Toxicity Assessment


Book Description

This book collects protocols from different areas of knowledge to assist in the identification of toxic effects exerted by different xenobiotics. At the same time as classical techniques are presented, modern techniques with alternative models to the use of animals are also presented. Given the ever-increasing exposure to different compounds and their effects on population health, the assessment of multiple endpoints is of utmost importance for better risk assessment, and this collection addresses that need. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Toxicity Assessment: Methods and Protocols aims to serve researchers in this vast field of science as they seek to better understand the mechanisms of action of different xenobiotics.




Advances in Energy Systems Engineering


Book Description

This book provides a scientific framework for integrated solutions to complex energy problems. It adopts a holistic, systems-based approach to demonstrate the potential of an energy systems engineering approach to systematically quantify different options at various levels of complexity (technology, plant, energy supply chain, mega-system). Utilizing modeling, simulation and optimization-based frameworks, along with a number of real-life applications, it focuses on advanced energy systems including energy supply chains, integrated biorefineries, energy planning and scheduling approaches and urban energy systems. Featuring contributions from leading researchers in the field, this work is useful for academics, researchers, industry practitioners in energy systems engineering, and all those who are involved in model-based energy systems.




Yvain


Book Description

The twelfth-century French poet Chrétien de Troyes is a major figure in European literature. His courtly romances fathered the Arthurian tradition and influenced countless other poets in England as well as on the continent. Yet because of the difficulty of capturing his swift-moving style in translation, English-speaking audiences are largely unfamiliar with the pleasures of reading his poems. Now, for the first time, an experienced translator of medieval verse who is himself a poet provides a translation of Chrétien’s major poem, Yvain, in verse that fully and satisfyingly captures the movement, the sense, and the spirit of the Old French original. Yvain is a courtly romance with a moral tenor; it is ironic and sometimes bawdy; the poetry is crisp and vivid. In addition, the psychological and the socio-historical perceptions of the poem are of profound literary and historical importance, for it evokes the emotions and the values of a flourishing, vibrant medieval past.




AMPHIBIAN CONSERVATION


Book Description

Leading amphibian biologist Semlitsch has assembled experts to tackle the timely issue of disappearing and deformed populations of amphibians. Every environmentalist will find this book an accessible and informative examination of what many scientists have called one of the major threats to the world's biodiversity.




Democracy in the Administrative State


Book Description




Managing the President's Program


Book Description

The belief that U.S. presidents' legislative policy formation has centralized over time, shifting inexorably out of the executive departments and into the White House, is shared by many who have studied the American presidency. Andrew Rudalevige argues that such a linear trend is neither at all certain nor necessary for policy promotion. In Managing the President's Program, he presents a far more complex and interesting picture of the use of presidential staff. Drawing on transaction cost theory, Rudalevige constructs a framework of "contingent centralization" to predict when presidents will use White House and/or departmental staff resources for policy formulation. He backs his assertions through an unprecedented quantitative analysis of a new data set of policy proposals covering almost fifty years of the postwar era from Truman to Clinton. Rudalevige finds that presidents are not bound by a relentless compulsion to centralize but follow a more subtle strategy of staff allocation that makes efficient use of limited bargaining resources. New items and, for example, those spanning agency jurisdictions, are most likely to be centralized; complex items follow a mixed process. The availability of expertise outside the White House diminishes centralization. However, while centralization is a management strategy appropriate for engaging the wider executive branch, it can imperil an item's fate in Congress. Thus, as this well-written book makes plain, presidential leadership hinges on hard choices as presidents seek to simultaneously manage the executive branch and attain legislative success.




Rivals for Power


Book Description

Rivals for Power is a lively description of the power struggle between the president and Congress. In it, leading congressional and presidential scholars and knowledgeable former public officials consider the historical, political, and constitutional foundations of conflict between the two branches. The authors give practical advice about how to build cooperative policymaking between the president and Congress as they struggle over major crises in solving economic problems and addressing domestic issues and the challenges in defense and foreign policy making. The book features original academic research and practitioner knowledge from the White House and the Hill. This fourth edition includes all new essays with unique and critical viewpoints on the role of the president and Congress in the policy making process. Many of the essays focus on lessons learned about cooperation and conflict between the two branches from the Clinton and Bush presidencies. The essays include preliminary analyses of President Barack Obama's relationship with Congress. Because the authors have made major contributions as congressional and presidential scholars, and have played key roles in Congress, in the White House, in the media, and as lobbyists, each chapter presents a different perspective. The new edition of Rivals for Power is intended for students, scholars, public officials, the media, and the general public. Contributions by Gary Andres, Richard S. Conley, Roger H. Davidson, The Honorable Mickey Edwards, Louis Fisher, Patrick Griffin, The Honorable Lee H. Hamilton, Mark J. Oleszek, Walter J. Oleszek, John E. Owens, James P. Pfiffner, Mark J. Rozell, Andrew Rudalevige, Barbara Sinclair, Mitchel A. Sollenberger, James A. Thurber, Stephen J. Wayne, and Joseph White.




Charles Pettigrew, First Bishop-elect of the North Carolina Episcopal Church


Book Description

This work has been selected by scholars as being culturally important and is part of the knowledge base of civilization as we know it. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. To ensure a quality reading experience, this work has been proofread and republished using a format that seamlessly blends the original graphical elements with text in an easy-to-read typeface. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.