A Primer for Sampling Solids, Liquids, and Gases


Book Description

The ideas of Pierre Gy presented in lay terms, allowing concepts and principles to be easily grasped and applied.




Coulson and Richardson's Chemical Engineering


Book Description

Coulson and Richardson's Chemical Engineering: Volume 2A: Particulate Systems and Particle Technology, Sixth Edition, has been fully revised and updated to provide practitioners with an overview of chemical engineering, including clear explanations of theory and thorough coverage of practical applications, all supported by case studies. A worldwide team of contributors has pooled their experience to revise old content and add new content. The content has been updated to be more useful to practicing engineers. This complete reference to chemical engineering will support you throughout your career, as it covers every key chemical engineering topic. Fluid Flow, Heat Transfer and Mass Transfer has been developed from the series' volume 1, 6th edition. This volume covers the three main transport process of interest to chemical engineers: momentum transfer (fluid flow), heat transfer and mass transfer and the relationships between them. Particulate Systems and Particle Technology has been developed from the series' volume 2, 5th edition. This volume covers the properties of particulate systems, including the character of individual particles and their behavior in fluids. Sedimentation of particles, both singly and at high concentrations, flow in packed and fluidized beads and filtration are then examined. Separation Processes has been developed from the series' volume 2, 5th edition. This volume covers distillation and gas absorption, which illustrate applications of the fundamental principles of mass transfer. Several techniques—adsorption, ion exchange, chromatographic and membrane separations, and process intensification—are described. Chemical and Biochemical Reactors and Reaction Engineering has been developed from the series' volume 3, 3rd edition. - Features fully revised reference material converted from textbooks - Covers foundational to technical topics - Features emerging applications, numerical methods and computational tools




Field Sampling


Book Description

Written by a renowned professional with more than 30 years of experience in environmental sampling and analysis, this reference describes in unparalleled detail all the essential elements for the development and execution of a successful sampling plan at both contaminated and uncontaminated sites. The book covers presampling planning and decision-making, specific sampling situations, and correct sample labeling, and presents the framework and background for the sampling of any contaminated site. Presenting a wide variety of models, quality control procedures, and valuable troubleshooting methods, Field Sampling contains an abundance of topics never before covered in any other source.




Environmental Considerations Associated with Hydraulic Fracturing Operations


Book Description

A guide to environmental and communication issues related to fracking and the best approach to protect communities Environmental Considerations Associated with Hydraulic Fracturing Operations offers a much-needed resource that explores the complex challenges of fracking by providing an understanding of the environmental and communication issues that are inherent with hydraulic fracturing. The book balances the current scientific knowledge with the uncertainty and risks associated with hydraulic fracking. In addition, the authors offer targeted approaches for helping to keep communities safe. The authors include an overview of the historical development of hydraulic fracturing and the technology currently employed. The book also explores the risk, prevention, and mitigation factors that are associated with fracturing. The authors also include legal cases, regulatory issues, and data on the cost of recovery. The volume presents audit checklists for gathering critical information and documentation to support the reliability of the current environmental conditions related to fracking operations and the impact fracking can have on a community. This vital resource: Contains the technical information and mitigation recommendations for safety and environmental issues related to hydraulic fracturing Offers an historical overview of conventional and unconventional oil and gas drilling Explains the geologic and technical issues associated with fracking of tight sand and shale formulations Presents numerous case studies from the United States EPA and other agencies Discusses issues of co-produced waste water and induced seismicity from the injection of wastewater Written for environmental scientists, geologists, engineers, regulators, city planners, attorneys, foresters, wildlife biologists, and others, Environmental Considerations Associated with Hydraulic Fracturing Operations offers a comprehensive resource to the complex environmental and communication issues related to fracking.




Process Analytical Technology


Book Description

Process Analytical Technology explores the concepts of PAT and its application in the chemical and pharmaceutical industry from the point of view of the analytical chemist. In this new edition all of the original chapters have been updated and revised, and new chapters covering the important topics of sampling, NMR, fluorescence, and acoustic chemometrics have been added. Coverage includes: Implementation of Process Analytical Technologies UV-Visible Spectroscopy for On-line Analysis Infrared Spectroscopy for Process Analytical Applications Process Raman Spectroscopy Process NMR Spectrscopy: Technology and On-line Applications Fluorescent Sensing and Process Analytical Applications Chemometrics in Process Analytical Technology (PAT) On-Line PAT Applications of Spectroscopy in the Pharmaceutical Industry Future Trends for PAT for Increased Process Understanding and Growing Applications in Biomanufacturing NIR Chemical Imaging This volume is an important starting point for anyone wanting to implement PAT and is intended not only to assist a newcomer to the field but also to provide up-to-date information for those who practice process analytical chemistry and PAT. It is relevant for chemists, chemical and process engineers, and analytical chemists working on process development, scale-up and production in the pharmaceutical, fine and specialty chemicals industries, as well as for academic chemistry, chemical engineering, chemometrics and pharmaceutical science research groups focussing on PAT. Review from the First Edition “The book provides an excellent first port of call for anyone seeking material and discussions to understand the area better. It deserves to be found in every library that serves those who are active in the field of Process Analytical Technology.”—Current Engineering Practice




