› › A Comprehensive Text Book On Self Emulsifying Drug Delivery Systems

A Comprehensive Text Book on Self-emulsifying Drug Delivery Systems

Author : Deepak Kaushik

Publisher : Bentham Science Publishers

Page : 211 pages

File Size : 17,26 MB

Release : 2021-07-01

Category : Medical

ISBN : 981499801X

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Book Description

This text book is a guide for pharmaceutical academics (students and teachers) as well as industry professionals learning about drug delivery and formulation. Chapters presents comprehensive information about self-emulsifying formulations by providing an in-depth understanding of the basic concepts and formulation mechanisms. This information is supplemented by details about current research and development in this field. Readers will learn about the types of self-emulsifying drug delivery systems, evaluation parameters and digestion models, among other topics. Key Features: - 9 chapters organized in a reader-friendly layout - complete guide on self-emulsifying drug delivery formulations, including lipid based systems, SMEDOs, surfactants, and oral dosage forms - includes basic concepts and current developments in research and industrial applications - presents information on conventional and herbal formulations - references for further reading



Drug Delivery Strategies for Poorly Water-Soluble Drugs

Author : Dionysios Douroumis

Publisher : John Wiley & Sons

Page : 543 pages

File Size : 34,23 MB

Release : 2012-12-19

Category : Science

ISBN : 1118444671

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Book Description

Many newly proposed drugs suffer from poor water solubility, thus presenting major hurdles in the design of suitable formulations for administration to patients. Consequently, the development of techniques and materials to overcome these hurdles is a major area of research in pharmaceutical companies. Drug Delivery Strategies for Poorly Water-Soluble Drugs provides a comprehensive overview of currently used formulation strategies for hydrophobic drugs, including liposome formulation, cyclodextrin drug carriers, solid lipid nanoparticles, polymeric drug encapsulation delivery systems, self–microemulsifying drug delivery systems, nanocrystals, hydrosol colloidal dispersions, microemulsions, solid dispersions, cosolvent use, dendrimers, polymer- drug conjugates, polymeric micelles, and mesoporous silica nanoparticles. For each approach the book discusses the main instrumentation, operation principles and theoretical background, with a focus on critical formulation features and clinical studies. Finally, the book includes some recent and novel applications, scale-up considerations and regulatory issues. Drug Delivery Strategies for Poorly Water-Soluble Drugs is an essential multidisciplinary guide to this important area of drug formulation for researchers in industry and academia working in drug delivery, polymers and biomaterials.



Lipid Nanocarriers for Drug Targeting

Author : Alexandru Mihai Grumezescu

Publisher : William Andrew

Page : 676 pages

File Size : 14,89 MB

Release : 2018-04-16

Category : Science

ISBN : 012813688X

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Book Description

Lipid Nanocarriers for Drug Targeting presents recent advances in the area of lipid nanocarriers. The book focuses on cationic lipid nanocarriers, solid lipid nanocarriers, liposomes, thermosensitive vesicles, and cubosomes, with applications in phototherapy, cosmetic and others. As the first book related to lipid nanocarriers and their direct implication in pharmaceutical nanotechnology, this important reference resource is ideal for biomaterials scientists and those working in the medical and pharmaceutical industries that want to learn more on how lipids can be used to create more effective drug delivery systems. - Highlights the most commonly used types of lipid nanocarriers and explains how they are applied in pharmacy - Shows how lipid nanocarriers are used in different types of treatment, including oral medicine, skin repair and cancer treatment - Assesses the pros and cons of using different lipid nanocarriers for different therapies



Oral Bioavailability

Author : Xiaoling Li

Publisher : John Wiley & Sons

Page : 875 pages

File Size : 50,57 MB

Release : 2011-08-04

Category : Medical

ISBN : 1118067584

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Book Description

Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications is designed to help chemists, biologists, life science researchers, pharmaceutical scientists, pharmacologists, clinicians, and graduate and students become familiar with the fundamentals and practices of the science of oral bioavailability. The difference in rate and extent between a drug taken orally and the actual amount of a drug reaching the circulatory system, oral bioavailability is an essential parameter for determining the efficacy and adverse effects of new and developing medications, as well as finding an optimal dosing regimen. This book provides a much-needed one-stop resource to help readers better understand and appreciate the many facets and complex problems of oral bioavailability, including the basic barriers to oral bioavailability, the methods used to determine relevant parameters, and the challenges of drug delivery. In addition, this comprehensive book discusses biological and physicochemical methods for improving bioavailability, integrates physicochemistry with physiology and molecular biology, and includes several state-of-the-art technologies and approaches Caco-2 cell culture model, MDCK, and other related cell culture models which are used to study the science of oral bioavailability.



