The Neurobiological Basis of Memory and Behavior


Book Description

Of all the areas of biological science, there is, perhaps, none that has experienced in recent decades so great an increase in findings as neurobiology, the discipline that concerns memory in all of its myriad aspects. The notion of exploring memory, that capacity to store and recall individual experience, has received attention increasingly in our society. Of course, animals can exhibit astounding powers of memory, but memory is of paramount importance to human beings due to the significant role it plays in the transmission of our cultural traditions. It is tradition, after all, that ensures the passing on of qualities established by lineage, a continuous link from generation to generation, between past and present. And it is tradition that inspires bodies of thought (knowledge and customs, for example) to be handed down by a multiplicity of information bearing devices (i. e. , word, writing, picture, electronic data carriers). The objective of this book is to inform the reader in one clear volume of the groundwork which has been established in memory research from the diverse disciplines of neurobiology. It is intended, primarily, for students of medicine, zoology, biology, psychology and psychiatry, but will certainly prove to be a valuable resource to others with a healthy interest in the area.




Discovering the Brain


Book Description

The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."




The Neurobiological Basis of Memory


Book Description

This exciting volume offers an up-to-date tour of current trends in the neurobiology of memory while saluting Raymond Kesner's pioneering contributions to the field as a theorist and researcher, teacher and mentor. Starting with his signature chapter introducing the Attribute Model of Memory, the first half of the book focuses on the central role of the hippocampus in processing dimensions of space and time, and branches out to memory system interactions across brain structures. Later chapters apply the attribute model to multiple functions of memory in learning, and to specific neurological contexts, including Huntington's disease, traumatic brain injury, and Fragile X. As a bonus, the book concludes with an essay on Kesner's life and work, and reminiscences by colleagues. Among the topics covered: How the hippocampus supports the spatial and temporal attributes of memory. Self-regulation of memory processing centers of the brain. Multiple memory systems: the role of Kesner's Attribute Model in understanding the neurobiology of memory. Pattern separation: a key processing deficit associated with aging? · Prefrontal cortex and basal ganglia attributes underlying behavioral flexibility. Memory disruption following traumatic brain injury. Cognitive neuroscientists, neuropsychologists, gerontologists, psychiatrists, and neurobiologists will find The Neurobiological Basis of Memory both enlightening and inspiring--much like Kesner himself.




The Development of Memory in Infancy and Childhood


Book Description

The Development of Memory in Infancy and Childhood provides a thorough update and expansion of the previous edition and offers new research on significant themes and ideas that have emerged in the past decade such as the cognitive neuroscience of memory development, autobiographical memory and infantile amnesia, and the cognitive and social factors that underlie memory for events. In this volume, Courage and Cowan bring together leading international experts to review the current state of the science of memory development in their own research areas. They note questions of theory and basic science addressed in their research, highlight the real-world applications of those findings, and propose an agenda for future research. The book also considers the implications of their work for the development of atypical children, specifically, how these new findings might be adapted to enrich the lives of those children and to inform and validate our current expectations of individual differences in the development of typical children. The first of three groups of chapters focuses on basic neurobiological, perceptual, and cognitive processes that underlie memory and its development (i.e., encoding, consolidation and storage, retrieval). The second group focuses primarily on the social, contextual, and cultural factors that enable, shape, and mediate these basic processes, while the rest of the chapters focus on practical applications of this knowledge to real-world settings and issues. The book provides a new look at memory development, including new topics such as spatial representation and spatial working, prospective memory, false memories, and memory and culture. This classic yet contemporary volume will appeal to senior undergraduate and graduate students of developmental and cognitive psychology, as well as to developmental psychologists who want a compendium of key topics in memory development.




Behavioral Neuroscience of Learning and Memory


Book Description

‘Behavioral Neuroscience of Learning and Memory’ brings together the opinions and expertise of some of the world’s foremost neuroscientists in the field of learning and memory research. The volume provides a broad coverage of contemporary research and thinking in this field, focusing both on well established topics such as the medial temporal lobe memory system, as well as emerging areas of research such as the role of memory in decision making and the mechanisms of perceptual learning. Key intersecting themes include the molecular and cellular mechanisms of memory formation, the multiplicity of memory systems in the brain, and the way in which technological innovation is driving discovery. Unusually for a volume of this kind, this volume brings together research from both humans and animals—often relatively separate areas of discourse—to give a more comprehensive and integrated view of the field. The book will be of interest to both established researchers who wish to broaden their knowledge of topics outside of their specific areas of expertise, and for students who need a resource to help them make sense of the vast scientific literature on this subject.




