Translational Research in Traumatic Brain Injury


Book Description

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme




Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans


Book Description

The Veterans Benefits Administration (VBA) provides disability compensation to veterans with a service-connected injury, and to receive disability compensation from the Department of Veterans Affairs (VA), a veteran must submit a claim or have a claim submitted on his or her behalf. Evaluation of the Disability Determination Process for Traumatic Brain Injury in Veterans reviews the process by which the VA assesses impairments resulting from traumatic brain injury for purposes of awarding disability compensation. This report also provides recommendations for legislative or administrative action for improving the adjudication of veterans' claims seeking entitlement to compensation for all impairments arising from a traumatic brain injury.




Traumatic Brain Injury


Book Description

This thoroughly revised and updated work covers numerous advances in traumatic brain injury diagnosis, evaluation, treatment, and pathophysiology. Since publication of the first edition in 2012, there has been greatly increased public awareness of the clinical consequences of even the mildest of head injuries, and the result has been a concerted effort of countries around the world to increase research funding. This second edition continues to focus on mild traumatic brain injury--or concussion--and contains updates to all the original chapters as well as adding new chapters addressing clinical sequelae, including pediatric concussion, visual changes, chronic traumatic encephalopathy, and blast-associated TBI. Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation, Second Edition, is a comprehensive resource designed for neurologists, primary care clinicians, sports physicians, and other medical providers, including psychologists and neuropsychologists, as well as athletic trainers who may evaluate and care for individuals who have sustained a TBI. The book features summaries of the most pertinent areas of diagnosis and therapy, which can be readily accessed by the busy clinician/professional. In addition, the book's treatment algorithms provide a highly practical reference to cutting edge therapies, and an updated appendix of ICD codes is included. An outstanding contribution to the literature, Traumatic Brain Injury: A Clinician's Guide to Diagnosis, Management, and Rehabilitation, Second Edition, again offers an invaluable resource for all providers who treat patients with TBI.




Traumatic Brain Injury, Part II


Book Description

The Handbook of Clinical Neurology volumes on Traumatic Brain Injury (TBI) provide the reader with an updated review of emerging approaches to TBI research, clinical management and patient rehabilitation. Chapters in Part II offer coverage of clinical sequelae and long-term outcome, brain plasticity and long-term risks, and clinical trials. Contemporary investigations on blast injury and chronic traumatic encephalopathy are presented, making this state-of-the-art volume a must have for clinicians and researchers concerned with the clinical management, or investigation, of TBI.




Brain Neurotrauma


Book Description

With the contribution from more than one hundred CNS neurotrauma experts, this book provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma including biomarker studies, experimental models, diagnostic methods, and neurotherapeutic intervention strategies in brain injury research. It discusses neurotrauma mechanisms, biomarker discovery, and neurocognitive and neurobehavioral deficits. Also included are medical interventions and recent neurotherapeutics used in the area of brain injury that have been translated to the area of rehabilitation research. In addition, a section is devoted to models of milder CNS injury, including sports injuries.




Textbook of Traumatic Brain Injury, Third Edition


Book Description

Despite the increased public awareness of traumatic brain injury (TBI), the complexities of the neuropsychiatric, neuropsychological, neurological, and other physical consequences of TBI of all severities across the lifespan remain incompletely understood by patients, their families, healthcare providers, and the media. Keeping pace with advances in the diagnosis, treatment, and science of TBI, the Textbook of Traumatic Brain Injury, Third Edition, comprehensively fills this gap in knowledge. Nearly all 50 chapters feature new authors, all of them experts in their field. Chapters new to this edition include biomechanical forces, biomarkers, neurodegenerative dementias, suicide, endocrine disorders, chronic disease management, and social cognition. An entirely new section is devoted to the evaluation and treatment of mild TBI, including injuries in athletes, military service members and veterans, and children and adolescents. These chapters join newly updated sections on the assessment and treatment of the cognitive, emotional, behavioral, and other physical sequelae of TBI. The Textbook of Traumatic Brain Injury is a must-read for all of those working in any of the multitude of disciplines that contribute to the care and rehabilitation of persons with brain injury. This new volume is also a potentially useful reference for policymakers in both the public and private sectors.




