A Line of Blood


Book Description

In one of the most entertaining and twisty thrillers of the year a London family, a mother, father and young son, must deal with the murder of their secretive next door neighbor and the intrusive police investigation that follows. Readers will be faced with ever shifting and increasingly frightening suspicions that one or all of them had something to do with it. Alex Mercer loves his family more than anything. His wife Millicent and their precocious eleven-year-old son Max are everything to him, his little tribe. When he is with them all is right with the world. But when he and Max find their next door neighbour dead in his bathtub, their lives are suddenly and irrevocably changed. Max is surprisingly fascinated by the dead body, and Alex is understandably anxious about how Max will react later, once he takes it all in. And Alex is increasingly impatient for the police to conclude their investigation and call this the suicide that it so clearly was. But as new information surfaces, it becomes clear that there is more to this than anyone is saying... Why was the neighbour charging his home improvements to the Mercers’ address? How did Millicent’s bracelet end up in his apartment? And why, in fact, did Max lead his father into the house on the quiet summer night that they found the corpse? As suspicion grows between the three, the once close-knit family starts to disintegrate. Is Alex really the loving husband we believe him to be? And where is Millicent really going when she disappears for hours, walking the parks of London, stewing over something that she can’t forget? Each of them is suffering. Each has something to hide. And as each questions how well they really know each other, they must decide how far they’ll go to protect themselves-and each other-from investigators who are watching every move they make. Just waiting for someone to make a mistake.




Vascular Biology of the Placenta


Book Description

The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.




Regulation of Coronary Blood Flow


Book Description

Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.




Regulation of Tissue Oxygenation, Second Edition


Book Description

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and blood, the carrier of oxygen within these components of the cardiorespiratory system. The respiratory system takes oxygen from the atmosphere and transports it by diffusion from the air in the alveoli to the blood flowing through the pulmonary capillaries. The cardiovascular system then moves the oxygenated blood from the heart to the microcirculation of the various organs by convection, where oxygen is released from hemoglobin in the red blood cells and moves to the parenchymal cells of each tissue by diffusion. Oxygen that has diffused into cells is then utilized in the mitochondria to produce adenosine triphosphate (ATP), the energy currency of all cells. The mitochondria are able to produce ATP until the oxygen tension or PO2 on the cell surface falls to a critical level of about 4–5 mm Hg. Thus, in order to meet the energetic needs of cells, it is important to maintain a continuous supply of oxygen to the mitochondria at or above the critical PO2 . In order to accomplish this desired outcome, the cardiorespiratory system, including the blood, must be capable of regulation to ensure survival of all tissues under a wide range of circumstances. The purpose of this presentation is to provide basic information about the operation and regulation of the cardiovascular and respiratory systems, as well as the properties of the blood and parenchymal cells, so that a fundamental understanding of the regulation of tissue oxygenation is achieved.




Anatomy and Physiology


Book Description







Blood Donor Counselling


Book Description

Individuals who donate their blood provide a unique and precious gift in an act of human solidarity. In order to donate blood, prospective donors should be in good health and free from any infections that can be transmitted through transfusion. Most blood donors perceive themselves to be healthy, but some are unsuitable to donate blood due to the potential risk of compromising or worsening their own health or the risk of transmission of infections to patients. Blood transfusion services (BTS) have a duty of care towards blood donors as well as to the recipients of transfusion. This duty of care extends to prospective donors who are deferred from donation--whether on a temporary or permanent basis--as well as those who donate blood and are subsequently found to have unusual or abnormal test results. BTS have a responsibility to confirm test results and provide information, counseling and support to enable these individuals to understand and respond to unexpected information about their health or risk status. Counseling is part of the spectrum of care that a BTS should be able to provide to blood donors--including referral to medical practitioners or specialist clinical services. Pre-donation counseling was recognized as one element of the strategy to reduce and, if possible, prevent the donation of blood by individuals who might be at risk for HIV and other TTI including hepatitis B and C viruses as well as to inform the donor of the donation process and testing of blood for HIV. Post-donation counseling was acknowledged to be a necessary element of donor management as an adjunct to informing donors of unusual or abnormal test results. Blood donor counseling by trained specialist staff is now considered to be a key component of the blood system in most countries with a well-developed blood transfusion service. It may be required at a number of stages in the blood donation process or following blood screening and should be available at any point at which the BTS has an interface with donors. In many countries, however, blood donor counseling is not yet available in a structured way. Blood Donor Counselling: Implementation Guidelines has therefore been developed to provide guidance to blood transfusion services that have not yet established donor counseling programs.