A Picture is Worth a Thousand Tables


Book Description

This book is devoted to the graphics of patient data: good graphs enabling straight¬forward and intuitive interpretation, efficient creation, and straightforward interpretation. We focus on easy access to graphics of patient data: the intention is to show a large variety of graphs for different phases of drug development, together with a description of what the graph shows, what type of data it uses, and what options there are. The main aim is to provide inspiration in form of a “graphics cookbook.” Many graphs provide creative ideas about what can be done. The book is not intended to be technical. It introduces general principles of good visualization to make readers understand the concepts, but the main focus is on the creativity and usefulness: readers are enabled to browse through the book to get ideas of how their own data can be analyzed graphically. For additional information visit Editor’s companion website: http://www.elmo.ch/doc/life-science-graphics/




Statistics


Book Description

An invaluable work for people who need to understand statistics and utilize their results. The book is not technical; its purpose is to teach the reader how to understand and apply statistics. Most of the examples are from education, but people in all fields using statistics will find this book indispensable. Written with great clarity, this is a first-rate statistics book for the non-statistician.




Writing with Sweet Clarity


Book Description

In this book, criminologist and experienced educator John E. Eck draws on decades of academic and professional writing experience to provide an analytical toolkit for clear professional writing. This book focuses on the essential objective of clarity, and addresses topics seldom addressed in other books, such as ethics beyond plagiarism; writing with co-authors; organizing complex ideas; using analytics to improve writing; crafting strong beginnings and endings; using examples and metaphors; and integrating tables, charts, and diagrams. As universities continue to demand writing-intensive courses in the social sciences, this book is indispensable in university settings and throughout a professional career. The reader will use the practical advice, examples, and exercises in this book to master a method for clear writing unimpaired by stereotypical academic jargon. The book will help both new and seasoned researchers seeking to translate their work into a clear and accessible presentation for both professional and lay audiences. Designed for and field-tested with graduate and advanced undergraduate students, this lively and easy-to-read book will work for courses taught in criminology, sociology, geography, and other social sciences, and will enable scholars to extend and broaden the impact of their research.




Graphical Data Analysis with R


Book Description

See How Graphics Reveal Information Graphical Data Analysis with R shows you what information you can gain from graphical displays. The book focuses on why you draw graphics to display data and which graphics to draw (and uses R to do so). All the datasets are available in R or one of its packages and the R code is available at rosuda.org/GDA. Graphical data analysis is useful for data cleaning, exploring data structure, detecting outliers and unusual groups, identifying trends and clusters, spotting local patterns, evaluating modelling output, and presenting results. This book guides you in choosing graphics and understanding what information you can glean from them. It can be used as a primary text in a graphical data analysis course or as a supplement in a statistics course. Colour graphics are used throughout.




Statistical Methods for Evaluating Safety in Medical Product Development


Book Description

This book gives professionals in clinical research valuable information on the challenging issues of the design, execution, and management of clinical trials, and how to resolve these issues effectively. It also provides understanding and practical guidance on the application of contemporary statistical methods to contemporary issues in safety evaluation during medical product development. Each chapter provides sufficient detail to the reader to undertake the design and analysis of experiments at various stages of product development, including comprehensive references to the relevant literature. Provides a guide to statistical methods and application in medical product development Assists readers in undertaking design and analysis of experiments at various stages of product development Features case studies throughout the book, as well as, SAS and R code




Quantitative Methods in Pharmaceutical Research and Development


Book Description

This contributed volume presents an overview of concepts, methods, and applications used in several quantitative areas of drug research, development, and marketing. Chapters bring together the theories and applications of various disciplines, allowing readers to learn more about quantitative fields, and to better recognize the differences between them. Because it provides a thorough overview, this will serve as a self-contained resource for readers interested in the pharmaceutical industry, and the quantitative methods that serve as its foundation. Specific disciplines covered include: Biostatistics Pharmacometrics Genomics Bioinformatics Pharmacoepidemiology Commercial analytics Operational analytics Quantitative Methods in Pharmaceutical Research and Development is ideal for undergraduate students interested in learning about real-world applications of quantitative methods, and the potential career options open to them. It will also be of interest to experts working in these areas.




Optimization Modelling Using R


Book Description

This book covers using R for doing optimization, a key area of operations research, which has been applied to virtually every industry. The focus is on linear and mixed integer optimization. It uses an algebraic modeling approach for creating formulations that pairs naturally with an algebraic implementation in R. With the rapid rise of interest in data analytics, a data analytics platform is key. Working technology and business professionals need an awareness of the tools and language of data analysis. R reduces the barrier to entry for people to start using data analytics tools. Philosophically, the book emphasizes creating formulations before going into implementation. Algebraic representation allows for clear understanding and generalization of large applications, and writing formulations is necessary to explain and convey the modeling decisions made. Appendix A introduces R. Mathematics is used at the level of subscripts and summations Refreshers are provided in Appendix B. This book: • Provides and explains code so examples are relatively clear and self-contained. • Emphasizes creating algebraic formulations before implementing. • Focuses on application rather than algorithmic details. • Embodies the philosophy of reproducible research. • Uses open-source tools to ensure access to powerful optimization tools. • Promotes open-source: all materials are available on the author’s github repository. • Demonstrates common debugging practices with a troubleshooting emphasis specific to optimization modeling using R. • Provides code readers can adapt to their own applications . This book can be used for graduate and undergraduate courses for students without a background in optimization and with varying mathematical backgrounds.




National Meeting


Book Description







Medical Product Safety Evaluation


Book Description

Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some frequently encountered issues and challenges in the design and analysis of safety studies are discussed with illustrative applications and examples. Medical Product Safety Evaluation: Biological Models and Statistical Methods presents cutting-edge biological models and statistical methods that are tailored to specific objectives and data types for safety analysis and benefit-risk assessment. Some frequently encountered issues and challenges in the design and analysis of safety studies are discussed with illustrative applications and examples. The book is designed not only for biopharmaceutical professionals, such as statisticians, safety specialists, pharmacovigilance experts, and pharmacoepidemiologists, who can use the book as self-learning materials or in short courses or training programs, but also for graduate students in statistics and biomedical data science for a one-semester course. Each chapter provides supplements and problems as more readings and exercises.