zika virus disease


Book Description

Zika Virus provides an authoritative account of one of most fascinating viruses of the 21st century, covering all the main points. It includes coverage of clinical manifestations, such as fever and fatigue, but also delves into neurological manifestations like acute demyelinating neuropathy. In addition, the book discusses new evidence that suggests that Zika fever in pregnant women can cause abnormal brain development in fetuses by mother-to-child transmission. The Zika virus infection has become one of the first where women are actively discouraged from getting pregnant. Readers will find this book to be a comprehensive resource on the topic. Covers every important aspect of the Zika virus disease, from biological, to social and economic impacts Focuses on women’s health issues that have surfaced, including birth defects in newborns Written in an easy to comprehend manner, with technical terms clearly defined in chapters that highlight genetics




Zika: The Emerging Epidemic


Book Description

A gripping narrative about the origins and spread of the Zika virus by New York Times science reporter Donald G. McNeil Jr. Until recently, Zika—once considered a mild disease—was hardly a cause for global panic. But as early as August 2015, doctors in northeast Brazil began to notice a trend: many mothers who had recently experienced symptoms of the Zika virus were giving birth to babies with microcephaly, a serious disorder characterized by unusually small heads and brain damage. By early 2016, Zika was making headlines as evidence mounted—and eventually confirmed—that microcephaly is caused by the virus, which can be contracted through mosquito bites or sexually transmitted. The first death on American soil, in February 2016, was confirmed in Puerto Rico in April. The first case of microcephaly in Puerto Rico was confirmed on May 13, 2016. The virus has been known to be transmitted by the Aedes aegypti or Yellow Fever mosquito, but now Aedes albopictus, the Asian Tiger mosquito, has been found to carry it as well, which means it might affect regions as far north as New England and the Great Lakes. Right now, at least 298 million people in the Americas live in areas “conducive to Zika transmission,” according to a recent study. Over the next year, more than 5 million babies will be born. In Zika: The Emerging Epidemic, Donald G. McNeil Jr. sets the facts straight in a fascinating exploration of Zika’s origins, how it’s spreading, the race for a cure, and what we can do to protect ourselves now.




Zika in Focus


Book Description

This book addresses the most important postnatal features of Zika virus infection, providing important information on its epidemiology, pathology, clinical aspects, imaging and laboratory diagnosis. Since the report of a Zika virus infection epidemic in Northeastern Brazil in 2015, the world has paid close attention to this emergent disease. Historically, this has been the third outbreak of Zika infection described (preceded by outbreaks in Micronesia and French Polynesia), but for the first time the association with congenital microcephaly and other neurological co-morbidities in infants from women infected with the Zika virus was observed. Since then, government bodies, public health agencies, medical societies and scholars have joined forces to understand this disease, and to promote its prevention and management. Currently, the relationship between Zika virus and microcephaly is well established, as well as the most characteristic findings of congenital Zika syndrome (e.g. microcephaly, arthrogryposis, ophthalmologic and hearing abnormalities). Also, the spectrum of the disease’s severity has broadened, with less severe cases (without microcephaly) being recently recognized. Even so, there is currently a dearth of material on Zika virus infection for healthcare professional around the world. Addressing that gap, Zika In Focus – Postnatal Aspects aims to help the medical community worldwide by presenting the most important features of Zika virus infection from a postnatal perspective. It is intended to all professionals and researchers interested in this condition, especially paediatricians, radiologists and neurologists, offering them a practical guide to recognizing congenital Zika syndrome in its many aspects and focusing on the radiological pattern of lesions that can be found from the mild to the most severe cases.




Zika


Book Description

Winner of the 2017 Jabuti Book Prize The Zika virus is devastating lives and communities. Children across the Americas are being born with severe disabilities because of it. Yet during the desolating outbreak, Brazil played host to both the Olympics and the FIFA World Cup, leading many to suspect that the true impact of the virus has been subject to a cover-up of international proportions. Beginning in the northeast, where the devastation has been most felt, professor of bioethics and award-winning documentary filmmaker Debora Diniz travels across Brazil tracing the virus’s origin and spread. Along the journey she meets a host of fearless families, doctors and scientists uncovering the virus’s impact on local communities. In doing so Diniz paints a vivid picture of the Zika epidemic, exposing the Brazilian government’s complicity in allowing the virus to spread while championing the efforts of local doctors and mothers who, working together, are raising awareness of the virus and fighting for the rights of children affected by Zika.




Feminist Global Health Security


Book Description

"Global health security, focused on a firefighting short-term response efforts fail to consider the differential impacts of outbreaks on women. For example, the policy response to the Zika outbreak centred on limiting the spread of the vector through civic participation and asking women to defer pregnancy. Both actions are inherently gendered and reveal a distinct lack of consideration of the everyday lives of women. These policies placed women in a position whereby were blamed if they had a child born with Congenital Zika Syndrome, and at the same time governments required women to undertake invisible labour for vector control. What does this tell us about the role of women in global health security? This feminist critique of the Zika outbreak, argues that global health security has thus far lacked a substantive feminist engagement, with the result that the very policies created to manage an outbreak of disease disproportionately fail to protect women. Women are both differentially infected and affected by epidemics. Yet, the dominant policy narrative of global health security has created pathways which focus on protecting the international spread of disease to state economies, rather than protecting those who are most at risk. As such, the state-based structure of global health security provides the fault-line for global health security and women. This book highlights the ways in which women are disadvantaged by global health security policy, through engagement with feminist security studies concepts of visibility; social and stratified reproduction; intersectionality; and structural violence. It argues that it was no coincidence that poor, black women living in low quality housing were the most affected by the Zika outbreak and will continue to be so, until global health security is gender mainstreamed. More broadly, I ask what would global health policy look like if it were to take gender seriously, and how would this impact global disease control sustainability?"--




Comprehensive Guidelines for Prevention and Control of Dengue and Dengue Haemorrhagic Fever


Book Description

Dengue Fever is the fastest emerging arboviral infection with major public health consequences for millions of people around the world, and in particular the South-East Asia region. These regional guidelines were extensively revised, updated and expanded with the focus on new and additional topics of current relevance to the populations of the region. They are intended to provide guidance to national and local-level program managers and public health officials, as well as stakeholders, including health practitioners, laboratory personnel and multisectoral partners, in strategic planning, implementation, monitoring and evaluation, and strengthening the response to dengue prevention and control in their countries. Scientists and researchers involved in vaccine and antiviral drug development will also find crucial baseline information in this publication.




Improving Health Care in Low- and Middle-Income Countries


Book Description

This open access book is a collection of 12 case studies capturing decades of experience improving health care and outcomes in low- and middle-income countries. Each case study is written by healthcare managers and providers who have implemented health improvement projects using quality improvement methodology, with analysis from global health experts on the practical application of improvement methods. The book shows how frontline providers in health and social services can identify gaps in care, propose changes to address those gaps, and test the effectiveness of their changes in order to improve health processes and outcomes. The chapters feature cases that provide real-life examples of the challenges, solutions, and benefits of improving healthcare quality and clearly demonstrate for readers what quality improvement looks like in practice:Addressing Behavior Change in Maternal, Neonatal, and Child Health with Quality Improvement and Collaborative Learning Methods in GuatemalaHaiti’s National HIV Quality Management Program and the Implementation of an Electronic Medical Record to Drive Improvement in Patient CareScaling Up a Quality Improvement Initiative: Lessons from Chamba District, IndiaPromoting Rational Use of Antibiotics in the Kyrgyz RepublicStrengthening Services for Most Vulnerable Children through Quality Improvement Approaches in a Community Setting: The Case of Bagamoyo District, TanzaniaImproving HIV Counselling and Testing in Tuberculosis Service Delivery in Ukraine: Profile of a Pilot Quality Improvement Team and Its Scale‐Up JourneyImproving Health Care in Low- and Middle-Income Countries: A Case Book will find an engaged audience among healthcare providers and administrators implementing and managing improvement projects at Ministries of Health in low- to middle-income countries. The book also aims to be a useful reference for government donor agencies, their implementing partners, and other high-level decision makers, and can be used as a course text in schools of public health, public policy, medicine, and development. ACKNOWLEDGMENT:This work was conducted under the USAID Applying Science to Strengthen and Improve Systems (ASSIST) Project, USAID Award No. AID-OAA-A-12-00101, which is made possible by the generous support of the American people through the U.S. Agency for International Development (USAID). DISCLAIMER:The contents of this book are the sole responsibility of the Editor(s) and do not necessarily reflect the views of USAID or the United States Government. div=""^




