative therapies, as a reference manual for clinical practices, and as a resource for those interested in the science behind holistic therapies. Holistic therapies are those therapies not commonly found in allopathic medicine that are intended to stimulate a therapeutic response from both the body – neuromusculoskeletal and cardiopulmonary systems – and the mind. Integrative Therapies in Rehabilitation, Fourth Edition by Dr. Carol M. Davis is particularly designed for those health professionals who want to understand the scientific foundation and peer reviewed research supporting complementary and alternative therapies. The Fourth Edition is divided into two parts. The beginning chapters describe the latest cellular biology science and explain the theories put forth on the overall mechanisms of action of the effect of these various therapies on the soft tissue, fascia and nervous systems. The first part also chronicles the advancement of scientific research in the various therapies since the 1980’s to explain, in cellular physiology terms, the outcomes observed by using a number of holistic therapies. The second part presents various therapies commonly integrated with allopathic therapies in rehabilitation – body work therapies, mind/body therapies, and energy work therapies. The text describes each therapy with a history, cellular mechanism of action, and an up-dated reference section of the evidence of efficacy for the therapy as reported in the literature, often concluding with a case example. Integrative Therapies in Rehabilitation, Fourth Edition will be the go-to resource for health professionals to understand the scientific evidence and efficacy of complementary and alternative therapies for rehabilitation and improving patient outcomes.