The Militant Genome


Book Description

A master gene for race? Geneticists say such a thing doesn't exist. However, the Colonel, founder of the Missouri White Alliance, has devised a genetic weapon capable of devastating dark-skinned peoples globally. He is only weeks, maybe days away from implementing his viral version of racial cleansing's "final solution." There's only one threat to his plan -- a hotheaded member of the MWA has become the target of a nationwide police search for murder and the kidnapping of local celebrity Della Winston ... and the unwanted attention risks bringing federal scrutiny to the previously unknown white supremacy group. Sarah Wade, MD, has enough stress as a senior Emergency Medicine resident. She never expected that her discovery of a murdered medical student would inadvertently jeopardize her career. Or that the next-day murder of a Nigerian diplomat would lead to the kidnapping of her best friend, Della Winston. The cascade of events pull her -- and Seamus O'Connor, the detective assigned to the high-profile medical center murder -- into a life-threatening conspiracy of murder, kidnapping, and rising racial tensions. The Militant Genome is a medical thriller set is St. Louis. Woven into the story are themes about the evil of racism, the threats of biotechnology, and one's eternal destiny. The story begins as Sarah Wade, MD, a senior resident in Emergency Medicine, takes her Advanced Trauma Life Support credentialing course and discovers that her surrogate patient, a medical student, is a real stabbing victim. Sgt. Seamus O'Connor and his partner draw the case and begin their investigation. Within twenty-four hours, Sarah's life is turned inside out -- her career is threatened by false charges from the pompous, egotistical Chief of Trauma; a visiting Nigerian diplomat is murdered outside a popular restaurant on the riverfront; and the only witness to see the killer's face, Sarah's life-long best friend, Della Winston, is kidnapped outside a local club. Meanwhile, from across the country, the events in St. Louis are being followed with concern by the Colonel. He is part of a university medical research team presenting their work on Alzheimer's Disease to a major symposium. During the day, he has helped discover a major breakthrough in the cause and potential treatment of the disease. Outside the lab, he leads a previously unknown white supremacy group, the Missouri White Alliance, based in the Ozarks. With his like-minded technicians, they have found a way to re-engineer a promising treatment for the skin cancer melanoma into a viral weapon that attacks dark-skinned peoples. By combining that virus with a virulent strain of influenza, he hopes to cause worldwide racial genocide to honor his grandfather, a Klu Klux Klan Grand Wizard during his life, and to avenge the murders of his wife and daughter at the hands of black home invaders. However, he has received word that the man who killed the diplomat is not just one of his men but his nephew. The intense police and federal investigation into that killing threatens to unveil his group and derail his plans. The story explores the issue of racism not just via the major plot line about racial genocide, but also through the unexpected relationship that develops between Sarah and Seamus. She is African-American and he is as white and Irish as they come. They have their Catholic backgrounds as common ground, but nothing more. The potential threat of biotechnology in the wrong hands should be apparent. The definition of genome is "a full set of chromosomes; all the inheritable traits of an organism." The genome is God's blueprint for life. Leave it to man's "tinkering" to lead to trouble. The theme of eternal destiny becomes an important turning point in the story. Let's not spoil it by giving away anything more.




Editing the Soul


Book Description

Personal genome testing, gene editing for life-threatening diseases, synthetic life: once the stuff of science fiction, twentieth- and twenty-first-century advancements blur the lines between scientific narrative and scientific fact. This examination of bioengineering in popular and literary culture shows that the influence of science on science fiction is more reciprocal than we might expect. Looking closely at the work of Margaret Atwood, Richard Powers, and other authors, as well as at film, comics, and serial television such as Orphan Black, Everett Hamner shows how the genome age is transforming both the most commercial and the most sophisticated stories we tell about the core of human personhood. As sublime technologies garner public awareness beyond the genre fiction shelves, they inspire new literary categories like “slipstream” and shape new definitions of the human, the animal, the natural, and the artificial. In turn, what we learn of bioengineering via popular and literary culture prepares the way for its official adoption or restriction—and for additional representations. By imagining the connections between emergent gene testing and editing capacities and long-standing conversations about freedom and determinism, these stories help build a cultural zeitgeist with a sharper, more balanced vision of predisposed agency. A compelling exploration of the interrelationships among science, popular culture, and self, Editing the Soul sheds vital light on what the genome age means to us, and what’s to come.




