Immuno-oncology


Book Description

Over the last decade, immuno-oncology has witnessed an astonishing pace of discovery and innovation translating into unprecedented successes in the clinical setting, arguably representing one of the most profound and transforming revolution in the history of cancer therapy. This book provides a concise and accurate outline of the main developments in major tumor types including melanoma, lung, breast, brain and renal cell cancers. In addition, transversal chapters that describe the commonalities of some of the therapeutic strategies are provided to cover topics like immune checkpoint biology, T cell engineering or rational combination therapies. Each chapter has been authored by senior key opinion leaders in their respective fields to provide the most up-to-date view on cancer immuno-oncology. To reflect on the key translational aspect of immuno-oncology, all chapters are making explicit connections between basic science discoveries and the resulting translational therapeutic strategies. Immuno-Oncology will be an invaluable source of information for scientists interested in the translation of basic immunology into the clinical practice, as well as for clinician interested in deepening their knowledge of current and upcoming immune strategies in the fight against cancers.




Civil War and Agrarian Unrest


Book Description

The first book that compares the Confederate South and Southern Italy in two contemporaneous civil wars during 1861-1865.




A Nation Within a Nation


Book Description

John Ernest offers a comprehensive survey of the broad-ranging and influential African American organizations and networks formed in the North in the late eighteenth century through the end of the Civil War. He examines fraternal organizations, churches, conventions, mutual aid benefit and literary societies, educational organizations, newspapers, and magazines. Ernest argues these organizations demonstrate how African Americans self-definition was not solely determined by slavery as they tried to create organizations in the hope of creating a community.




Nature and the Environment


Book Description

This volume in the Critical Insights series addresses the themes of nature and the environment in literature. Essays survey the critical conversation regarding these themes, explore the cultural and historical contexts, and offer comparative readings of key texts in the genre. Readers seeking a deeper understanding of the themes can explore them in depth through a variety of critical approaches.




Public Health 101: Improving Community Health


Book Description

From clean drinking water, to seat belts, to immunizations, the impact of public health on every individual is undeniable. For undergraduates, an understanding of the foundations of public health is an essential step toward becoming an educated citizen. Public Health 101 provides a big-picture, population perspective on the determinants of health and disease and the tools available to protect and promote health. It examines the full range of options for intervention including use of the healthcare system, the public health system, and society-wide systems such as laws and taxation.




ALA Bulletin


Book Description




Apollo 17


Book Description

The Apollo 17 flight and lunar landing, the sixth and final lunar landing and third extended science capability mission in the Apollo Program, are discussed with emphasis on the scientific endeavors conducted on the lunar surface. The scientific investigation of the mission is presented in three interrelated types of activities: the lunar surface sampling and observation, the lunar surface experiments, and the inflight experiments. Collection, documentation, and description of the lunar samples are discussed with a preliminary evaluation and analysis. The lunar surface experiments are described, including the results and their relationship to the scientific objectives of each experiment. The geochemical, photographic, geophysical, topographic, and medical data resulting from experiments conducted in flight are presented.







Apollo 12 Preliminary Science Report


Book Description

The Apollo 11 Mission, primarily designed to land men on the Moon and return them safely to Earth, signaled a new phase of the manned space program. Based on the success of Apollo 11, the first of a series of missions designed for the systematic exploration of the Moon was successfully accomplished on Apollo 12. The fact that the Apollo 12 astronauts were able to achieve a pinpoint landing at a preselected site, and then spend an extended time on the lunar surface, graphically illustrates the rapid progress of the Apollo program. The Apollo 12 mission added significantly to man's knowledge of the Moon. The precise landing capability allowed the crew to accomplish a wide variety of preplanned tasks and paved the way for planning future missions to smaller, more selected landing areas with the possibility of significant scientific returns. The publication includes chapters on mission description, summary of scientific results, photographic summary of the Apollo 12 Mission, crew observations, passive seismic experiment, lunar surface magnetometer experiment, the solar-wind spectrometer experiment, suprathermal ion detector experiment (lunar ionosphere detector), cold cathode gage (lunar atmosphere detector), the solar-wind composition experiment, Apollo 12 multispectral photography experiment, preliminary geologic investigation of the Apollo 12 landing site, lunar surface closeup stereoscopic photography, preliminary examination of lunar samples, and preliminary results from Surveyor 3 analysis.