A short history of breast cancer


Book Description

The Third Breast Cancer Working Conference of the Breast Cancer Cooperative Group of the European Organization for Research on Treatment of Cancer, to be held in Amsterdam on April 27-29, 1983, was the principle motive for writing this book. It was felt that a short review of the main pathogenetic conceptions and therapeutic principles which have presented themselves with regard to mammary cancer in the course of Western history, might help to draw a more complete picture of where we stand today. It is not easy to decide which ideas, although discarded, deserve yet to be remembered and which authors from the past may be considered to be truly representative of the scientific climate of their age. Twenty centuries have produced quite a lot of ideas and the number of medical authors who advanced, or rejected, or modified, or revived them, is really uncountable. So the historian has to make a selec tion and choices are perforce subjective and open to criticism. In writing this book I tried to consult original sources in the original language as much as possible. These sources were not always strictly medical since I aimed at placing the problem of malignant breast disease - which might serve as a paradigm of cancer in general - in a somewhat wider context. For the history of medicine is not only a history of ideas, but also that of people, of institutions, of society.




The History and Mystery of Breast Cancer


Book Description

Breast cancer and its treatment is a terribly complex problem that involves all the intricacies of the human body, the anatomical and microscopic anatomy of the breast, the endocrine system, and bone metabolism, as well as the nature of malignant transformation. Even experts still have uncertainties. However, there is now an ethical and legal obligation for specialists to share their uncertainties with their patients when we are looking for informed consent before invasive procedures. Obsessive ruminations about the threat of breast cancer mean that few in the lay public know that breast cancer has slipped out of the top seven causes of death for women. Treatments for breast cancer might increase the risk of death from cardio-vascular disease, whilst, on the other hand, denying women in this age group hormone replacement therapy for the unjustified fear of breast cancer can impair their quality of life, cognitive function and bone mineral density. The totality of women’s health and expectation of life must always trump the single-issue fanatics who only view women as the sum of their two breasts. This is more than a self-help book, but should also be considered as introducing the history and mystery of breast cancer, from the time of the Ancient Egyptians to the modern era, as well as hopes for the future.




Bathsheba's Breast


Book Description

" ... An absorbing narrative history of breast cancer told through the heroic stories of women who have confronted the disease."--Back cover.




Radical


Book Description

Kate Pickert worked as a health-care journalist and knew medical treatment well, but it all changed when she was diagnosed with an aggressive type of breast cancer at age 35. Pickert used her journalistic skills to identify the cultural, scientific, and historical forces shaping the lives of breast-cancer patients in the modern age.




A short history of breast cancer


Book Description

The Third Breast Cancer Working Conference of the Breast Cancer Cooperative Group of the European Organization for Research on Treatment of Cancer, to be held in Amsterdam on April 27-29, 1983, was the principle motive for writing this book. It was feh that a short review of the main pathogenetic conceptions and therapeutic principles which have presented themselves with regard to mammary cancer in the Course of Western history , might help to draw a more complete picture of where we stand today. It is not easy to decide which ideas, although discarded, deserve yet to be remembered and which authors from the past may be considered to be truly representative of the scientific climate of their age. Twenty centuries have produced quite a lot of ideas and the number of medical authors who advanced, or rejected, or modified, or revived them, is really uncountable. So the historian has to make a selec tion and choices are perforce subjective and open to criticism. In writing this book I tried to consult original sources in the original language as much as possible. These sources were not always strictly medical since I aimed at placing the problem of malignant breast disease - which might serve as a paradigm of cancer in general - in a somewhat wider context. For the history of medicine is not only a history of ideas, but also that of people, of institutions, of society.




History of the Breast


Book Description

In this provocative, pioneering, and wholly engrossing cultural history, noted scholar Marilyn Yalom explores twenty-five thousand years of ideas, images, and perceptions of the female breast--in religion, psychology, politics, society, and the arts. Through the centuries, the breast has been laden with hugely powerful and contradictory meanings. There is the "good breast" of reverence and life, the breast that nourishes infants and entire communities, as depicted in ancient idols, fifteenth-century Italian Madonnas, and representations of equality in the French Revolution. Then there is the "bad breast" of Ezekiel's wanton harlots, Shakespeare's Lady Macbeth, and the torpedo-breasted dominatrix, symbolizing enticement and aggression. Yalom examines these contradictions--and illuminates the implications behind them. A fascinating, astute, and richly allusive journey from Paleolithic goddesses to modern day feminists, A History of the Breast is full of insight and surprises. As Yalom says, "I intend to make you think about women's breasts as you never have before." In this, she succeeds brilliantly.




