A History of Poliomyelitis


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A History of Poliomyelitis


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Polio


Book Description

In 1988, the World Health Organization launched a twelve-year campaign to wipe out polio. Thirty years and several billion dollars over budget later, the campaign grinds on, vaccinating millions of children and hoping that each new year might see an end to the disease. But success remains elusive, against a surprisingly resilient virus, an unexpectedly weak vaccine and the vagaries of global politics, meeting with indifference from governments and populations alike. How did an innocuous campaign to rid the world of a crippling disease become a hostage of geopolitics? Why do parents refuse to vaccinate their children against polio? And why have poorly paid door-to-door healthworkers been assassinated? Thomas Abraham reports on the ground in search of answers.







Adverse Events Associated with Childhood Vaccines


Book Description

Childhood immunization is one of the major public health measures of the 20th century and is now receiving special attention from the Clinton administration. At the same time, some parents and health professionals are questioning the safety of vaccines because of the occurrence of rare adverse events after immunization. This volume provides the most thorough literature review available about links between common childhood vaccinesâ€"tetanus, diphtheria, measles, mumps, polio, Haemophilus influenzae b, and hepatitis Bâ€"and specific types of disorders or death. The authors discuss approaches to evidence and causality and examine the consequencesâ€"neurologic and immunologic disorders and deathâ€"linked with immunization. Discussion also includes background information on the development of the vaccines and details about the case reports, clinical trials, and other evidence associating each vaccine with specific disorders. This comprehensive volume will be an important resource to anyone concerned about the immunization controversy: public health officials, pediatricians, attorneys, researchers, and parents.




The Polio Years in Texas


Book Description

From the 1930s to the 1950s, in response to the rising epidemic of paralytic poliomyelitis (polio), Texas researchers led a wave of discoveries in virology, rehabilitative therapies, and the modern intensive care unit that transformed the field nationally. The disease threatened the lives of children and adults in the United States, especially in the South, arousing the same kind of fear more recently associated with AIDS and other dread diseases. Houston and Harris County, Texas, had the second-highest rate of infection in the nation, and the rest of the Texas Gulf Coast was particularly hard-hit by this debilitating illness. At the time, little was known, but eventually the medical responses to polio changed the medical landscape forever. Polio also had a sweeping cultural and societal effect. It engendered fearful responses from parents trying to keep children safe from its ravages and an all-out public information blitz aimed at helping a frightened population protect itself. The disease exacted a very real toll on the families, friends, healthcare resources, and social fabric of those who contracted the disease and endured its acute, convalescent, and rehabilitation phases. In The Polio Years in Texas, Heather Green Wooten draws on extensive archival research as well as interviews conducted over a five-year period with Texas polio survivors and their families. This is a detailed and intensely human account of not only the epidemics that swept Texas during the polio years, but also of the continuing aftermath of the disease for those who are still living with its effects. Public health and medical professionals, historians, and interested general readers will derive deep and lasting benefits from reading The Polio Years in Texas.




Polio Across the Iron Curtain


Book Description

Through the lens of polio, Dóra Vargha looks anew at international health, communism and Cold War politics. This title is also available as Open Access.




Dirt and Disease


Book Description

Dirt and Disease is a social, cultural, and medical history of the polio epidemic in the United States. Naomi Rogers focuses on the early years from 1900 to 1920, and continues the story to the present. She explores how scientists, physicians, patients, and their families explained the appearance and spread of polio and how they tried to cope with it. Rogers frames this study of polio within a set of larger questions about health and disease in twentieth-century American culture.




The Cutter Incident


Book Description

Vaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, thathas led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases.




Splendid Solution


Book Description

The compelling true story of Dr. Jonas Salk's quest to develop a vaccine for polio. In 1916, the United States was hit with one of the worst polio epidemics in history. The disease was a terrifying enigma: striking out of nowhere, it afflicted tens of thousands of children and left them—literally overnight—paralyzed. Others it simply killed. At the same time, a child named Jonas Salk was born.... When Franklin Delano Roosevelt was diagnosed with polio shortly before assuming the Presidency, Salk was given an impetus to study this deadly illness. After assisting in the creation of an influenza vaccine, Salk took up the challenge. His progress in combating the virus was hindered by the politics of medicine and by a rival researcher determined to discredit his proposed solution. But Salk's perseverance made history—and for close to seventy years his vaccine has saved countless lives, bringing humanity close to eradicating polio throughout the world. Splendid Solution chronicles Dr. Salk's race against time to achieve an unparalleled breakthrough that made him a cultural hero and icon of modern medicine.