Author : Richard E Frye
Publisher : Mdpi AG
Page : 0 pages
File Size : 23,93 MB
Release : 2022-08-16
Category :
ISBN : 9783036532219
This collection of articles provides an overview of the current and future methods for applying a personalized medicine approach to the diagnosis, management, and treatment of autism spectrum disorder.
Author : Lidia V. Gabis
Publisher : Frontiers Media SA
Page : 176 pages
File Size : 40,57 MB
Release : 2022-02-15
Category : Medical
ISBN : 2889716775
Author : David Quentin Beversdorf
Publisher : Frontiers Media SA
Page : 153 pages
File Size : 31,96 MB
Release : 2023-04-17
Category : Medical
ISBN : 2832515681
Many therapeutic interventions for autism spectrum disorder fail when they are examined in a clinical trial. Frequently, there is a subset of patients that responds very well to the intervention, while others do not, and the overall result does not yield a positive result. As autism spectrum disorder is highly heterogeneous in its underlying genetics and other etiological risk factors, as well as its heterogeneous phenotypic manifestation, this variability in response to any specific treatment is not entirely surprising. However, it remains a challenge to meaningfully subtype this heterogeneity for targeted treatment. The purpose of this research topic is to solicit articles that address the heterogeneity in autism spectrum disorder in a manner that may meaningfully contribute to targeted treatment approaches. Studies that address the heterogeneity of autism that could theoretically lead to targeted treatment, and studies that more directly address the use of a marker in association with response to a treatment, are both aspects that will contribute to this purpose. It is hoped that this Research Topic will yield articles that can help advance the field towards precision medicine in autism spectrum disorders. Manuscripts that contribute to the specification of the heterogeneity of autism spectrum disorder in a manner that could theoretically lead to targeted treatment would be appropriate for this research topic. Additionally, articles that utilize subtyping in relation to response to treatment would be appropriate for this research topic.
Author : M. Mohamed Essa
Publisher : Springer Nature
Page : 700 pages
File Size : 10,74 MB
Release : 2020-01-31
Category : Medical
ISBN : 3030304027
The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.
Author : Martin J. Lubetsky
Publisher : OUP USA
Page : 355 pages
File Size : 17,95 MB
Release : 2011-06-27
Category : Medical
ISBN : 0199753857
Autism Spectrum Disorder of the Pittsburgh Pocket Psychiatry Series highlights current key topics for this developmental neurobiological disorder: early identification and diagnosis; medical, psychiatric, behavioral, social, educational and language evaluations and treatment approaches; genetics and neurobiology; and transition-age and adult services. This book incorporates practical clinical knowledge within a didactic framework to provide a comprehensive overview of Autism Spectrum Disorder (ASD) across the lifespan.
Author : Todd T. Eckdahl
Publisher : Momentum Press
Page : 95 pages
File Size : 29,66 MB
Release : 2018-04-09
Category : Science
ISBN : 1944749608
This book is an overview of autism spectrum disorder (ASD), an early childhood condition that affects 1 in 68 children in the United States, and an estimated 1 to 2 percent of children worldwide. ASD causes impaired social skills, communication problems, and repetitive behaviors. The severity of ASD symptoms varies widely, ranging from mild effects with minimal impacts on functionality to severe effects that interfere with functionality and can prevent independent living. ASD is a complex trait disease caused by mutation of multiple ASD susceptibility genes, but it also occurs as part of monogenic genetic syndromes. Genetic testing for ASD is described in the book, and examples of ASD susceptibility genes. No treatments are available for the core symptoms of ASD, but the book describes therapies and drug treatments that can modulate them and address some of the health complications of ASD. The book presents new ASD biomarkers that can be used for better diagnosis and explores the hopeful prospect of personalized medicine for ASD.
