Turning Blood Red


Book Description

disorders, and heart disease. It also provides new insights which may lead to new therapies." --Book Jacket.




Turning Blood Red: The Fight For Life In Cooley's Anemia


Book Description

This book is the story of an inherited blood disease — Cooley's anemia or beta thalassemia. Cooley's anemia is a severe and potentially fatal anemia that affects millions of people worldwide. Written by a world-recognized expert on the disease who has contributed greatly to the scientific understanding of the pathophysiology of this human hemoglobin disorder, the book describes the emotional and medical impact of the disease on patients and their families. It also summarizes the research on the disease at the level of the genes, DNA, RNA, and proteins. In addition, it also includes chapters on current therapy and future approaches to the disease, such as gene therapy, stem cell transplantation, and antenatal diagnosis.A multidisciplinary book covering the fields of hematology, pediatrics, medicine, genetics, and molecular biology, the book details how Cooley's anemia serves as a model for understanding other human genetic and acquired diseases such as cancer, neurological disorders, and heart disease. It also provides new insights which may lead to new therapies.




Iron Boy


Book Description

If you ask people about their earliest memories, most will recall holidays and family parties. But for Arthur, many of his earliest memories include going with his parents to regular hospital visits and staying overnight for blood transfusions. These treatments have been a frequent part of his life since birth because he has beta-thalassemia major: a rare genetic disorder that reduces his body's ability to produce enough healthy red blood cells. When reaching adolescence, most teenagers want more freedom, independence and control in their lives. For Arthur, it was the opposite, as he discovered that his lifespan would only last up to adulthood. After becoming an adult, Arthur was waiting for his death. It was at the eleventh hour, at the age of twenty-one, when Arthur was introduced to a miracle treatment, but only after the damage of iron overload from all the blood transfusion was done to his body. Grateful to be given a chance to survive for a few more years, Arthur decided to do something with his life; to get married, buy a house and also to have children, knowing he had no prospect of any future for himself.




The Thalassemias


Book Description




Clinical Case Studies for the Family Nurse Practitioner


Book Description

Clinical Case Studies for the Family Nurse Practitioner is a key resource for advanced practice nurses and graduate students seeking to test their skills in assessing, diagnosing, and managing cases in family and primary care. Composed of more than 70 cases ranging from common to unique, the book compiles years of experience from experts in the field. It is organized chronologically, presenting cases from neonatal to geriatric care in a standard approach built on the SOAP format. This includes differential diagnosis and a series of critical thinking questions ideal for self-assessment or classroom use.




Diagnosis of Blood and Bone Marrow Disorders


Book Description

This book focuses on hematopoietic and lymphoid neoplasms that initially present as peripheral blood abnormalities, with either cytopenias or elevated peripheral blood counts, as well as non-neoplastic conditions that may raise concern for a hematologic malignancy. The scope of the book includes myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), mixed myelodysplastic/myeloproliferative neoplasms (MDS/MPN), as well as lymphomas and lymphoid leukemias that typically present initially with peripheral blood abnormalities. Within each category, a comprehensive list of differential diagnoses is discussed. For each disease entity, the reader is updated with new molecular genetic data, biomarkers, and recent applications of immunophenotyping, and how to incorporate the new information in disease diagnosis and classifications is illustrated, including the use of diagnostic algorithms where appropriate. The book employs the revised WHO Classification of Hematopoietic Neoplasms for all disease entities. Diagnosis of Blood and Bone Marrow Disorders will serve as a very useful resource for pathologists, pathologists in training, hematologists and medical technologists who are involved in the clinical work-up of patients with bone marrow and blood neoplasms. It will provide a practical and concise yet comprehensive review.




