Entropy-Enthalpy Compensation


Book Description

Professionals recognize entropy-enthalpy compensation as an important factor in molecular recognition, lead design, water networks, and protein engineering. It can be experimentally studied by proper combinations of diverse spectroscopic approaches with isothermal titration calorimetry and is clearly related to molecular dynamics. So, how should we treat entropy-enthalpy compensation? Is it a stubborn hindrance that solely complicates the predictability of phenomena otherwise laid on the line by Mother Nature? How should we then deal with it? This book dwells on these posers. It combines two chapters written by globally recognized specialists. Chapter 1 deals with general issues and suggests a definite approach to how we may answer the posers. Chapter 2 shows how the approach outlined might be successfully applied in a rational design of enzymes. This might provide other interesting strategic perspectives in the general theoretical physical chemistry field.










Integral Geometry and Representation Theory


Book Description

Generalized Functions, Volume 5: Integral Geometry and Representation Theory is devoted to the theory of representations, focusing on the group of two-dimensional complex matrices of determinant one. This book emphasizes that the theory of representations is a good example of the use of algebraic and geometric methods in functional analysis, in which transformations are performed not on the points of a space, but on the functions defined on it. The topics discussed include Radon transform on a real affine space, integral transforms in the complex domain, and representations of the group of complex unimodular matrices in two dimensions. The properties of the Fourier transform on G, integral geometry in a space of constant curvature, harmonic analysis on spaces homogeneous with respect to the Lorentz Group, and invariance under translation and dilation are also described. This volume is suitable for mathematicians, specialists, and students learning integral geometry and representation theory.




Memoir


Book Description




Compounds of Transition Metals


Book Description