Handbook of Liver Disease


Book Description

Here's instant access to the symptoms, signs, differential diagnosis, and treatment for the full range of liver disorders. Written by an international 'who's who' of hepatology-and now in full color-this new 2nd Edition provides readers with top-notch, authoritative guidance they can count on! Discusses the hottest topics in the field, such as non-alcoholic steatohepatitis (NASH) and the latest information on liver transplantation. Includes expanded coverage of chronic hepatitis C, most notably the use of combination therapy with peginterferon and ribavirin and improvements in the management of the side effects of antiviral therapy. Offers the most recent therapeutic options for the management of chronic hepatitis B and advances in the understanding of the molecular biology of this virus. Updates the approach to the diagnosis of many liver diseases due to newer tests based on molecular techniques and advances in imaging. Features over 340 full-color illustrations. Uses a redesigned templated, outline format that makes reference a snap. Presents a concise, in-depth clinical summary-in an outline format-of the current practice of hepatology for each major disease entity. Provides a liberal use of tables, algorithms, and figures, rendering complex concepts understandable. Includes key point boxes at the beginning of each chapter, providing at-a-glance access to vital information. Includes alert symbols that highlight information that's critical to patient safety.




Drug-Induced Liver Injury


Book Description

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series




Hepatic Critical Care


Book Description

This book focuses on the critical care of the patient with acute, acute on chronic and chronic liver failure as well as the peri-operative care of the patient with liver transplantation. Each of these disease processes is unique in pathophysiological manifestations, underpinnings of physiology and treatment options. Patients with acute, chronic or acute on chronic liver failure are a growing fraction of ICU admissions. Hepatic Critical Care serves as the essential reference for both practicing intensivists at community hospitals and tertiary referral centers. This textbook is also targeted towards trainees specifically interested in taking care of patients with liver disease and liver transplantation.




Acute Liver Failure, An Issue of Clinics in Liver Disease


Book Description

Dr. Pyrsopoulos has assembled the top authors in the field to provide current reviews on acute liver failure, to be the first time this topic is addressed in one volume. Topics are devoted to Classification and Epidemiologic Aspects of Acute Liver Failure; Acute Liver Failure: Mechanisms of disease and multi-systemic involvement; The Pathology of Acute Liver Failure; Liver Regeneration in the Acute Liver Failure Patient; Viral Hepatitis and Acute Liver Failure: Still a Problem; Drug- induced Liver Injury and Acute Liver Failure; Acetaminophen and Acute Liver Failure; Non-Viral Or Drug-Induced Etiologies of Acute Liver Failure; The Clinical Spectrum and Manifestations of Acute Liver Failure; Non ICU Management of Acute Liver Failure; Management of Acute Liver Failure in the ICU Setting; Prognostic Models of Acute Liver Failure; The Role of Liver Transplantation in Acute Liver Failure; and Future Approaches and Therapeutic Modalities for Acute Liver Failure. Readers will come away with a current point of view about how to approach and manage the patient with acute liver failure.




Liver Disease in Children


Book Description

Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.




Transplantation of the Liver


Book Description

Drs. Busuttil and Klintmalm present Transplantation of the Liver, 3rd Edition, which has been thoroughly revised to offer you the latest protocols, surgical approaches, and techniques used in this challenging procedure. Encompassing today's expert knowledge in the field, this medical reference book is an ideal single source for authoritative, up-to-date guidance on every imaginable aspect of liver transplantation. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Access valuable pearls, pitfalls, and insights from Dr. Ronald Busuttil and Dr. Goran Klintmalm, two of the world's preeminent experts in liver surgery. Understand today's full range of transplantation techniques with complete step-by-step descriptions of each, and access the background information and management options for each hepatic disease entity. Take advantage of detailed discussions of everything from pathophysiology and patient and donor selection, to transplantation anesthesia and operative procedures; immunosuppression; postoperative care; and ethical issues. Overcome your toughest challenges in liver transplantation. Many new and thoroughly revised chapters include: Deceased Organ Donation after Cardiac and Brain Death; Liver Transplantation for Non-Alcoholic Steatohepatitis; Extended Criteria Donors; Best Techniques for Biliary and Vascular Reconstruction in Living Donor Transplantation; Small for Size Syndrome; Dual Grafts for Transplantation; Arterial Reconstructions-Pitfalls; Transition of Pediatric Patients to Adulthood; Immunosuppressive Biologic Agents; Long Term Toxicity of Immunosuppressive Therapy; Stem Cell and Liver Regeneration; and Extracorporeal Perfusion for Resuscitation of Marginal Grafts. Stay current in your field and optimize patient outcomes with coverage of the most recent advances in living donor transplantation, pediatric transplantation, and gene and stem cell therapy. Access the latest information on anti-rejection/immunosuppressive drugs, as well as comprehensive discussions of each drug or combination of drugs used to suppress immune system. Effortlessly search the entire text online at Expert Consult.




Acute-on-Chronic Liver Failure, An Issue of Clinics in Liver Disease, E-Book


Book Description

In this issue of Clinics in Liver Disease, guest editor Dr. Nikolaos T. Pyrsopoulos brings his considerable expertise to the topic of Acute-on-Chronic Liver Failure. Recent studies indicate that as many as one in four patients with cirrhosis develop acute-on-chronic liver failure (ACLF) and 25% die within one month. This issue, the first devoted to this topic, provides thorough coverage of critical clinical interventions, including diagnosis, treatment, and management. It also focuses on early recognition of ACLF, which is important for the initiation of aggressive management and ultimately, saving lives. - Contains 17 practice-oriented topics including ACLF: mechanisms of disease and multisystemic involvement; the clinical spectrum and manifestations of ACLF; management of ACLF; maximizing the donor potential for patients with ACLF Listed for Liver Transplant; future approaches and therapeutic modalities for ACLF; and more. - Provides in-depth clinical reviews of acute-on-chronic liver failure, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.




Chronic Liver Failure


Book Description

Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.




Liver Failure


Book Description

This book offers a comprehensive overview of liver failure including Epidemiology, mechanism of the disease, and its clinical manifestations. The diagnosis of numerous types of liver disease leading to liver failure; with specific emphasis on the current and future treatment modalities including up-to-date and extensive information on liver transplantation. It provides the most up-to-date information on liver failure for clinicians, practitioners including GPs, scientists/researchers, postgraduates and allied health professionals. It features an overview of the relevant classification and epidemiologic aspects of acute liver failure along with a thorough review of the mechanisms associated with acute liver failure and multisystemic involvement. Detailed guidance is also provided on the latest treatment techniques including those available for liver transplantation and potential future approaches, enabling the reader to develop a detailed understanding of the topic. Liver Failure: Acute and Acute on Chronic provides a practically applicable guide to the epidemiology and management of liver failure. It features contributions from an outstanding panel of experts in hepatology, gastroenterology and surgery making it a vital up-to-date reference for trainee and practicing medical professionals in a variety of disciplines who encounter these patients.




Diseases of the Abdomen and Pelvis 2018-2021


Book Description

This open access book deals with imaging of the abdomen and pelvis, an area that has seen considerable advances over the past several years, driven by clinical as well as technological developments. The respective chapters, written by internationally respected experts in their fields, focus on imaging diagnosis and interventional therapies in abdominal and pelvic disease; they cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As such, the book offers a comprehensive review of the state of the art in imaging of the abdomen and pelvis. It will be of interest to general radiologists, radiology residents, interventional radiologists, and clinicians from other specialties who want to update their knowledge in this area.