Organic Polymers in Energy-Environmental Applications

Author : Ramesh Oraon

Publisher : John Wiley & Sons

Page : 626 pages

File Size : 34,10 MB

Release : 2024-11-19

Category : Science

ISBN : 3527352376

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Book Description

Enables readers to understand core concepts behind organic polymers and their multifunctional applications, focusing on environmental and sustainable applications Organic Polymers in Energy-Environmental Applications provides comprehensive coverage of polymerization and functionalization of organic polymers, followed by innovative approaches, sustainable technologies, and solutions for energy and environmental applications, including environmental remediation, energy storage, corrosion protection, and more. Edited by five highly qualified academics with significant experience in the field, Organic Polymers in Energy-Environmental Applications includes discussion on: Characteristics and emerging trends of organic polymers, and organic polymers in imaging industries and curable coatings Antifouling technology based on organic polymers and wearable technology featuring multifunctional sensor arrays in biomedicine Organic bio-adhesive polymers in filter technology, nano-architectured organic polymers, and market dynamics of organic polymer-based technologies Organic and inorganic modifications of polymers, pollutant removal via organic polymers, and biodegradable organic polymers Life cycle assessment of organic polymers, applications of organic polymers in agriculture, and future outlooks of the field With complete coverage of organic polymers, a topic of high interest due to their numerous practical applications ranging from membranes to super capacitors, Organic Polymers in Energy-Environmental Applications is an essential resource for polymer and environmental chemists, materials scientists, and all other related researchers and professionals interested in the subject.



Pharmaceutical Quality by Design

Author : Sarwar Beg

Publisher : Academic Press

Page : 450 pages

File Size : 24,73 MB

Release : 2019-03-27

Category : Medical

ISBN : 0128163720

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Book Description

Pharmaceutical Quality by Design: Principles and Applications discusses the Quality by Design (QbD) concept implemented by regulatory agencies to ensure the development of a consistent and high-quality pharmaceutical product that safely provides the maximum therapeutic benefit to patients. The book walks readers through the QbD framework by covering the fundamental principles of QbD, the current regulatory requirements, and the applications of QbD at various stages of pharmaceutical product development, including drug substance and excipient development, analytical development, formulation development, dissolution testing, manufacturing, stability studies, bioequivalence testing, risk and assessment, and clinical trials. Contributions from global leaders in QbD provide specific insight in its application in a diversity of pharmaceutical products, including nanopharmaceuticals, biopharmaceuticals, and vaccines. The inclusion of illustrations, practical examples, and case studies makes this book a useful reference guide to pharmaceutical scientists and researchers who are engaged in the formulation of various delivery systems and the analysis of pharmaceutical product development and drug manufacturing process. - Discusses vital QbD precepts and fundamental aspects of QbD implementation in the pharma, biopharma and biotechnology industries - Provides helpful illustrations, practical examples and research case studies to explain QbD concepts to readers - Includes contributions from global leaders and experts from academia, industry and regulatory agencies



Advances in Drug Delivery

Author : V a Jithan

Publisher :

Page : 444 pages

File Size : 17,98 MB

Release : 2017-10-05

Category :

ISBN : 9789386819581

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Book Description

Advances in drug delivery is a very specialized area of pharmaceutics where in the principles and technologies applied in the formulation and development, are emerging and progressing. Advances in Drug Delivery incorporates latest information regarding various subjects of drug delivery. Drug delivery is a broad term encompassing various means of achieving optimum drug reach to the target tissue, cell or the receptor. Several preformulation, formulation, biopharmaceutical, targeting and pharmacokinetic principles are applied in drug delivery. Research and development in drug delivery is increasing at a rapid pace throughout the world. The need for increased efficiency of new therapies and reduction in future public health expenses will definitely bolster this area of research and development. In order to meet this demand, many well known and efficiently applied drugs will be reformulated in new drug delivery systems that can be value-added for optimized therapeutic activity. Further, several new molecules are being generated by medicinal chemists and their formulation is not any more empirical but it is now very systematic. The aim of book is to enlighten pharmaceutical scientists all around the world with latest information on the topics which are involved in cutting edge growth of pharma research and industry. Highlights - A chapter on hot melt extrusion is included - Included a chapter on oral disintegrating tablets - a value addition product - Caters to all those who aim to achieve higher objectives in drug delivery