Author : Neophytos Papaneophytou
Publisher : Academic Press
Page : 592 pages
File Size : 37,96 MB
Release : 2021-06-10
Category : Psychology
ISBN : 0323859771
Emerging Programs for Autism Spectrum Disorder: Improving Communication, Behavior, and Family Dynamics brings forward a hybrid and a transdisciplinary methodology to identify methods used to diagnose, treat, and manage those with autism within personal and social constructs and values building exemplary international experiences from across the globe. Luminary experts offer their superb level of expertise through their research, experience, and clinical work. The book addresses all the aspects of care, lifespan, and lifestyle issues from treatment to living. It will emphasize issues related to neurodiversity, individuality, best practices, and support of people on the Autism Spectrum and their families. In addition, this book includes specific case studies, highlighting family experiences and the application of best practices by therapists thereof. Provides a multidisciplinary approach of the diagnosis, management and treatment of autism spectrum disorders Includes specific case studies highlighting family experiences Emphasizes issues related to neurodiversity, individuality and improving quality of life
Author : Ellen Giarelli
Publisher : Charles C Thomas Publisher
Page : 423 pages
File Size : 28,5 MB
Release : 2016-01-27
Category : Family & Relationships
ISBN : 0398091013
People with autism spectrum disorder may have unique development challenges, but they face a range of health issues like all people, and many of these may be compounded by an ASD. This book provides the tools and information so the health care professional can think differently about caring for this patient and see through his or her eyes. The presentations of 28 contributors share the importance of early, continuous, coordinated, and individualized care that is integrated into the existing health care system. Examples of models and policies that have improved the access, experience, and outcomes for patients with ASD are shared. In addition, the importance of continuous quality improvement through data collection and monitoring of outcomes is emphasized. This information is essential for addressing the capacity crisis now in providing routine, specialized, and emergency care for individuals with ASD. Some of the major topics discussed include: the epidemiology of autism spectrum disorder; facilitating the role of parents in management and advocacy; the impact of the sensory environment on care; medications for the treatment of psychiatric comorbidities; frameworks to guide practice and research with patients; building a home for acute care needs; assisting parents in adapting and making decisions regarding treatment options; integrating genetic testing into health care; educating nurses with faculty and curricular issues; emergency medicine and improving service; physical therapy to promote health, function, and community participation; using big data to direct quality improvement; and monitoring patient outcomes in research and policy outcomes. This significant volume brings together a wealth of expertise with information and strategies across the lifespan for individuals with autism spectrum disorder.
Author : Andreas M. Grabrucker
Publisher :
Page : 117 pages
File Size : 11,38 MB
Release : 2021
Category :
ISBN :
Autism spectrum disorders are developmental disorders. Individuals with autism spectrum disorders develop differently. These differences are usually present in social interaction, communication, and sensory processing, and become visible through a wide variety of behavioral responses that differ from individuals without autism spectrum disorders. Despite significant research efforts, the exact causes of autism spectrum disorders remain poorly understood; however, researchers have gained extensive insights into possible pathomechanisms, even at the molecular level of cells. Many diagnostic criteria have been developed, adapted, and improved. The eight chapters in this book highlight the current state-of-the-art in many areas of autism spectrum disorders. Chapter 1 provides an overview of the epidemiology of autism spectrum disorders and the current knowledge of the underlying pathogenic mechanisms. Chapter 2 summarizes the diagnostic criteria and procedures and highlights present and upcoming therapeutic strategies. Chapter 3 reviews the adverse events and trauma in people with autism spectrum disorders. Chapters 4 and 5 focus on atypical sensory processing, and Chapter 6 discusses the genetic overlap of autism spectrum disorders with other neuropsychiatric disorders such as attention deficit hyperactivity disorder (ADHD), depression, and schizophrenia. Chapter 7 focuses on the contribution of abnormalities in mitochondria, and chapter 8 discusses gut-brain interactions and a potential role for microbiota in autism spectrum disorders. This book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.
Author : Bernhard Baune
Publisher : Academic Press
Page : 604 pages
File Size : 22,1 MB
Release : 2019-10-16
Category : Medical
ISBN : 0128131772
Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective
