Priorities for the National Vaccine Plan


Book Description

Vaccination is a fundamental component of preventive medicine and public health. The use of vaccines to prevent infectious diseases has resulted in dramatic decreases in disease, disability, and death in the United States and around the world. The current political, economic, and social environment presents both opportunities for and challenges to strengthening the U.S. system for developing, manufacturing, regulating, distributing, funding, and administering safe and effective vaccines for all people. Priorities for the National Vaccine Plan examines the extraordinarily complex vaccine enterprise, from research and development of new vaccines to financing and reimbursement of immunization services. Priorities for the National Vaccine Plan examines the extraordinarily complex vaccine enterprise, from research and development of new vaccines to financing and reimbursement of immunization services. The book makes recommendations about priority actions in the update to the National Vaccine Plan that are intended to achieve the objectives of disease prevention and enhancement of vaccine safety. It is centered on the plan's five goals in the areas of vaccine development, safety, communication, supply and use, and global health.




Wildlife in a Changing World


Book Description

"Wildlife in a Changing World" presents an analysis of the 2008 IUCN Red List of Threatened Species. Beginning with an explanation of the IUCN Red List as a key conservation tool, it goes on to discuss the state of the world s species and provides the latest information on the patterns of species facing extinction in some of the most important ecosystems in the world, highlighting the reasons behind their declining status. Areas of focus in the report include: freshwater biodiversity, the status of the world s marine species, species susceptibility to climate change impacts, the Mediterranean biodiversity hot spot, and broadening the coverage of biodiversity assessments."







Market Definition in EU Competition Law


Book Description

The maintenance of a fair, competitive market among member states is critical to the functioning of the EU economy. In this book, the first comprehensive, unifying view of market definition, Miguel Ferro adeptly explores the different economic-legal issues that arise in EU competition law.







Snakes


Book Description

Destruction of habitat due to urban sprawl, pollution, and deforestation has caused population declines or even extinction of many of the world's approximately 2,600 snake species. Furthermore, misconceptions about snakes have made them among the most persecuted of all animals, despite the fact that less than a quarter of all species are venomous and most species are beneficial because they control rodent pests. It has become increasingly urgent, therefore, to develop viable conservation strategies for snakes and to investigate their importance as monitors of ecosystem health and indicators of habitat sustainability. In the first book on snakes written with a focus on conservation, editors Stephen J. Mullin and Richard A. Seigel bring together leading herpetologists to review and synthesize the ecology, conservation, and management of snakes worldwide. These experts report on advances in current research and summarize the primary literature, presenting the most important concepts and techniques in snake ecology and conservation. The common thread of conservation unites the twelve chapters, each of which addresses a major subdiscipline within snake ecology. Applied topics such as methods and modeling and strategies such as captive rearing and translocation are also covered. Each chapter provides an essential framework and indicates specific directions for future research, making this a critical reference for anyone interested in vertebrate conservation generally or for anyone implementing conservation and management policies concerning snake populations. Contributors: Omar Attum, Indiana University Southeast; Steven J. Beaupre, University of Arkansas; Xavier Bonnet, Centre National de la Recherche Scientifique; Frank T. Burbrink, College of Staten Island-The City University of New York; Gordon M. Burghardt, University of Tennessee; Todd A. Castoe, University of Colorado; David Chiszar, University of Colorado; Michael E. Dorcas, Davidson College; Lara E. Douglas, University of Arkansas; Christopher L. Jenkins, Project Orianne, Ltd.; Glenn Johnson, State University of New York at Potsdam; Michael Hutchins, The Wildlife Society; Richard B. King, Northern Illinois University; Bruce A. Kingsbury, Indiana University-Purdue University Fort Wayne; Thomas Madsen, University of Wollongong; Stephen J. Mullin, Eastern Illinois University; James B. Murphy, National Zoological Park; Charles R. Peterson, Idaho State University; Kent A. Prior, Parks Canada; Richard A. Seigel, Towson University; Richard Shine, University of Sydney; Kevin T. Shoemaker, College of Environmental Science and Forestry, State University of New York; Patrick J. Weatherhead, University of Illinois; John D. Willson, University of Georgia




Early Drug Development, 2 Volume Set


Book Description

This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies. Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues. After introducing the overall early development workflow, the critical steps of early drug development are described in a sequential and enabling order: the availability of the drug substance and that of the drug product, the prediction of pharmacokinetics and -dynamics, as well as that of drug safety. The final section focuses on intellectual property aspects during early clinical development. The emphasis throughout is on recent case studies to exemplify salient points, resulting in an abundance of practice-oriented information that is usually not available from other sources. Aimed at medicinal chemists in industry as well as academia, this invaluable reference enables readers to understand and navigate the challenges in developing clinical candidate molecules that can be successfully used in phase one clinical trials.







Temperate and Boreal Rainforests of the World


Book Description

Temperate rainforests are biogeographically unique. Compared to their tropical counterparts, temperate rainforests are rarer and are found disproportionately along coastlines. Because most temperate rainforests are marked by the intersection of marine, terrestrial, and freshwater systems, these rich ecotones are among the most productive regions on Earth. Globally, temperate rainforests store vast amounts of carbon, provide habitat for scores of rare and endemic species with ancient affinities, and sustain complex food-web dynamics. In spite of their global significance, however, protection levels for these ecosystems are far too low to sustain temperate rainforests under a rapidly changing global climate and ever expanding human footprint. Therefore, a global synthesis is needed to provide the latest ecological science and call attention to the conservation needs of temperate and boreal rainforests. A concerted effort to internationalize the plight of the world’s temperate and boreal rainforests is underway around the globe; this book offers an essential (and heretofore missing) tool for that effort. DellaSala and his contributors tell a compelling story of the importance of temperate and boreal rainforests that includes some surprises (e.g., South Africa, Iran, Turkey, Japan, Russia). This volume provides a comprehensive reference from which to build a collective vision of their future.