Designing Effective Messages to Promote Future Zika Vaccine Uptake


Book Description

The Zika virus is associated with the devastating birth defect microcephaly, and while a vaccine was not yet available in early-2017, several were under development. It is imperative to identify effective communication strategies to promote uptake of a new vaccine, particularly among women of reproductive age. Moreover, though the Zika outbreak has received much social media attention, little is known about these conversations on Instagram. The purpose of this dissertation, therefore, was to understand current Zika-focused communication on Instagram and to inform effective communication strategies to promote future Zika vaccine uptake intent. The study aims were: (1) explore Zika conversations on Instagram; (2) determine effective message characteristics to increase Zika vaccine uptake intent; and (3) explore salient demographic, healthcare, and psychosocial factors related to Zika vaccine uptake intent. A content analysis of 1,000 Zika-focused Instagram posts, found that these messages primarily focus on perceived threat constructs, yet they elicited little engagement. In addition, 10% of all Instagram posts mentioned conspiracy theories, and these messages elicited high engagement. A 2x2 online experiment tested the effect of message framing and visual type on Zika vaccine uptake intent. The 339 participants - all women of reproductive age - each were exposed to one of four messages (gain vs. loss-framed, and infographic vs. photo). There was no interaction effect of framing and visual type (p=.116), nor main effect of either framing (p=.185) or visual type (p=.724) on vaccine uptake intent. When testing the effect of these variables on those known to be predictors of behavioral intent, gain-framed messages were associated with higher subjective norms, perceived benefits, and self-efficacy. Data from the same online survey was used to examine whether demographics, healthcare-related variables, and psychosocial variables predict Zika vaccine uptake intent. Attitude (p




Dengue


Book Description

This publication is intended to contribute to prevention and control of the morbidity and mortality associated with dengue and to serve as an authoritative reference source for health workers and researchers. These guidelines are not intended to replace national guidelines but to assist in the development of national or regional guidelines. They are expected to remain valid for five years (until 2014), although developments in research could change their validity.--Publisher's description.




Arboviruses


Book Description

Arthropod-borne viruses (arboviruses) are the causative agents of significant morbidity and mortality among humans and domestic animals globally. They are maintained in complex biological life cycles, involving a primary vertebrate host and a primary arthropod vector. While all known arboviruses are zoonotic pathogens, their emergence as human pathogens is associated with dramatic increases of human population growth leading to uncontrolled urbanization, changes in land and water use, changes in agricultural practices, new irrigation systems and deforestation. This book brings together a panel of expert arbovirologists to produce a timely review of the rapidly expanding arbovirus research literature. In addition authors identify the most pressing questions that remain to be answered, thus providing a stimulus for future research. Topics include: taxonomy, genome organization, virus-host and virus-vector interactions, evolutionary history, role of vertical transmission in arbovirus maintenance and evolution, epidemiology, arbovirus replication, pathogenesis, arbovirus diagnostics and control, including vaccines, novel anti-viral drugs, RNA interference and genetically modified vectors. Essential reading for every arbovirologist and highly recommended for all virologists and public health officials. [Subject: Microbiology, Life Science, Arbovirology, Virology, Taxonomy, Epidemiology]