EU REACH Enforcement project


Book Description







Advanced Manufacturing. An ICT and Systems Perspective


Book Description

Manufacturing plays a vital role in European economy and society, and is expected to continue as a major generator of wealth in the foreseeable future. A competitive manufacturing industry is essential for the prosperity of Europe, especially in the face of accelerating deindustrialisation. This book provides a broad vision of the future of manufac




Registries for Evaluating Patient Outcomes


Book Description

This User’s Guide is intended to support the design, implementation, analysis, interpretation, and quality evaluation of registries created to increase understanding of patient outcomes. For the purposes of this guide, a patient registry is an organized system that uses observational study methods to collect uniform data (clinical and other) to evaluate specified outcomes for a population defined by a particular disease, condition, or exposure, and that serves one or more predetermined scientific, clinical, or policy purposes. A registry database is a file (or files) derived from the registry. Although registries can serve many purposes, this guide focuses on registries created for one or more of the following purposes: to describe the natural history of disease, to determine clinical effectiveness or cost-effectiveness of health care products and services, to measure or monitor safety and harm, and/or to measure quality of care. Registries are classified according to how their populations are defined. For example, product registries include patients who have been exposed to biopharmaceutical products or medical devices. Health services registries consist of patients who have had a common procedure, clinical encounter, or hospitalization. Disease or condition registries are defined by patients having the same diagnosis, such as cystic fibrosis or heart failure. The User’s Guide was created by researchers affiliated with AHRQ’s Effective Health Care Program, particularly those who participated in AHRQ’s DEcIDE (Developing Evidence to Inform Decisions About Effectiveness) program. Chapters were subject to multiple internal and external independent reviews.




OECD Series on Testing and Assessment International Best Practices for Identification of Priorities within Chemicals Management Systems


Book Description

This document captures and examines schemes used internationally for prioritising chemicals for risk assessment and/or risk management, and identifies commonalities, differences, lessons learned and areas for improvement. Based on this analysis it offers guiding principles and best practices to consider within prioritisation schemes.







Per and polyfluorinated substances in the Nordic Countries


Book Description

This Tema Nord report presents a study based on open information and custom market research to review the most common perfluorinated substances (PFC) with less focus on PFOS and PFOA. The study includes three major parts:1) Identification of relevant per-and polyfluorinated substances and their use in various industrial sectors in the Nordic market by interviews with major players and database information; 2) Emissions to and occurence in the Nordic environment of the substances described in 1); 3) A summary of knowledge of the toxic effects on humans and the environment of substances prioritized in 2); There is a lack of physical chemical data, analystical reference substances, human and environmental occurrence and toxicology data, as well as market information regarding PFCs other than PFOA and PFOS and the current legislation cannot enforce disclosure of specific PFC substance information.




Toxic Substances in Articles


Book Description

The use of toxic chemicals in articles is a growing concern for public health and the environment. International trade results in substances being transported among regions. From toys and household items to electronic equipment and automobiles, toxic substances in articles are an increasingly important factor contributing to the global burden of toxic substances. Toxic substances in articles may pose threats at every stage of the product life cycle - production, use, and disposal or recycling. In this report, we consider a factor that is critical for the sound management of substances in articles: the availability of information. At present, there is no global system for provision of information about substances in a wide range of articles. First, the report describes the problem of toxic substances in articles, with detailed case studies of selected examples and considers the advantages that would result from better information management systems. Second, the report considers existing efforts to generate and disseminate information about substances in articles, both regulatory requirements and voluntary initiatives. Third, the report offers suggestions as to the questions and themes that would need to be considered in order to improve management of information about substances in articles.




Building Continents of Knowledge in Oceans of Data: The Future of Co-Created EHealth


Book Description

The domain of eHealth faces ongoing challenges to deliver 21st century healthcare. Digitalization, capacity building and user engagement with truly interdisciplinary and cross-domain collaboration are just a few of the areas which must be addressed. This book presents 190 full papers from the Medical Informatics Europe (MIE 2018) conference, held in Gothenburg, Sweden, in April 2018. The MIE conferences aim to enable close interaction and networking between an international audience of academics, health professionals, patients and industry partners. The title of this year’s conference is: Building Continents of Knowledge in Oceans of Data – The Future of Co-Created eHealth, and contributions cover a broad range of topics related to the digitalization of healthcare, citizen participation, data science, and changing health systems, addressed from the perspectives of citizens, patients and their families, healthcare professionals, service providers, developers and policy makers. The second part of the title in particular has attracted a large number of papers describing strategies to create, evaluate, adjust or deliver tools and services for improvements in healthcare organizations or to enable citizens to respond to the challenges of dealing with health systems. Papers are grouped under the headings: standards and interoperability, implementation and evaluation, knowledge management, decision support, modeling and analytics, health informatics education and learning systems, and patient-centered services. Attention is also given to development for sustainable use, educational strategies and workforce development, and the book will be of interest to both developers and practitioners of healthcare services.