Use and Abuse of Amphetamine and Its Substitutes
Author : James V. Spotts
Publisher :
Page : 582 pages
File Size : 18,73 MB
Release : 1980
Category : Amphetamine abuse
ISBN :
Author : James V. Spotts
Publisher :
Page : 582 pages
File Size : 18,73 MB
Release : 1980
Category : Amphetamine abuse
ISBN :
Author : Mary V. Solanto
Publisher : Oxford University Press, USA
Page : 434 pages
File Size : 50,12 MB
Release : 2001
Category : Medical
ISBN : 9780195133714
Stimulant drugs are widely used in the treatment of ADHD in children and adults. Hundreds of studies over the past 60 years have demonstrated their effectiveness in improving attention span, increasing impulse control, and reducing hyperactivity and restlessness. Despite widespread interest in these compounds, however, their mechanisms of action in the central nervous system have remained poorly understood. Recent advances in the basic and clinical neurosciences now afford the possibility of elucidating these mechanisms. The current volume is the first to bring this expanding knowledge to bear on the central question of why and how stimulants exert their therapeutic effects. The result is a careful, comprehensive, and insightful integration of material by well-known scientists that significantly advances our understanding of stimulant effects and charts a course for future research. Part I presents a comprehensive description of the clinical features of ADHD and the clinical response to stimulants. Part II details the cortical and subcortical neuroanatomy and functional neurophysiology of dopamine and norepinephrine systems with respect to the regulation of attention, arousal, activity, and impulse control and the effects of stimulants on these systems. Part III is devoted to clinical research, including recent studies of neuroimaging, genetics, pharmacodynamic and pharmacokinetic properties of stimulants, effects on cognitive functions, neurophysiological effects in humans with and without ADHD and in non-human primates, and comparison of stimulants and non-stimulants in the treatment of ADHD. Part IV is a masterful synthesis that presents alternative models of stimulant drug action and generates key hypotheses for continued research. The volume will be of keen interest to researchers and clinicians in psychiatry, psychology, and neurology, neuroscientists studying stimulants, and those pursuing development of new drugs to treat ADHD.
Author : Robert Vink
Publisher : University of Adelaide Press
Page : 354 pages
File Size : 14,65 MB
Release : 2011
Category : Medical
ISBN : 0987073052
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author : James V. Spotts
Publisher :
Page : 588 pages
File Size : 30,94 MB
Release : 1980
Category : Amphetamine abuse
ISBN :
Author : Norman Ohler
Publisher : HarperCollins
Page : 307 pages
File Size : 17,4 MB
Release : 2017-03-07
Category : History
ISBN : 1328664090
A New York Times bestseller, Norman Ohler's Blitzed is a "fascinating, engrossing, often dark history of drug use in the Third Reich” (Washington Post). The Nazi regime preached an ideology of physical, mental, and moral purity. Yet as Norman Ohler reveals in this gripping history, the Third Reich was saturated with drugs: cocaine, opiates, and, most of all, methamphetamines, which were consumed by everyone from factory workers to housewives to German soldiers. In fact, troops were encouraged, and in some cases ordered, to take rations of a form of crystal meth—the elevated energy and feelings of invincibility associated with the high even help to account for the breakneck invasion that sealed the fall of France in 1940, as well as other German military victories. Hitler himself became increasingly dependent on injections of a cocktail of drugs—ultimately including Eukodal, a cousin of heroin—administered by his personal doctor. Thoroughly researched and rivetingly readable, Blitzed throws light on a history that, until now, has remained in the shadows. “Delightfully nuts.”—The New Yorker
Author :
Publisher : Academic Press
Page : 759 pages
File Size : 34,56 MB
Release : 2013-05-17
Category : Psychology
ISBN : 0123983606
Biological Research on Addiction examines the neurobiological mechanisms of drug use and drug addiction, describing how the brain responds to addictive substances as well as how it is affected by drugs of abuse. The book's four main sections examine behavioral and molecular biology; neuroscience; genetics; and neuroimaging and neuropharmacology as they relate to the addictive process. This volume is especially effective in presenting current knowledge on the key neurobiological and genetic elements in an individual's susceptibility to drug dependence, as well as the processes by which some individuals proceed from casual drug use to drug dependence. Biological Research on Addiction is one of three volumes comprising the 2,500-page series, Comprehensive Addictive Behaviors and Disorders. This series provides the most complete collection of current knowledge on addictive behaviors and disorders to date. In short, it is the definitive reference work on addictions. - Each article provides glossary, full references, suggested readings, and a list of web resources - Edited and authored by the leaders in the field around the globe – the broadest, most expert coverage available - Discusses the genetic basis of addiction - Covers basic science research from a variety of animal studies