The Breast Cancer Book


Book Description

"Providing comprehensive, current, and reliable information on breast cancer, this book, written by an experienced oncologist, a surgeon, and a breast cancer survivor, informs and inspires readers, wherever they are in the breast cancer experience. Patient stories, essays from medical specialists, and illustrations add clarity and insight"--




Her-2


Book Description

Two years after she underwent a mastectomy and chemotherapy, Barbara Bradfield's aggressive breast cancer had recurred and spread to her lungs. The outlook was grim. Then she took part in Genentech's clinical trials for a new drug. Five years later she remains cancer-free. Her-2 is the biography of Herceptin, the drug that provoked dramatic responses in Barbara Bradfield and other women in the trials and that offers promise for hundreds of thousands of breast cancer patients. Unlike chemotherapy or radiation, Herceptin has no disabling side effects. It works by inactivating Her-2/neu--a protein that makes cancer cells grow especially quickly-- produced by a gene found in 25 to 30 percent of all breast tumors. Herceptin caused some patients' cancers to disappear completely; in others, it slowed the progression of the disease and gave the women months or years they wouldn't otherwise have had. Herceptin is the first treatment targeted at a gene defect that gives rise to cancer. It marks the beginning of a new era of treatment for all kinds of cancers. Robert Bazell presents a riveting account of how Herceptin was born. Her-2 is a story of dramatic discoveries and strong personalities, showing the combination of scientific investigation, money, politics, ego, corporate decisions, patient activism, and luck involved in moving this groundbreaking drug from the lab to a patient's bedside. Bazell's deft portraits introduce us to the remarkable people instrumental in Herceptin's history, including Dr. Dennis Slamon, the driven UCLA oncologist who played the primary role in developing the treatment; Lily Tartikoff, wife of television executive Brandon Tartikoff, who tapped into Hollywood money and glamour to help fund Slamon's research; and Marti Nelson, who inspired the activists who lobbied for a "compassionate use" program that would allow women outside the clinical trials to have access to the limited supplies of Herceptin prior to FDA approval of the drug. And throughout there are the stories of the heroic women with advanced breast cancer who volunteered for the trials, risking what time they had left on an unproven treatment. Meticulously researched, written with clarity and compassion, Her-2 is masterly reporting on cutting-edge science.




A Breast Cancer Alphabet


Book Description

A definitive and approachable guide to life during, and after, breast cancer The biggest risk factor for breast cancer is simply being a woman. Madhulika Sikka's A Breast Cancer Alphabet offers a new way to live with and plan past the hardest diagnosis that most women will ever receive: a personal, practical, and deeply informative look at the road from diagnosis to treatment and beyond. What Madhulika Sikka didn't foresee when initially diagnosed, and what this book brings to life so vividly, are the unexpected and minute challenges that make navigating the world of breast cancer all the trickier. A Breast Cancer Alphabet is an inspired reaction to what started as a personal predicament. This A-Z guide to living with breast cancer goes where so many fear to tread: sex (S is for Sex - really?), sentimentality (J is for Journey - it's a cliché we need to dispense with), hair (H is for Hair - yes, you can make a federal case of it) and work (Q is for Quitting - there'll be days when you feel like it). She draws an easy-to-follow, and quite memorable, map of her travels from breast cancer neophyte to seasoned veteran. As a prominent news executive, Madhulika had access to the most cutting edge data on the disease's reach and impact. At the same time, she craved the community of frank talk and personal insight that we rely on in life's toughest moments. This wonderfully inventive book navigates the world of science and story, bringing readers into Madhulika's mind and experience in a way that demystifies breast cancer and offers new hope for those living with it.




The Breast Cancer Wars


Book Description

In this riveting narrative, Barron H. Lerner offers a superb medical and cultural history of our century-long battle with breast cancer. Revisiting the past, Lerner argues, can illuminate and clarify the dilemmas confronted by women with--and at risk for--the disease. Writing with insight and compassion, Lerner tells a compelling story of influential surgeons, anxious patients and committed activists. There are colorful portraits of the leading figures, ranging from the acerbic Dr. William Halsted, who pioneered the disfiguring radical mastectomy at the turn of the century to George Crile, Jr., the Cleveland surgeon who shocked the medical establishment by "going public" with his doubts about mastectomy, to Rose Kushner, a brash journalist who relentlessly educated American women about breast cancer. Lerner offers a fascinating account of the breast cancer wars: the insistent efforts of physicians to vanquish the "enemy"; the fights waged by feminists and maverick doctors to combat a paternalistic legacy that discouraged decision-making by patients; and the struggles of statisticians and researchers to generate definitive data in the face of the great risks and uncertainties raised by the disease. As easy as it is to demonize male physicians, the persistence of the radical mastectomy and other invasive treatments has had as much to do with the complicated scientific understandings of breast cancer as with sexism. In Lerner's hands, the fight against breast cancer opens a window on American medical practice over the last century: the pursuit of dramatic cures with sophisticated technologies, the emergence of patients' rights, the ethical and legal challenges raised by informed consent, and the limited ability of scientific knowledge to provide quick solutions for serious illnesses. A searching and profound work on an emotionally charged issue, The Breast Cancer Wars tells a story that remains of vital importance to modern breast cancer patients, their families and the clinicians who strive to treat and prevent this dreaded disease.