Identification of Neural Markers Accompanying Memory


Book Description

Identification of Neural Markers Accompanying Memory is a fresh and novel volume of memory study, providing up-to-date and comprehensive information for both students and researchers focused on the identification of neural markers accompanying memory. Contributions by experts in specific areas of memory study provide background on and definitions of memory, memory alterations, and the brain areas involved in memory and its related processes, such as consolidation, retrieval, forgetting, amnesia, and antiamnesiac effects. With coverage of the principal neurotransmitters related to memory, brain disorders presenting memory alterations, and available treatments—and with discussion of neural markers as new targets for the treatment of memory alterations—Identification of Neural Markers Accompanying Memory is a necessary and timely work for researchers in this growing field. Discusses the alterations of memory in diverse diseases Includes coverage from a basic introduction of memory investigation Reviews brain areas and neurotransmitters involved in memory Discusses behavioral models of memory Contains novel insights into the complexity of signaling and memory Includes the neuropharmacological and neurobiological bases of memory




Neurobiology of Learning and Memory


Book Description

The first edition of Neurobiology of Learning and Memory was published in 1998 to rave reviews. As before, this second edition will discuss anatomy, development, systems, and models though the organization and content is substantially changed reflecting advances in the field. Including information from both animal and human studies, this book represents an up-to-date review of the most important concepts associated with the basic mechanism that support learning and memory, theoretical developments, use of computational models, and application to real world problems. The emphasis of each chapter will be the presentation of cutting-edge research on the topic, the development of a theoretical perspective, and providing an outline that will aid a student in understanding the most important concepts presented in the chapter. *New material covers basal ganglia, cerebellum, prefrontal cortex, and fear conditioning*Additional information available on applied issues (i.e., degenerative disease, aging, and enhancement of memory)*Each chapter includes an outline to assist student understanding of challenging concepts*Four-color illustrations throughout




Psychobiology of Posttraumatic Stress Disorder


Book Description

Less than twenty years ago the field of mental health did not have the language to describe the long-term consequences of traumatic stress. In the absence of specific biological markers, the psychological symptoms of trauma survivors were often attributed to neurotic or even psychotic disorders. But in 1980, after more than a century of clinical observations, post-traumatic stress disorder (PTSD) was recognized as a diagnosis. By the 1990s, biological findings began to provide objective validation that PTSD is more than a politically or socially motivated conceptualization of human suffering. This volume summarizes the latest findings in this rapidly changing field, including the biological differences between PTSD, stress, and other psychiatric disorders Chief among the findings is that PTSD is a different disorder than was originally thought, and that the biology of PTSD is not simply the biology of stress. Topics include the empirical basis for post-traumatic stress disorder; psychobiological findings; neurodevelopmental effects of trauma; neurological basis of traumatic and non-traumatic memory impairment in post-traumatic stress disorder; how basic research informs clinical observations; and the psychobiology of treatment.




Learning and Memory


Book Description

Learning and Memory presents a comprehensive, up-to-date overview of brain*b1behavior relations as they bear on learning and memory. The structure of memory is investigated from a diversity of approaches, including anatomical, pharmacological, electrophysiological and lesions, and through the use of different populations, such as invertebrate, vertebrate, and human. Features updated chapters, including a new chapter on human cognitive processes and amnesia Presents multiple views of memory Examines a diversity of levels of analysis, methods of approach, and theoretical perspectives




The Physiological Basis of Memory


Book Description

The Physiological Basis of Memory, Second Edition reviews many areas of research that shed light on the physiological basis of memory, from mnemonic function and memory facilitation to synaptic transmission. The book also considers neuropsychology involving animal subjects, learning produced by direct brain stimulation, and the basis of associative learning at the cellular level. This edition is organized into 10 chapters and begins with an overview of the link between protein synthesis and memory, paying attention to studies devoted to chemical changes associated with learning; the effect of inhibitors of RNA and protein synthesis on learning; the molecular code of memory; and the role of proteins in learning. The reader is methodically introduced to the enhancement of memory consolidation; the use of the cellular-connection approach to investigate both non-associative and associative learning; and the effect of depression on memory storage. The following chapters discuss the impact of brain lesions on animal memory; the neurology of memory and amnesia in human and nonhuman primates; the function of the neural substrate for self-stimulation of the medial forebrain bundle; and the effects of electroconvulsive shock on memory. A chapter on the role of catecholamines in memory processing concludes the book. This book should be useful to researchers and students interested in the physiology of memory.