The Social Life of DNA


Book Description

The unexpected story of how genetic testing is affecting race in America We know DNA is a master key that unlocks medical and forensic secrets, but its genealogical life is both revelatory and endlessly fascinating. Tracing genealogy is now the second-most popular hobby amongst Americans, as well as the second-most visited online category. This billion-dollar industry has spawned popular television shows, websites, and Internet communities, and a booming heritage tourism circuit. The tsunami of interest in genetic ancestry tracing from the African American community has been especially overwhelming. In The Social Life of DNA, Alondra Nelson takes us on an unprecedented journey into how the double helix has wound its way into the heart of the most urgent contemporary social issues around race. For over a decade, Nelson has deeply studied this phenomenon. Artfully weaving together keenly observed interactions with root-seekers alongside illuminating historical details and revealing personal narrative, she shows that genetic genealogy is a new tool for addressing old and enduring issues. In The Social Life of DNA, she explains how these cutting-edge DNA-based techniques are being used in myriad ways, including grappling with the unfinished business of slavery: to foster reconciliation, to establish ties with African ancestral homelands, to rethink and sometimes alter citizenship, and to make legal claims for slavery reparations specifically based on ancestry. Nelson incisively shows that DNA is a portal to the past that yields insight for the present and future, shining a light on social traumas and historical injustices that still resonate today. Science can be a crucial ally to activism to spur social change and transform twenty-first-century racial politics. But Nelson warns her readers to be discerning: for the social repair we seek can't be found in even the most sophisticated science. Engrossing and highly original, The Social Life of DNA is a must-read for anyone interested in race, science, history and how our reckoning with the past may help us to chart a more just course for tomorrow.




The Myth of Junk DNA


Book Description

According to the modern version of Darwin's theory, DNA contains a program for embryo development that is passed down from generation to generation; the program is implemented by proteins encoded by the DNA, and accidental DNA mutations introduce changes in those proteins that natural selection then shapes into new species, organs and body plans. When scientists discovered forty years ago that about 98% of our DNA does not encode proteins, the non-protein-coding portion was labeled “junk” and attributed to molecular accidents that have accumulated in the course of evolution. Recent books by Richard Dawkins, Francis Collins and others have used this “junk DNA” as evidence for Darwinian evolution and evidence against intelligent design (since an intelligent designer would presumably not have filled our genome with so much garbage). But recent genome evidence shows that much of our non-protein-coding DNA performs essential biological functions. The Myth of Junk DNA is written for a general audience by biologist Jonathan Wells, author of Icons of Evolution. Citing some of the abundant evidence from recent genome projects, the book shows that “junk DNA” is not science, but myth.




The Selfish Gene


Book Description

The million copy international bestseller, critically acclaimed and translated into over 25 languages. As influential today as when it was first published, The Selfish Gene has become a classic exposition of evolutionary thought. Professor Dawkins articulates a gene's eye view of evolution - a view giving centre stage to these persistent units of information, and in which organisms can be seen as vehicles for their replication. This imaginative, powerful, and stylistically brilliant work not only brought the insights of Neo-Darwinism to a wide audience, but galvanized the biology community, generating much debate and stimulating whole new areas of research. Forty years later, its insights remain as relevant today as on the day it was published. This 40th anniversary edition includes a new epilogue from the author discussing the continuing relevance of these ideas in evolutionary biology today, as well as the original prefaces and foreword, and extracts from early reviews. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.




Hearings


Book Description




The Missing Gene


Book Description

Researchers still haven't found the genes that underlie schizophrenia, bipolar disorder, ADHD, and autism; perhaps they do not exist. A genetic researcher in psychiatry and psychology urges we return our focus to family, social, and political environments as the sources of psychological distress.