Author :
Publisher :
Page : 76 pages
File Size : 38,89 MB
Release : 2007
Category : Brain
ISBN :
Author : Casey Schwartz
Publisher : Vintage
Page : 257 pages
File Size : 39,35 MB
Release : 2020-04-07
Category : Biography & Autobiography
ISBN : 1524747114
"A rich inquiry into what it means to pay (and maintain) attention in a world increasingly permeated with distraction and interference.” —Publisher’s Weekly Combining expert storytelling with genuine self-scrutiny, Casey Schwartz details the decade she spend taking Adderall to help her pay attention (or so she thought) and then considers the role of attention in defining our lives as it has been understood by thinkers such as William James, David Foster Wallace, and Simone Weil. From our craving for distraction to our craving for a cure, from Silicon Valley consultants and psychedelic researchers to the findings of trauma expert Dr. Gabor Maté, Schwartz takes us on an eye-opening tour of the modern landscape of attention. Blending memoir, biography, and original reporting, Schwarz examines her attempts to preserve her authentic life and decide what is most important in it. Attention: A Love Story will resonate with readers who want to determine their own minds, away from the siren call of their screens.
Author : Dr. Carl L. Hart
Publisher : Penguin
Page : 305 pages
File Size : 43,16 MB
Release : 2022-01-11
Category : Social Science
ISBN : 1101981660
“Hart’s argument that we need to drastically revise our current view of illegal drugs is both powerful and timely . . . when it comes to the legacy of this country’s war on drugs, we should all share his outrage.” —The New York Times Book Review From one of the world's foremost experts on the subject, a powerful argument that the greatest damage from drugs flows from their being illegal, and a hopeful reckoning with the possibility of their use as part of a responsible and happy life Dr. Carl L. Hart, Ziff Professor at Columbia University and former chair of the Department of Psychology, is one of the world's preeminent experts on the effects of so-called recreational drugs on the human mind and body. Dr. Hart is open about the fact that he uses drugs himself, in a happy balance with the rest of his full and productive life as a researcher and professor, husband, father, and friend. In Drug Use for Grown-Ups, he draws on decades of research and his own personal experience to argue definitively that the criminalization and demonization of drug use--not drugs themselves--have been a tremendous scourge on America, not least in reinforcing this country's enduring structural racism. Dr. Hart did not always have this view. He came of age in one of Miami's most troubled neighborhoods at a time when many ills were being laid at the door of crack cocaine. His initial work as a researcher was aimed at proving that drug use caused bad outcomes. But one problem kept cropping up: the evidence from his research did not support his hypothesis. From inside the massively well-funded research arm of the American war on drugs, he saw how the facts did not support the ideology. The truth was dismissed and distorted in order to keep fear and outrage stoked, the funds rolling in, and Black and brown bodies behind bars. Drug Use for Grown-Ups will be controversial, to be sure: the propaganda war, Dr. Hart argues, has been tremendously effective. Imagine if the only subject of any discussion about driving automobiles was fatal car crashes. Drug Use for Grown-Ups offers a radically different vision: when used responsibly, drugs can enrich and enhance our lives. We have a long way to go, but the vital conversation this book will generate is an extraordinarily important step.
Author : Lee M. Cohen
Publisher : Routledge
Page : 964 pages
File Size : 18,32 MB
Release : 2013-03-01
Category : Medical
ISBN : 1135704007
Given the prevalence of substance abuse in general clinical populations, it is important for healthcare providers to have knowledge and skill in the treatment of these problems. Evidence-Based Practice (EBP) involves the integration of the best evidence with clinical expertise and patient values. This text is designed as a bridge for practitioners that will provide up-to-date evidence reviews as well as information on how to best keep up with emerging trends in the field. The editors have gathered expert authors to provide a much needed summary of the current status of the evidence based practice for both the assessment and treatment of specific substance use disorders.