American Medical Association Complete Medical Encyclopedia


Book Description

This is a brand new, state-of-the art consumer medical encyclopedia from America's most trusted authority, aimed at the 30+ reader who still trusts a distinguished reference book more than the Internet, and who cares profoundly about his or her own health and that of the whole family. The AMA literally started from scratch to produce this book, so it is in no way to be considered a revision of any previously published title. Special features include: a mil-color Atlas of the Body; sections on 21st century medicine including genetics, brain imaging, robotic surgery, and other cutting edge topics; 40 symptom charts; and a heavily illustrated First Aid section with stcp-by-step suggestions for handling common injuries at home. It has extensive coverage of Alternative Medicine: 80 separate entries and several sidebars that cover the latest in alternative therapies, all edited and reviewed by physicians involved in alternative medicine. The fact that AMA is addressing alternative medicine when the competition largely avoids the topic proves that they know what today's health care consumer wants. AMA Complete Medical Encyclopedia devotes considerable space to mental health issues, with 229 entries on a wide range of Psychiatry topics. It has 129 entries on nutrition, and also covers exercise, sports medicine, and cosmetic surgery. It covers death and dying; home care; geriatric concerns; and specific life stages. Every entry, sidebar, illustration and feature was reviewed by one or more medical doctors, and specialists from dozens of fields reviewed me text and art for accuracy. The book has 6,000 entries covering about 2,000 illnesses and definitions for about 500 different tests and surgical procedures, plus a complete pharmacology section. It has more than 1,750 illustrations, all of which were created for this book, including 32 pages of color.




Patient Blood Management


Book Description

Patient Blood Management (PBM) is an innovative clinical concept that aims to reduce the need for allogenic blood transfusions, cut health-care costs, and avert or correct the risk factors related to blood transfusion, thus minimizing the rate of side effects and complications. This comprehensive hands-on volume offers a three-point approach for the implementation of PBM to improve patient outcome, focusing on how to prevent or treat anemia, reduce blood loss, and increase anemia tolerance. The book also goes beyond preoperative PBM, with detailed accounts of coagulation disorder management and the administration of coagulation products and platelet concentrates. Special Features: Presents a clear three-pillar strategy for the application of PBM: diagnosis and treatment of anemia, reduction of peri-interventional blood loss, and optimization of the tolerance to anemia in the everyday clinical setting Covers issues such as PBM during surgery, requirements for modern transfusion medicine, ordering blood products, the role of pre-anesthesia clinics, benchmarking processes, and potential implications of PBM in the public health sector Overview of research in PBM including landmark studies and current clinical trials Boxes in each chapter highlighting key information, core statements, and summaries A multidisciplinary and international team of contributors experienced in PBM Patient Blood Management is a guide for clinicians and residents whose patients are at risk for anemia, coagulation disorders, or severe blood loss. Anesthesiologists, surgeons, and specialists involved in the use of blood and blood products can use the book for quick reference or to learn more about a leading-edge concept for optimizing patient safety and improving outcome.




Iron Chelation Therapy


Book Description

Within the last few years, iron research has yielded exciting new insights into the understanding of normal iron homeostasis. Such development, and the evolution of improved strategies of Iron Chelating Therapy require better understanding of the pathophysiology of iron toxicity and the mechanism of action of iron chelating drugs. The timeliness of the present volume is underlined by several significant developments in recent years. New insights have been gained into the molecular basis of aberrant iron handling in hereditary disorders and the pathophysiology of iron overload. This volume highlights the impact of long term Iron Celating Therapy using deferoxamine or the new, but controversial oral iron chelator deferiprone based on experience gained by multicenter trails, with special emphasis on survival, morbidity and drug toxicity; it reviews the development of the new and improved orally effective chelators suitable for clinical use in the near future and examines novel strategies of iron chelating treatment for the control of cell proliferation in malignant disease or malaria.




Basics of Blood Management


Book Description

To reduce transfusion-related morbidity and mortality, it is recommended that an integrated approach to blood management is employed using all available tools to reduce a patient's exposure to donor blood. Meeting the need for a book covering the concepts of blood management as a trend towards multidisciplinary blood management, this new edition is an important resource, providing healthcare professionals with a tool to develop background knowledge in blood management, its organization, methods and tools. Practicing clinicians will be fully prepared to successfully start and run blood management programs.