Genomics in Biosecurity


Book Description

Genomics in Biosecurity: Principles and Applications of Genomic Technologies in Expanded Biosecurity Concepts, in the Translational and Applied Genomics series, explains in definite and practical terms the applicability of genomic technologies in every aspect of biosecurity, from emergent diagnostics to bioterrorism, agroterrorism, next generation biowarfare, biosurveillance and risk assessment. This book offers an integrated discussion of genomics and GCBR (global catastrophic biological risks) events, considering both basic aspects of biosecurity genomics and application of genomic technologies to drive new solutions. Readers will find evidence-based strategies to apply genomics in disease and pathogen monitoring and diagnosis, and more. Social aspects of GCBR events and genomic biosecurity, such as issues of terrorism, policy ethics, and practice, are also considered in-depth. - Examines the use of genomics in pathogen monitoring and diagnosis, biosurveillance, and countermeasures for spontaneous and perpetrated events - Discusses social, ethical, and policy aspects of GCBR events and the use of genomic technologies in biosecurity - Empowers new solutions in biorestoration, biocrime, counterbioterrorism, disaster management, and humanitarian crisis response - Features chapter contributions from a range of international specialists




From Biotechnology To Genomes: The Meaning Of The Double Helix


Book Description

Aimed at scientists and non-specialised readers alike, this book retraces the source of national and international biotechnology programmes by examining the origins of biotechnology and its political and economic interpretation by large nations. With a foreword by André Goffeau, who initiated the European Yeast Genome Project, the book describes the achievements of the first genetic and physical maps, as well as the political and scientific genesis of the American Human Genome Project. Following these advances, the author discusses the European biotechnology strategy, the birth and implementation of European biotechnology programmes and the yeast genome project. After a detailed description of scientific policy and administrative, technical and scientific achievements, the principal stages of the yeast project and its major benefits are discussed. This enables the reader to obtain a panoramic view of this developing discipline at the dawn of the twenty-first century, as well as a better knowledge of the means deployed at international level. The conclusion gives a very detailed account of the genesis and early stages of this new scientific and technological field called genomics which appears to be a key component of modern industry. By using an epistemological analysis, the conclusion poses the problem of a new representation of life and critically appraises the limitations and deficiencies.




From Darwinian Metaphysics Towards Understanding the Evolution of Evolutionary Mechanisms


Book Description

"Although Charles Darwin predicted that his theory 'would give zest to ... metaphysics, ' even he would be astonished at the variety of paths his theory has in fact taken. This holds with regard to both gene-Darwinism, a purified Darwinian approach biologizing the social sciences, and process- Darwinism found in the disciplines of psychology, philosophy of science, and economics. Although Darwinism is often linked to highly confirmed biological theories, some of its interpretations seem to profit from tautological claims as well, where scientific reputation cloaks ideological usage. This book discusses central tenets of Darwinism historically as well as systematically, for example the history of different Darwinian paradigms, the units-of-selection debate, and the philosophical problem of induction as basis of metaphysical Darwinism. Crucially the book addresses the Darwinian claim that evolution is governed by an immutable and unrelentingly cruel law of natural selection. Paradoxically, Darwins theory is a static, non-evolutionary theory of evolution. The current book sketches the historical background and provides suggestions that may help to replace this approach by the idea of an evolution of evolutionary mechanisms (see Escher's 'Drawing Hands' on the cover). This view even suggests a tendency to overcome the blindness of the knowledge acquisition of primordial Darwinian processes and allows for some freedom from external environments. This book first develops a radically Darwinian approach, then criticises this approach from within. Even Darwinism has a tendency to transcend itself. Although the book addresses several empirical issues, it does not challenge particular findings. Instead it builds on many insights of Darwinism and provides a proposal for interpreting known empirical evidence in a different light. It should help pave the way for further developing an understanding of nature that transcends Darwinian metaphysics"--Publisher's description.