The Serpin Family in the Cardiovascular System
Author : Marie-Christine Bouton
Publisher : Frontiers Media SA
Page : 166 pages
File Size : 16,29 MB
Release : 2022-03-03
Category : Medical
ISBN : 2889745724
Immune and Autoimmune Mechanisms in Cardiovascular Disease
Author : Dennis Wolf
Publisher : Frontiers Media SA
Page : 234 pages
File Size : 46,93 MB
Release : 2023-02-08
Category : Medical
ISBN : 2832514030
Book Description
Diabetes and Cardiovascular Disease
Author : Michael Johnstone
Publisher : Springer Nature
Page : 1071 pages
File Size : 11,37 MB
Release : 2023-06-01
Category : Medical
ISBN : 3031131770
Book Description
This third edition of the book offers an up-to-date review of Diabetes Mellitus with a focus on both Micro- and Macrovascular Disease. The text includes a review of the basic concepts of : Diabetes and Vascular Disease, including Endothelial Dysfunction; The Effect of Insulin on the Vascular System; The Mechanism of Atherosclerosis in Diabetes Mellitus and the Role of Inflammation on the Vascular Tree; and The Role of the Renin-Angiotensin-Aldosteronism on Diabetes Mellitus. Chapters will discuss the Genetics of Type 2 Diabetes Mellitus as well as the Metabolic Syndrome. Other chapters discuss the Risk Factors of Diabetes and Vascular Disease, including Hypertension; Dyslipidemia; and Thrombosis. The book also reviews Microcirculation; Diabetic Nephropathy; Diabetic Retinopathy; as well as the Epidemiology, Diagnosis, and Treatment of Peripheral Vascular Disease; Diabetes and Coronary Artery Disease; Diabetes and Percutaneous Interventions; Diabetes and Cardiac Surgery; and Diabetes and Heart Failure. Chapters conclude with a review of the present-day Treatment of the Diabetic Patient. Diabetes and Cardiovascular Disease, 3rd Edition, offers practicing physicians a cutting-edge scientific and clinical review of diabetic cardiovascular disease, providing both a deeper understanding of its pathology and all the day-to-day practical knowledge needed to treat patients effectively.
Diabetes and Cardiovascular Disease
Author : Michael T. Johnstone
Publisher : Springer Science & Business Media
Page : 645 pages
File Size : 18,65 MB
Release : 2007-10-28
Category : Medical
ISBN : 1592599087
Book Description
The cause of diabetes mellitus is metabolic in origin. However, its major clinical manifestations, which result in most of the morbidity and mortality, are a result of its vascular pathology. In fact, the American Heart Association has recently stated that, “from the point of view of cardiovascular medicine, it may be appropriate to say, diabetes is a cardiovascular disease” (1). But diabetic vascular disease is not limited to just the macrovasculature. Diabetes mellitus also affects the microcirculation with devastating results, including nephropathy, neuropathy, and retinopathy. Diabetic nephropathy is the leading cause of end-stage renal disease in the United States, while diabetic retinopathy is the leading cause of new-onset blindness in working-age Americans. The importance of this text on Diabetes and Cardiovascular Disease is evident by the magnitude of the population affected by diabetes mellitus. Over 10 million Americans have been diagnosed with diabetes mellitus, while another 5 million remain undiagnosed. The impact from a public health perspective is huge and increasing. As the population of the United States grows older, more sedentary, and obese, the risk of developing diabetes and its complications will increase. Epidemiological studies have identified diabetes mellitus as a major independent risk factor for cardiovascular disease. Over 65% of patients with diabetes mellitus die from a cardiovascular cause. The prognosis of patients with diabetes mellitus who develop overt clinical cardiovascular disease is much worse than those cardiovascular patients free of diabetes mellitus.
Antithrombotic Drug Therapy in Cardiovascular Disease
Author : Arman T. Askari
Publisher : Springer Science & Business Media
Page : 463 pages
File Size : 22,86 MB
Release : 2010-03-20
Category : Medical
ISBN : 1603272356
Book Description
Substantial morbidity and mortality remains associated with thrombotic events has stimulated the rapid expansion of the available armamentarium to combat pathologic thrombosis. Pathologic thrombosis plays an essential role in the pathogenesis of acute coronary syndromes (ACS), ischemic complications of percutaneous coronary intervention (PCI), venous thromboembolic disease, and embolic complications of arrhythmias and various cardiomyopathies. Written by experts in the field, Antithrombotic Drug Therapy in Cardiovascular Disease carefully examines individual and various combinations of the available antithrombotic regimens including fibrinolytic agents, antiplatelet therapies (aspirin, thieneopyridines, glycoprotein IIb/IIIa inhibitors), and anticoagulant therapies (unfractionated heparin, low-molecular-weight heparins, direct thrombin inhibitors, and synthetic factor X inhibitors), non-ST-segment elevation (NSTE) ACS and ST-segment elevation myocardial infarction (STEMI). A detailed overview, Antithrombotic Drug Therapy in Cardiovascular Disease presents the evidence demonstrating the efficacy of available antithrombotic therapies in specific disease states such as atrial fibrillation, cardiomyopathy, valvular heart disease, and heparin-induced thrombocytopenia (HIT).