Pharmaceutical Dosage Forms - Tablets


Book Description

The ultimate goal of drug product development is to design a system that maximizes the therapeutic potential of the drug substance and facilitates its access to patients. Pharmaceutical Dosage Forms: Tablets, Third Edition is a comprehensive resource of the design, formulation, manufacture, and evaluation of the tablet dosage form, an




Progress in Chemometrics Research


Book Description

Chemometrics is the chemical discipline that uses mathematical, statistical and other methods employing formal logic: to design or select optimal measurement procedures and experiments, and -- to provide maximum relevant chemical information by analysing chemical data. Being conceived as a branch of analytical chemistry, chemometrics now is a general approach. It extracts relevant information out of measured data, regardless of their origin: chemical, physical, biological, etc. Chemometrics has been applied in different areas, and most successfully in multivariate calibration, pattern recognition, classification and discriminant analysis, multivariate modelling, and monitoring of processes. The main chemometric principle is a concept of hidden data structures that can be found using methods of multivariate data analysis. These are the well-known statistic tools such as partial least squares (PLS), soft independent modelling of class analogy (SIMCA), principal-component regression (PCR), wavelet analysis, and many others. Current activities of chemometricians fall into two main categories: (1) development of new methods for manipulating multivariate data and (2) new applications of the known chemometric techniques in different areas such as environment control, food industry, agriculture, medicine, and engineering.




The Analysis of Means


Book Description

The analysis of means (ANOM) is a graphical procedure used to quantify differences among treatment groups in a variety of experimental design and observational study situations. The ANOM decision chart allows one to easily draw conclusions and interpret results with respect to both statistical and practical significance. It is an excellent choice for multiple comparisons of means, rates, or proportions and can be used with both balanced and unbalanced data. Key advances in ANOM procedures that have appeared only in technical journals during the last 20 years are included in this first comprehensive modern treatment of the ANOM containing all of the needed information for practitioners to understand and apply ANOM. The Analysis of Means: A Graphical Method for Comparing Means, Rates, and Proportions contains examples from a wide variety of fields adapted from real-world applications and data with easy-to-follow, step-by-step instructions. It is front loaded, so potential ANOM users can find solutions to standard problems in the first five chapters. An appendix contains several SAS® examples showing the system's ANOM capabilities and how SAS was used to produce selected ANOM decision charts in the book.Given these features, the lack of any other book on ANOM, and the recent inclusion of ANOM in SAS, this book will be a welcome addition to practitioners' and statisticians' bookshelves, where it will serve both as a primer and reference.Applied statisticians, particularly consulting statisticians, will find that the graphical aspect of ANOM makes it easy to convey results to nonstatisticians. Industrial, process, and quality engineers will find that the ANOM decisions charts offer an ideal interface with management and can be instrumental in selling research conclusions. The ANOM procedures are great for comparing the rates and proportions found in managed health care settings, and for comparing outcomes in multiarm studies done by statistical researchers in medicine.




Design and Analysis of Gauge R&R Studies


Book Description

This book provides a protocol for conducting gauge repeatability and reproducibility (R&R) experiments. Such an experiment is required whenever a new test system is developed to monitor a manufacturing process. The protocol presented here is used to determine if the testing system is capable of monitoring the manufacturing process with the desired level of accuracy and precision. This protocol is not currently available in other books or technical reports. In addition to providing a protocol for testing a measurement system, the book presents an up-to-date summary of methods used to construct confidence intervals in normal-based random and mixed analysis of variance (ANOVA) models. Thus, this comprehensive book will be useful to scientists in all fields of application who wish to construct interval estimates for ANOVA model parameters. It includes approaches that can be applied to any ANOVA model, and because it contains detailed examples of all computations, practitioners will be able to easily apply the methods. The book describes methods for constructing two types of confidence intervals: modified large-sample (MLS) and generalized confidence intervals. Computer codes written in SAS and Excel are provided to perform the computations. Appendices are included for readers who are unfamiliar with confidence intervals or lack a basic understanding of random and mixed ANOVA models.




Recurrent Events Data Analysis for Product Repairs, Disease Recurrences, and Other Applications


Book Description

Survival data consist of a single event for each population unit, namely, end of life, which is modeled with a life distribution. However, many applications involve repeated-events data, where a unit may accumulate numerous events over time. This applied book provides practitioners with basic nonparametric methods for such data.