Author : Antonio Tito Fojo
Publisher : Springer Science & Business Media
Page : 629 pages
File Size : 36,35 MB
Release : 2009-01-14
Category : Medical
ISBN : 1597453366
This book presents the first comprehensive exploration of the dynamic potential of microtubules anti-cancer targets. Written by leading anti-cancer researchers, this groundbreaking volume collects the most current microtubule research available and investigates the potential of microtubules in cancer therapy.
Author : Maria Kavallaris
Publisher : Springer Science & Business Media
Page : 463 pages
File Size : 31,51 MB
Release : 2012-04-23
Category : Science
ISBN : 161779788X
The cytoskeleton is comprised of a variety of specialized proteins, and is a dynamic structure that is involved in the majority of key cellular events. There is increasing interest in the role of the cytoskeleton in human disease. This volume brings together human disease states where cytoskeletal disruptions are driving disease. Our emerging understanding of the molecular and cellular events that drive cytoskeletal mediated diseases including cancer, heart disease, myopathies and skin disorders, are also helping shape targeted therapeutic approaches to treating these diseases.
Author : Ludovica Monti
Publisher : Sapienza Università Editrice
Page : 354 pages
File Size : 25,60 MB
Release : 2022-11-30
Category : Medical
ISBN : 8893772426
Microtubules are essential cellular constituents of eukaryotes formed by tubulin subunits. This book is a collection of medicinal chemistry research projects that utilizes microtubules as drug targets for human diseases of global health impact. The main chapters (2 – 4) include an in-depth description of different synthetic and biological approaches to characterize the therapeutic potential of novel synthetic molecules for cancer, Alzheimer’s disease, and neglected tropical diseases. This book also includes three short chapters (5 – 7) of additional collaborative projects focused on varied drug discovery topics, including SAR studies of new lead compounds targeting carbonic anhydrase enzymes, FAAH and TRPV1, and novel bioisosteres of the carboxylic acid functional group.
Author : John J. Correia
Publisher : Academic Press
Page : 472 pages
File Size : 35,33 MB
Release : 2013-08-20
Category : Science
ISBN : 0124078885
There continues to be intense interest in the microtubule cytoskeleton; the assembly, structure and regulation of microtubules; and the numerous motors and accessory proteins that control cell cycle, dynamics, organization and transport. The field continues to grow and explore new aspects of these issues driven immensely by developments in optical imaging and tracking techniques. This Second Edition brings together current research and protocols in the field of microtubules in vitro and will serve as a valuable tool for cell biologists, biophysicists and pharmacologists who study the microtubule cytoskeleton, as well as for researchers in the biomedical and biotechnology communities with interest in developing drugs that target microtubules, MAPS and motors. - Chapters reflect experimental procedures and new developments in the field of microtubule in vitro research - Combines classical approaches and modern technologies - Presents easy-to-use protocols and thorough background information, compiled by leaders in the field
Author : Graham A. Colditz
Publisher : SAGE Publications
Page : 1631 pages
File Size : 46,80 MB
Release : 2015-08-12
Category : Health & Fitness
ISBN : 1483345742
The first edition of the Encyclopedia of Cancer and Society was published in 2007 and received a 2008 Editors’ Choice Award from Booklist. It served as a general, non-technical resource focusing on cancer from the perspective of the social and behavioral sciences, exploring social and economic impacts, the “business” of cancer, advertising of drugs and treatment centers, how behavior change could offer great potential for cancer prevention, environmental risks, food additives and regulation, the relation between race and ethnicity and cancer risk, socioeconomic status, controversies—both scientific and political—in cancer treatment and research, country-by-country entries on cancer around the world, and more. Given various developments in the field including new drug treatments, political controversies over use of the vaccines Gardasil and Cervarix with young girls to prevent cervical cancer, and unexpected upticks in the prevalence of adult smoking within the U.S. following decades of decline, the SAGE Encyclopedia of Cancer and Society, Second Edition serves as an updated and more current encyclopedia that addresses concerns pertaining to this topic. Key Features: · Approximately half of the 700 first-edition articles revised and updated · 30+ new entries covering new developments since 2006 · Signed entries with cross-references · Further Readings accompanied by pedagogical elements · New Reader’s Guide · Updated Chronology, Resource Guide, Glossary, and through new Index The SAGE Encyclopedia of Cancer and Society, Second Edition serves as a reliable and precise source for students and researchers with an interest in social and behavioral sciences and seeks to better understand the continuously evolving subject matter of cancer and society.
Author : Maxim Ryadnov
Publisher : Royal Society of Chemistry
Page : 120 pages
File Size : 36,61 MB
Release : 2024-02-02
Category : Science
ISBN : 1839169338
Amino Acids, Peptides and Proteins is a broad ranging title comprising a selection of comprehensive and critical reviews of significant developments at the biology and chemistry interface. Compiled by leading researchers in their subject, this volume incorporates current trends and emerging areas reflecting the state-of-the-art research in this field. Appealing broadly to researchers in academia and industry, it will be of great benefit to any researcher wanting a succinct reference in this field and looking at the future.
Author : Rafael Trindade Maia
Publisher : BoD – Books on Demand
Page : 147 pages
File Size : 37,44 MB
Release : 2021-03-10
Category : Science
ISBN : 1839628057
Homology modeling is an extremely useful and versatile technique that is gaining more and more space and demand in research in computational and theoretical biology. This book, “Homology Molecular Modeling - Perspectives and Applications”, brings together unpublished chapters on this technique. In this book, 7 chapters are intimately related to the theme of molecular modeling, carefully selected and edited for academic and scientific readers. It is an indispensable read for anyone interested in the areas of bioinformatics and computational biology. Divided into 4 sections, the reader will have a didactic and comprehensive view of the theme, with updated and relevant concepts on the subject. This book was organized from researchers to researchers with the aim of spreading the fascinating area of molecular modeling by homology.
Author : Jeffrey Moore
Publisher : Frontiers Media SA
Page : 173 pages
File Size : 28,58 MB
Release : 2023-04-25
Category : Science
ISBN : 2832521452
Author : Maxim Ryadnov
Publisher : Royal Society of Chemistry
Page : 130 pages
File Size : 34,4 MB
Release : 2024-02-02
Category : Science
ISBN : 183916705X
Author : Cliff K.K. Lun
Publisher : Word Alive Press
Page : 259 pages
File Size : 50,31 MB
Release : 2022-08-31
Category : Religion
ISBN : 1486622445
Life is full of big questions. Who am I? Why am I here? Where am I going? Where do the universe, earth, and humans come from? Do humans have free will? What is the meaning of life and death? Do humans and animals have souls and spirits? Where do good and evil come from? Who is Satan? What was his original offense? Why does the devil tempt humans? Why is there pain and suffering? Can the nefarious attitudes in human spirits change for the better? Before the Beginning to Beyond the End clearly presents answers to the above questions based in Scripture. The book seeks to unpack the creation of the world and its implications for mankind through the lens of the Bible. Furthermore, it expounds on the cause for human’s fall, God’s redemption plan, Jesus’s fulfillment of Messianic prophecies, future events in the world, and what will happen to us beyond the end of time.
