Unraveling Chromatin


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Index Medicus


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Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.




Allergy and Allergic Diseases


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Reserve your copy now This two volume book is an outstanding reference source on allaspects of allergy and allergic diseases. Covering virtually everyallergic condition, from the immunological and molecular basis ofthe allergic response to future trends in allergic diseaseprevention, this new international editorial team (A.B.Kay, JeanBousquet, Pat Holt and Allen Kaplan) have completely revised andupdated the text, from both a scientific and clinical perspective.References will continue to be added to the text until it goes topress making this the most up-to-date book available in thefield. This second edition consists of more than 1,800 pages containedwithin 98 chapters. The price includes a fully searchable companion CD ROM with thecomplete text and over 300 images from the book in full colour.




Epigenetic Memory and Control in Plants


Book Description

Epigenetics commonly acts at the chromatin level modulating its structure and consequently its function in gene expression and as such plays a critical role in plant response to internal and external cues. This book highlights recent advances in our understanding of epigenetic mechanisms as a major determinant through which internal and external signals, such as those occurring during hybridization, flowering time, reproduction and response to stress, communicate with plant cells to bring about activation of multiple nuclear processes and consequently plant growth and development. The outcome of these processes may persist for generations long after the initial cues have expired and may contribute to plant evolution.




Cellular Mechanics and Biophysics


Book Description

This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.







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Fundamentals of Chromatin


Book Description

​​​​​​​​​​​​​While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin. ​Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication. The audience for this book is mainly newly established scientists ​and graduate students. Rather than going into the more specific areas of recent research on chromatin the chapters in this book give a strong, updated groundwork about the topic. Some the fundamentals that this book will cover include the structure of chromatin and biochemistry and the enzyme complexes that manage it.




DNA Damage, DNA Repair and Disease


Book Description

The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.