The Serpin Family
Author : Margarethe Geiger
Publisher : Springer
Page : 333 pages
File Size : 18,81 MB
Release : 2015-11-13
Category : Science
ISBN : 3319227114
Book Description
The book provides an comprehensive overview on biology, genetics and cellular functions of serpins (serine protease inhibitors) in health and disease. With over 1000 members serpins are the most diverse family of protease inhibitors. Latest groundbreaking research findings are presented and broaden the understanding on inhibitory and non-inhibitory serpins, not only in mammalian organisms but also in insects, worms, plants and viruses.
Vascular Medicine: A Companion to Braunwald's Heart Disease E-Book
Author : Mark Creager
Publisher : Elsevier Health Sciences
Page : 963 pages
File Size : 28,86 MB
Release : 2019-05-22
Category : Medical
ISBN : 0323636012
Book Description
With authoritative coverage of everything from recent discoveries in the field of vascular biology to recent clinical trials and evidence-based treatment strategies, Vascular Medicine, 3rd Edition, is your go-to resource for improving your patients' cardiovascular health. Part of the Braunwald family of renowned cardiology references, this updated volume integrates a contemporary understanding of vascular biology with a thorough review of clinical vascular diseases, making it an ideal reference for vascular medicine specialists, general cardiologists, interventional cardiologists, vascular surgeons, and interventional radiologists. - Incorporates technologic advances in vascular imaging – including ultrasound, MRI, CTA, and catheter-based angiography – along with more than 230 new figures, providing an up-to-date and complete view of the vascular system and vascular diseases. - Covers novel antithrombotic therapies for peripheral artery disease and venous thromboemboism, advances in endovascular interventions for aortic aneurysms, and today's best surgical treatments for vascular diseases. - Includes seven new chapters: Pathobiology of Aortic Aneurysms; Pathobiology and Assessment of Cardiovascular Fibrosis; Large Vessel Vasculitis; Medium and Small Vessel Vasculitis; Epidemiology and Prognosis of Venous Thromboembolic Disease; Fibromuscular Dysplasia; and Dermatologic Manifestations of Vascular Disease. - Discusses methods for aggressive patient management and disease prevention to ensure minimal risk of further cardiovascular problems. - Keeps you current with ACC/AHA and ECC guidelines and the best ways to implement them in clinical practice. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
Chemistry and Biology of Serpins
Author : Frank C. Church
Publisher : Springer Science & Business Media
Page : 363 pages
File Size : 35,50 MB
Release : 2012-12-06
Category : Science
ISBN : 1461553911
Book Description
Proceedings of an International Symposium held in Chapel Hill, North Carolina, April 13-16, 1996
Cardiovascular Endocrinology and Metabolism
Author : Andrew J. Krentz
Publisher : Academic Press
Page : 531 pages
File Size : 26,27 MB
Release : 2023-03-28
Category : Medical
ISBN : 0323983189
Book Description
Cardiovascular Endocrinology and Metabolism: Theory and Practice of Cardiometabolic Medicine discusses the close intersection between metabolic disorders and cardiovascular disease, covering the basic science and pathophysiology of disease and the latest research in pharmacological approaches and translational therapeutic options. This book is a valuable resource for the vascular and endocrinology clinical and research communities in need of knowledge and potential outcomes. The global increase in the prevalence of cardiometabolic disorders, and the introduction of therapeutic options for treating metabolic disease that also lower cardiovascular risk, is bringing endocrinologists and cardiologists together in a shared clinical experience. - Discusses the intersection between metabolic disorders and cardiovascular diseases - Provides a comprehensive understanding of the relevant pathophysiology of diseases as a basis for the evidence-based management of cardiometabolic disorders - Offers a comprehensive reference, ranging from basic science and pathophysiology to clinical diagnostics and management
Rodak's Hematology
Author : Elaine M. Keohane
Publisher : Elsevier Health Sciences
Page : 917 pages
File Size : 34,25 MB
Release : 2015-02-20
Category : Medical
ISBN : 0323239064
Book Description
Featuring hundreds of full-color photomicrographs, Rodak's Hematology: Clinical Principles and Applications, 5th Edition prepares you for a job in the clinical lab by exploring the essential aspects of hematology. It shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This text also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Clinical lab experts Elaine Keohane, Larry Smith, and Jeanine Walenga also cover key topics such as working in a hematology lab, the parts and functions of the cell, and laboratory testing of blood cells and body fluid cells. Instructions for lab procedures include sources of possible errors along with comments. Case studies in each chapter provide opportunities to apply hematology concepts to real-life scenarios. Hematology instruments are described, compared, and contrasted. UPDATED, full-color illustrations make it easier to visualize hematology concepts and show what you'll encounter in the lab, with images appearing near their mentions in the text so you don't have to flip pages back and forth. Hematology/hemostasis reference ranges are listed on the inside front and back covers for quick reference. A bulleted summary makes it easy to review the important points in every chapter. Learning objectives begin each chapter and indicate what you should achieve, with review questions appearing at the end. A glossary of key terms makes it easy to find and learn definitions. NEW coverage of hematogones in the chapter on pediatric and geriatric hematology helps you identify these cells, a skill that is useful in diagnosing some pediatric leukemias. UPDATED chapter on molecular diagnostics covers new technology and techniques used in the lab.