Nanoemulsions

Author : Seid Mahdi Jafari

Publisher : Academic Press

Page : 665 pages

File Size : 10,4 MB

Release : 2018-02-24

Category : Technology & Engineering

ISBN : 0128118393

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Book Description

Nanoemulsions: Formulation, Applications, and Characterization provides detailed information on the production, application and characterization of food nanoemulsion as presented by experts who share a wealth of experience. Those involved in the nutraceutical, pharmaceutical and cosmetic industries will find this a useful reference as it addresses findings related to different preparation and formulation methods of nanoemulsions and their application in different fields and products. As the last decade has seen a major shift from conventional emulsification processes towards nanoemulsions that both increase the efficiency and stability of emulsions and improve targeted drug and nutraceutical delivery, this book is a timely resource. - Summarizes general aspects of food nanoemulsions and their formulation - Provides detailed information on the production, application, and characterization of food nanoemulsion - Reveals the potential of nanoemulsions, as well as their novel applications in functional foods, nutraceutical products, delivery systems, and cosmetic formulations - Explains preparation of nanoemulsions by both low- and high-energy methods



Advanced Drug Delivery Systems in the Management of Cancer

Author : Kamal Dua

Publisher : Elsevier

Page : 574 pages

File Size : 35,37 MB

Release : 2021-06-24

Category : Science

ISBN : 0323900798

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Book Description

Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the treatment of cancer. Cancer therapy remains one of the greatest challenges in modern medicine, as successful treatment requires the elimination of malignant cells that are closely related to normal cells within the body. Advanced drug delivery systems are carriers for a wide range of pharmacotherapies used in many applications, including cancer treatment. The use of such carrier systems in cancer treatment is growing rapidly as they help overcome the limitations associated with conventional drug delivery systems. Some of the conventional limitations that these advanced drug delivery systems help overcome include nonspecific targeting, systemic toxicity, poor oral bioavailability, reduced efficacy, and low therapeutic index. This book begins with a brief introduction to cancer biology. This is followed by an overview of the current landscape in pharmacotherapy for the cancer management. The need for advanced drug delivery systems in oncology and cancer treatment is established, and the systems that can be used for several specific cancers are discussed. Several chapters of the book are devoted to discussing the latest technologies and advances in nanotechnology. These include practical solutions on how to design a more effective nanocarrier for the drugs used in cancer therapeutics. Each chapter is written with the goal of informing readers about the latest advancements in drug delivery system technologies while reinforcing understanding through various detailed tables, figures, and illustrations. Advanced Drug Delivery Systems in the Management of Cancer is a valuable resource for anyone working in the fields of cancer biology and drug delivery, whether in academia, research, or industry. The book will be especially useful for researchers in drug formulation and drug delivery as well as for biological and translational researchers working in the field of cancer. - Presents an overview of the recent perspectives and challenges within the management and diagnosis of cancer - Provides insights into how advanced drug delivery systems can effectively be used in the management of a wide range of cancers - Includes up-to-date information on diagnostic methods and treatment strategies using controlled drug delivery systems



Current Technologies To Increase The Transdermal Delivery Of Drugs

Author : José Juan Escobar-Chávez

Publisher : Bentham Science Publishers

Page : 155 pages

File Size : 42,38 MB

Release : 2010

Category : Medical

ISBN : 1608051919

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Book Description

This e-book provides an overview of current technologies used to increase the topical/transdermal delivery of drugs, its protocols, advantages and limitations. It includes exclusive chapters on chemical enhancers, Iontophoresis, Sonophoresis, Electroporation, Microneedles and the more recent use of micro/nanoparticles to deliver drugs throughout the skin. The e-book's generalized approach on the topic is aimed to be helpful in drug discovery, drug delivery and toxicological research and to provide a broader perspective on the topic to readers with respect to current literature available on the.