Automated Insulin Delivery


Book Description

Automated insulin delivery goes by many names: hybrid or full closed loop; artificial pancreas system (APS); "looping" and more. They are not all the same, though. You have choices, ranging from the type of pump body and CGM you want to use, to the algorithm and controller, to the interoperability and remote monitoring options, and more. Like switching from multiple daily injections to an insulin pump, switching from manual diabetes to automated insulin delivery has a learning curve. It's certainly one you can tackle. After all, you're already tackling type 1 diabetes! You already have the base knowledge and experience you need to succeed with a closed loop system, if it's right for you. But you might be wondering how to get ahead of your learning curve before you start or even choose an APS, or you've started and want to dig even deeper into optimizing how an automated insulin delivery system fits into your lifestyle. This book was written for you! It leverages the collective knowledge of the early adopters of do-it-yourself and commercial systems from the past five years and packages it into easy, understandable guides and lessons learned.In this book, you'll find new analogies to help you understand - and explain - this new method of diabetes management, and tips on how to communicate with your healthcare provider(s) about it. You'll see stories and examples from real families and individuals living with type 1 diabetes and how they benefit from artificial pancreas systems, and why they chose and continue to choose to use them. You'll be empowered to understand the basic components of artificial pancreas systems, how they work, and what questions to ask as you peruse your choices now and in the future. This book also includes a foreword by Aaron Kowalski, President and CEO of JDRF, and co-founder of the JDRF Artificial Pancreas Project. "I will immediately recommend this book not just to people looking to use a DIY closed loop system, but also to anybody looking to improve their grasp on the management of type 1 diabetes, whether patient, caregiver, or healthcare provider." - Aaron Neinstein, MD (Endocrinologist, UCSF)




Understanding Insulin and Insulin Resistance


Book Description

Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance. The design is systematic and meticulous, portraying topics in a flow from simple to complex. This resource is intended for a broad audience spanning across biochemistry, medicine, dentistry, academia, physicians, and research scholars. It extends the approach to biochemistry, physiology, metabolism of insulin along with the coverage of pathophysiology of insulin resistance, its effects on the body tissues, and its analysis on insulin resistance syndrome.




Glucose Monitoring Devices


Book Description

Glucose Monitoring Devices: Measuring Blood Glucose to Manage and Control Diabetes presents the state-of-the-art regarding glucose monitoring devices and the clinical use of monitoring data for the improvement of diabetes management and control. Chapters cover the two most common approaches to glucose monitoring–self-monitoring blood glucose and continuous glucose monitoring–discussing their components, accuracy, the impact of use on quality of glycemic control as documented by landmark clinical trials, and mathematical approaches. Other sections cover how data obtained from these monitoring devices is deployed within diabetes management systems and new approaches to glucose monitoring. This book provides a comprehensive treatment on glucose monitoring devices not otherwise found in a single manuscript. Its comprehensive variety of topics makes it an excellent reference book for doctoral and postdoctoral students working in the field of diabetes technology, both in academia and industry. - Presents a comprehensive approach that spans self-monitoring blood glucose devices, the use of continuous monitoring in the artificial pancreas, and intraperitoneal glucose sensing - Provides a high-level descriptions of devices, as well as detailed mathematical descriptions of methods and techniques - Written by experts in the field with vast experience in the field of diabetes and diabetes technology




Psychosocial Care for People with Diabetes


Book Description

Psychosocial Care for People with Diabetes describes the major psychosocial issues which impact living with and self-management of diabetes and its related diseases, and provides treatment recommendations based on proven interventions and expert opinion. The book is comprehensive and provides the practitioner with guidelines to access and prescribe treatment for psychosocial problems commonly associated with living with diabetes.




The Artificial Pancreas


Book Description

The Artificial Pancreas: Current Situation and Future Directions presents research on the top issues relating to the artificial pancreas (AP) and its application to diabetes. AP is a newer form of treatment to accurately and efficiently inject insulin, thereby significantly improving the patient's quality of life. By connecting a continuous glucose monitor (CGM) to a continuous subcutaneous insulin infusion using a control algorithm, AP delivers and regulates the most accurate amount of insulin to maintain normal glycemic values. Featured chapters in this book are written by world leaders in AP research, thus providing readers with the latest studies and results. - Focuses on Type 1 Diabetes Mellitus (T1DM) that is primarily found in children and typically treated by means of a syringe or insulin pump - Features research and results from top academic experimental groups, and from universities such as Harvard (USA), the University of Virginia (USA), the University of Padova (Italy), the University of Montpellier (France), and the Buenos Aires Institute of Technology (Argentina) - Discusses clinical trials of AP from around the world, including the United States, the EU, Latin America, and Israel




Controlled Drug Delivery Systems


Book Description

This book will describe current research on drug delivery systems that encompass four broad categories, namely: routes of delivery, delivery vehicles, payload, and targeting strategies. Where appropriate delivery vehicles and relevant release of specific agents in any of these categories in clinical application will be discussed. All chapters will highlight the translational aspects of the various technologies discussed and will provide insights into the advantages of such delivery systems over current ones in clinical or research use. Each technology reviewed in this book will have significant potential to improve patients' lives by enhancing the therapeutic efficacy of drugs. This book: Discusses the various factors that mitigate effective oral insulin delivery and the current status of research efforts to overcome these barriers along with recent clinical projections Examines the advantages and disadvantages of each drug delivery system Examines the standard method of accomplishing controlled drug release through the incorporation of the drugs within polymeric biomaterials such as capsules and microcapsules as well as other vehicles such as liposomes Discusses various controlled drug delivery systems, including sustained release delivery systems and pulse or delayed release, e.g. to target different regions of the gastrointestinal tract. In view of these wide-ranging technological areas, and the up-to-date discussions of opportunities and challenges associated with these applications, the book should provide readers from technology, materials science, pharmacology and clinical disciplines with very valuable information.




Insulin Pump Therapy and Continuous Glucose Monitoring


Book Description

This title combines a detailed discussion of the evidence-base for all aspects of CSII in adults and children with a practical guide to treating people with diabetes using insulin pump therapy.










Pumping Insulin: Everything for Success on an Insulin Pump and Cgm


Book Description

Table of Contents: 1) Benefits of an Insulin Pump, 2) All About CGMs, 3) Select a Pump and Infusion Set, 4) Carb Counting, 5) Reach Your Glucose Goals, 6) Start on a Pump, 7) Essentials of the Bolus Calculator, 8) Tools for Better BC Settings, 9) Your TDD, 10) Choose, Check and Change Your Basal Rates, 11) Check and Change Your Carb Factor, 12) Choose, Check and Change Your Correction Factor, 13) Unwanted Glucose Patterns, 14) Real-Time CGM, 15) Stop Highs from the Infusion Set, 16) Hypoglycemia, 17) Ketoacidosis, 18) Erratic Readings, 19) Exercise and Diabetes, 20) Children and Teens, 21) Pumps in Type 1.5 and Type 2 Diabetes