Molecular Biology of the Cell
Author :
Publisher :
Page : 0 pages
File Size : 35,49 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Author :
Publisher :
Page : 0 pages
File Size : 35,49 MB
Release : 2002
Category : Cells
ISBN : 9780815332183
Author : John W. B. Hershey
Publisher :
Page : 0 pages
File Size : 46,90 MB
Release : 1996
Category : Genetic regulation
ISBN : 9780879694586
A comprehensive account of recent research in translational control and the molecular mechanisms involved, focusing on the numerous control mechanisms observed in eukaryotes. Subjects include basic mechanisms; the role of phosphorylation; regulation by trans-acting proteins; effects of viral infection; and mRNA stability. Other topics include translational control mediated by upstream AUG codons; a comparative view of initiation site selection mechanisms; and genetics of mitochondrial translation. For researchers with interests in gene expression, RNA biology, and protein synthesis. Annotation copyright by Book News, Inc., Portland, OR
Author : Gary Hime
Publisher : Springer Science & Business Media
Page : 370 pages
File Size : 20,54 MB
Release : 2013-05-22
Category : Medical
ISBN : 9400766211
This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes – achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic – (1) illustrating the general principles outlined above through a series of different stem cell examples – embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.
Author :
Publisher : Academic Press
Page : 993 pages
File Size : 33,91 MB
Release : 2013-05-06
Category : Science
ISBN : 0123973481
The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 1 offers 48 high level articles devoted mainly to patterning and cell type specification in the developing central and peripheral nervous systems. - Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components develop - Features leading experts in various subfields as Section Editors and article Authors - All articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarship - Volume 1 sections include coverage of mechanisms which: control regional specification, regulate proliferation of neuronal progenitors and control differentiation and survival of specific neuronal subtypes, and controlling development of non-neural cells
Author : Isabelle Godin
Publisher : Springer Science & Business Media
Page : 188 pages
File Size : 31,80 MB
Release : 2010-05-27
Category : Medical
ISBN : 0387335358
This book collects articles on the biology of hematopoietic stem cells during embryonic development, reporting on fly, fish, avian and mammalian models. The text invites a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing conserved trends in development. The book reviews current knowledge on human hematopoietic development and discusses recent breakthroughs of relevance to both researchers and clinicians.
Author : James D. Adams
Publisher : Royal Society of Chemistry
Page : 319 pages
File Size : 17,35 MB
Release : 2011
Category : Medical
ISBN : 1849731608
Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are just as important but have been largely ignored in other works. Aimed at medical professionals and pharmaceutical specialists, this book integrates extracellular and intracellular signalling processes and offers a fresh perspective on new drug targets.
Author : Carlos Simón
Publisher : Cambridge University Press
Page : 199 pages
File Size : 30,80 MB
Release : 2013-07-04
Category : Medical
ISBN : 1107034477
Stem cell science has the potential to impact human reproductive medicine significantly - cutting edge technologies allow the production and regeneration of viable gametes from human stem cells offering potential to preciously infertile patients. Written by leading experts in the field Stem Cells in Reproductive Medicine brings together chapters on the genetics and epigenetics of both the male and female gametes as well as advice on the production and regeneration of gene cells in men and women, trophoblasts and endometrium from human embryonic and adult stem cells. Although focussing mainly on the practical elements of the use of stem cells in reproductive medicine, the book also contains a section on new developments in stem cell research. The book is essential reading for reproductive medicine clinicians, gynecologists and embryologists who want to keep abreast of practical developments in this rapidly developing field.
Author : Maritza Jaramillo
Publisher : Frontiers Media SA
Page : 228 pages
File Size : 15,74 MB
Release : 2020-06-15
Category :
ISBN : 2889637891
Author : Ron Milo
Publisher : Garland Science
Page : 399 pages
File Size : 10,1 MB
Release : 2015-12-07
Category : Science
ISBN : 1317230698
A Top 25 CHOICE 2016 Title, and recipient of the CHOICE Outstanding Academic Title (OAT) Award. How much energy is released in ATP hydrolysis? How many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid
Author : Lucy W. Barrett
Publisher : Springer Science & Business Media
Page : 63 pages
File Size : 36,16 MB
Release : 2013-06-26
Category : Science
ISBN : 3034806795
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression. The major regions involved in regulation of a particular gene are the 5’ and 3’ untranslated regions and introns. In addition, pervasive transcription of complex genomes produces a variety of non-coding transcripts that interact with these regions and contribute to regulation. This book discusses recent insights into the regulatory roles of the untranslated gene regions and non-coding RNAs in the control of complex gene expression, as well as the implications of this in terms of organism complexity and evolution.