Nuclear Architecture and Dynamics


Book Description

Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines. - Highlights the link between the (bio)chemistry and the (bio)physics of chromatin - Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin - Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds




Advances in Nuclear Architecture


Book Description

This book provides a snapshot of the state-of-the art in the study of mammalian cell nuclear architecture, and features a diverse range of chapters written by top researchers. A key aspect is an emphasis on precise and repeatable quantitative analysis and simulation in addition to the more familiar biological perspective. The fusion of such material frames the future of the discipline. Quantitative contributions stress reproducible and robust 3D analysis, using a variety of tools ranging from point pattern analysis to shape registration methods. Biological insights include the role of nuclear subdomains in cancer, nuclear molecular motors, and a holistic view of gene transcription.




Fundamentals in Nuclear Physics


Book Description

Covers all the phenomenological and experimental data on nuclear physics and demonstrates the latest experimental developments that can be obtained. Introduces modern theories of fundamental processes, in particular the electroweak standard model, without using the sophisticated underlying quantum field theoretical tools. Incorporates all major present applications of nuclear physics at a level that is both understandable by a majority of physicists and scientists of many other fields, and usefull as a first introduction for students who intend to pursue in the domain.




Structural Materials for Generation IV Nuclear Reactors


Book Description

Operating at a high level of fuel efficiency, safety, proliferation-resistance, sustainability and cost, generation IV nuclear reactors promise enhanced features to an energy resource which is already seen as an outstanding source of reliable base load power. The performance and reliability of materials when subjected to the higher neutron doses and extremely corrosive higher temperature environments that will be found in generation IV nuclear reactors are essential areas of study, as key considerations for the successful development of generation IV reactors are suitable structural materials for both in-core and out-of-core applications. Structural Materials for Generation IV Nuclear Reactors explores the current state-of-the art in these areas. Part One reviews the materials, requirements and challenges in generation IV systems. Part Two presents the core materials with chapters on irradiation resistant austenitic steels, ODS/FM steels and refractory metals amongst others. Part Three looks at out-of-core materials. Structural Materials for Generation IV Nuclear Reactors is an essential reference text for professional scientists, engineers and postgraduate researchers involved in the development of generation IV nuclear reactors. - Introduces the higher neutron doses and extremely corrosive higher temperature environments that will be found in generation IV nuclear reactors and implications for structural materials - Contains chapters on the key core and out-of-core materials, from steels to advanced micro-laminates - Written by an expert in that particular area




Nuclear Physics


Book Description

The principal goals of the study were to articulate the scientific rationale and objectives of the field and then to take a long-term strategic view of U.S. nuclear science in the global context for setting future directions for the field. Nuclear Physics: Exploring the Heart of Matter provides a long-term assessment of an outlook for nuclear physics. The first phase of the report articulates the scientific rationale and objectives of the field, while the second phase provides a global context for the field and its long-term priorities and proposes a framework for progress through 2020 and beyond. In the second phase of the study, also developing a framework for progress through 2020 and beyond, the committee carefully considered the balance between universities and government facilities in terms of research and workforce development and the role of international collaborations in leveraging future investments. Nuclear physics today is a diverse field, encompassing research that spans dimensions from a tiny fraction of the volume of the individual particles (neutrons and protons) in the atomic nucleus to the enormous scales of astrophysical objects in the cosmos. Nuclear Physics: Exploring the Heart of Matter explains the research objectives, which include the desire not only to better understand the nature of matter interacting at the nuclear level, but also to describe the state of the universe that existed at the big bang. This report explains how the universe can now be studied in the most advanced colliding-beam accelerators, where strong forces are the dominant interactions, as well as the nature of neutrinos.




An Advanced Course in Modern Nuclear Physics


Book Description

The ?eld of nuclear physics is entering the 21st century in an interesting and exciting way. On the one hand, it is changing qualitatively since new experim- tal developments allow us to direct radioactive and other exotic probes to target nuclei as well as to sparko? extremely energetic nuclear collisions. In parallel, detector systems are of an impressive sophistication. It is di?cult to envisage all the discoveries that will be made in the near future. On the other hand, the app- cations of nuclear science and technology are broadening the limits in medicine, industry, art, archaeology, and the environmental sciences, etc. This implies that the public perception of our ?eld is changing, smoothly but drastically, in c- trast to former times where nuclear weapons and nuclear power plants were the dominant applications perceived by citizens. Both aspects, scienti?c dynamism and popular recognition, should lead the ?eld to an unexpected revival. One of the consequences of the former could be that many brilliant students consider nuclear physics as an excellent ?eld in which to acquire professional expertise. Therefore, one of the challenges of the international nuclear physics community is to try to make the ?eld attractive. That means simply being pedagogic and enthusiastic. Thus, as organisers of an already established summer school, our contribution was to put an emphasis in this session on pedagogy and enthusiasm.







Nuclear Physics


Book Description

Dramatic progress has been made in all branches of physics since the National Research Council's 1986 decadal survey of the field. The Physics in a New Era series explores these advances and looks ahead to future goals. The series includes assessments of the major subfields and reports on several smaller subfields, and preparation has begun on an overview volume on the unity of physics, its relationships to other fields, and its contributions to national needs. Nuclear Physics is the latest volume of the series. The book describes current activity in understanding nuclear structure and symmetries, the behavior of matter at extreme densities, the role of nuclear physics in astrophysics and cosmology, and the instrumentation and facilities used by the field. It makes recommendations on the resources needed for experimental and theoretical advances in the coming decade.




Nuclear Organization and Function


Book Description

This volume is based on presentations by the world-renowned investigators who gathered at the 75th annual Cold Spring Harbor Symposium on Quantitative Biology to discuss the organization and function of the cell nucleus. It reviews the latest advances in research into nuclear structure, the organization of the genome within the nucleus, and spatiotemporal coordination of nuclear processes. The topics examined include nuclear domains, chromatin organization, transcription and RNA processing, DNA replication, nuclear reprogramming, and epigenetics. Cancer, premature aging syndromes, and other diseases that may be associated with altered nuclear organization are also covered.




International Symposium on Nuclear Structure Physics


Book Description

Nuclear structure physics is undergoing a major revival, full of activities and excitement. On the experimental side, this is being made possible by advances in detector technology and accelerator capabilities that give access to data and nuclei (especially exotic nuclei far from stability) never before accessible. On the theoretical side, new concepts, ideas and computational techniques are advancing our understanding of effective interactions, nucleonic correlations, and symmetries of structure.This volume covers a broad range of topics on nuclear structure, including collective excitations, proton-neutron excitation modes, phase transitions, signatures of structure, isospin, structure at both high and low angular momenta, recent developments in nuclear theory, the vast new realm of exotic nuclei far from the valley of stability, and the latest technological advances of detectors and facilities which will lead this branch of physics into the future.