Management of Adults with Traumatic Brain Injury


Book Description

Management of Adults with Traumatic Brain Injury is an up-to-the-minute, comprehensive, and useful text designed to support busy physicians, nurses, and mental health professionals working with persons with traumatic brain injury (TBI) and their families. Understanding and improving outcomes after TBI requires consideration of the effects of biomechanical forces on the brain and the interactions between the injury, the person experiencing it, and the psychosocial context in which TBI and its consequences occur. A multidisciplinary approach to the management of persons with TBI therefore is essential. Accordingly, this book presents and synthesizes the work of internationally recognized brain injury clinicians, scientists, and educators who were selected by a team of editors with backgrounds in psychiatry, neurology, psychology, and physiatry. This broad range of perspectives enhances understanding and provides nuanced yet practical information on the neuropsychiatric management of persons with TBI. Evidence-informed, concise, and clinically rich, Management of Adults with Traumatic Brain Injury will be of enormous value to health care providers grappling with the neurological and mental health consequences of this widespread public health problem.




Manual of Traumatic Brain Injury


Book Description

The Manual provides an excellent road map to the many topics relevant in the diagnosis, treatment, and long-term management of individuals with TBI. As such, the book can serve either as a fine introduction for the uninitiated or as a valued reference for seasoned clinicians. I highly recommend [it]... Journal of Head Trauma Rehabilitation This is a stellar quality book that will be beneficial for every member of the multidisciplinary team that is required to treat patients with TBI. It offers a concise but broad and informative view of the disorder, and can serve as an easy-to-read and access primary text. 4 Stars! Doody’s Reviews Now completely revised and updated, Manual of Traumatic Brain Injury:Assessment and Management, Second Edition is a comprehensive evidence-based guide to brain injury diagnosis, treatment, and recovery, delivered in a succinct format designed for targeted access to essential content. This concise text, featuring internationally known contributors drawn from leading TBI programs, is organized into five sections. Part 1 discusses fundamental concepts needed to provide a context for clinical decision-making. Part 2 covers mild TBI, from natural history to sports-related concussion, post-concussion syndrome, and more. Part 3 focuses on moderate to severe TBI and contains chapters on pre-hospital, emergency and ICU care, rehabilitation, community reintegration, management of associated impairments, and post-injury outcomes. Part 4 covers the complications and long-term sequelae that may arise in patients with TBI, including spasticity, movement disorders, posttraumatic seizures, hydrocephalus, behavioral and sleep disturbances, and chronic traumatic encephalopathy (CTE). Part 5 focuses on special considerations and resources, including issues specific to selected populations or injury environments (military, pediatric, workers compensation and older patients), as well as return to work and medico-legal issues in TBI. Comprehensively updated to reflect the current state of the art in this rapidly evolving field, this book is a must-have for neurologists, physiatrists, primary care physicians, mental health professionals, social workers, and other healthcare providers who treat TBI patients. New to the Second Edition: "Key Points" section in each chapter crystallizes important clinical pearls New chapters cover anoxia complicating TBI, screening for emotional distress in TBI patients, management of chronic behavioral disturbances, and assistive technology Every chapter has been updated to reflect current evidence-based practice




New Therapeutics for Traumatic Brain Injury


Book Description

New Therapeutics for Traumatic Brain Injury: Prevention of Secondary Brain Damage and Enhancement of Repair and Regeneration explores traumatic brain injury (TBI), a major cause of death and disability throughout the world. The delayed nature of the secondary injury phase suggests that there is a therapeutic window for pharmacological interventions or other approaches to prevent progressive tissue damage and improve functional outcomes. It is now apparent that therapeutic interventions should entail both protective and repair/regeneration strategies depending on the phase of brain injury. This book describes emerging experimental strategies for the treatment of TBI, including new anti-inflammatory or anti-apoptotic therapeutics that limit brain damage, and novel or repurposed drugs that enhance repair or regeneration of the brain after injury. Comprehensive overview of basic approaches and translational development of new therapies for TBI Edited by a prominent TBI researcher that includes contributions by leading global researchers in the field Presents a great resource for researchers and practitioners to learn more about the many evolving preclinical studies and clinical trials currently underway, and the challenges of bringing translational studies in TBI to the clinic




Rehabilitation After Traumatic Brain Injury


Book Description

Covering the full spectrum of rehabilitation after traumatic brain injury, this practical reference by Drs. Blessen C. Eapen and David X. Cifu presents best practices and considerations for numerous patient populations and their unique needs. In an easy-to-read, concise format, it covers the key information you need to guide your treatment plans and help patients relearn critical life skills and regain their independence. - Covers neuroimaging, neurosurgical and critical care management, management of associated complications after TBI, pharmacotherapy, pain management, sports concussion, assistive technologies, and preparing patients for community reintegration. - Discusses special populations, including pediatric, geriatric, and military and veteran patients. - Consolidates today's available information and guidance in this challenging and diverse area into one convenient resource.