Advances in Therapeutics and Diagnostics of Human Diseases


Book Description

This reference book equips readers with cutting-edge information on the many advances in diagnostic and therapeutic treatments for human diseases that have been made in recent years, with examples from laboratory medicine. Diagnostic procedures and treatment protocols are a critical part of the health care system, providing dynamic information that influences provider decisions with respect to disease prevention, diagnosis, treatment procedures, and management of the disease. With advances in medical technologies over the past few decades, diagnostics have become even more essential to the practice of medicine for personalised diagnosis and treatment. Developments in health care technologies have extended the survival prospects of persons all over the globe. Once serious conditions have become considerably easier to manage and even cure in numerous cases. Constant laboratory investigations in the health sciences have expanded the quality of treatment, life-expectancy, as well as the quality of life for patients. In this book, readers will find a detailed discussion of new methodologies in treating diseases, including 3D technology, and prediction of chronic diseases using computation techniques, which provide promising avenues for the diagnosis, treatment, and prophylaxis of diseases.




Therapeutic Advances in Human Health and Diseases


Book Description

"The book has imperative and up-to-date information on the basics to advanced therapeutic approaches against various life-threatening diseases including vector and parasite-borne diseases, COVID-19, Mucormycosis, and cancer as well. The book harbors extensive knowledge about the applications and effective utilization of advanced personalized medicines, target-based nanoencapsulated phytochemicals, and herbal nanomedicines against life-threatening diseases including cancer, thereby having implications in the cancer biology field encompassing pharmaceutical and life science sectors considerably. Moreover, the proposed book would provide a strong platform for delineating the complex mechanism underlying the disease therapeutics along with the potential therapies countering the existing menace of drug resistance, especially concerning cancer. More so the book will showcase the recent advances in the use of nanocomposite films and molecular-mediated drug delivery for therapeutic applications. The uniqueness of this book is to provide all the possible information from basics to advanced nano-therapeutics at a single platform making it a valuable informative source to the graduates of various universities across the globe to understand multifaceted therapeutic applications against life-threatening diseases. The book is an outstanding compilation comprising comprehensive information on therapeutic advances at a single platform. The book is apt to the present needs and well aligned with the offered curricula in Universities across the globe for UG, PG, and Ph.D. programs encompassing life sciences, medical, paramedical, and pharmaceutical courses. The diversity of chapters in the book are going to covers various aspects of the parasites, pathophysiology, and pathogenesis along with the pivotal role of nanotechnology in drug discovery and nano-biosensors for the detection of coronavirus as well. Moreover, the book has interesting elements of futuristic personalized medicines in combating coronavirus along with remedial therapeutic measures against coronavirus-induced mucormycosis. Another chapter deals with multifaceted therapeutic advances in life-threatening human diseases from traditional, complementary, and integrative medicine to nano-based targeted drug delivery. In the end, the authors have shed light on understanding oncogenesis and cancer and finding an amicable therapeutic nanomedicine solution paving the way towards individualized medicine therapeutics against cancer. With the advent of newer technologies such as combinatorial chemistry high-throughput screening, next generation sequencing, it is now possible to consider that nanotherapeutics and personalized medicines could be the sound death knell for a variety of dreadful diseases including cancer and also to deal with the growing menace of drug-resistance. Once again, our sincere thanks to all the contributing authors who worked like a team to let us complete this book. Special thanks to the Editorial team of the publishing house who were available all the time to impart their valuable input and assistance. Words of appreciation also go to the whole Production Team as well"--




Advances in Cell and Molecular Diagnostics


Book Description

Advances in Cell and Molecular Diagnostics brings the scientific advances in the translation and validation of cellular and molecular discoveries in medicine into the clinical diagnostic setting. It enumerates the description and application of technological advances in the field of cellular and molecular diagnostic medicine, providing an overview of specialized fields, such as biomarker, genetic marker, screening, DNA-profiling, NGS, cytogenetics, transcriptome, cancer biomarkers, prostate specific antigen, and biomarker toxicologies. In addition, it presents novel discoveries and clinical pathologic correlations, including studies in oncology, infectious diseases, inherited diseases, predisposition to disease, and the description or polymorphisms linked to disease states. This book is a valuable resource for oncologists, practitioners and several members of the biomedical field who are interested in understanding how to apply cutting-edge technologies into diagnostics and healthcare. Encompasses the current scientific advances in the translation and validation of cellular and molecular discoveries into the clinical diagnostic setting Explains the application of cellular and molecular diagnostics methodologies in clinical trials Focuses on translating preclinical tests to the bedside in order to help readers apply the most recent technologies to healthcare




Molecular Pathology


Book Description

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase




Rare Diseases


Book Description

A rare disease is any disease or condition that affects a small percentage of the population. Many rare conditions are life-threatening or chronically debilitating, and unfortunately do not have appropriate treatments, rendering them incurable. In recent years, there has been substantial development in the area of rare disease research and its clinical applications, for instance, rare disease biology and genomics, epidemiology and preventions, early detection and screening, and diagnosis and treatment. In this context, this book consolidates the recent advances in rare disease biology and therapeutics, covering a wide spectrum of interrelated topics, and disseminates this essential knowledge in a comprehensible way to a greater scientific and clinical audience as well as patients, caregivers, and drug and device manufacturers, especially to support rare disease product development. Chapters cover such diseases as Felty’s syndrome, Löfgren’s syndrome, mesothelioma, epidermolysis bullosa, and more. This book is a valuable resource not only for medical and allied health students but also for researchers, clinical and nurse geneticists, genetic counselors, and physician assistants.




Global Infectious Disease Surveillance and Detection


Book Description

Early detection is essential to the control of emerging, reemerging, and novel infectious diseases, whether naturally occurring or intentionally introduced. Containing the spread of such diseases in a profoundly interconnected world requires active vigilance for signs of an outbreak, rapid recognition of its presence, and diagnosis of its microbial cause, in addition to strategies and resources for an appropriate and efficient response. Although these actions are often viewed in terms of human public health, they also challenge the plant and animal health communities. Surveillance, defined as "the continual scrutiny of all aspects of occurrence and spread of a disease that are pertinent to effective control", involves the "systematic collection, analysis, interpretation, and dissemination of health data." Disease detection and diagnosis is the act of discovering a novel, emerging, or reemerging disease or disease event and identifying its cause. Diagnosis is "the cornerstone of effective disease control and prevention efforts, including surveillance." Disease surveillance and detection relies heavily on the astute individual: the clinician, veterinarian, plant pathologist, farmer, livestock manager, or agricultural extension agent who notices something unusual, atypical, or suspicious and brings this discovery in a timely way to the attention of an appropriate representative of human public health, veterinary medicine, or agriculture. Most developed countries have the ability to detect and diagnose human, animal, and plant diseases. Global Infectious Disease Surveillance and Detection: Assessing the Challenges-Finding Solutions, Workshop Summary is part of a 10 book series and summarizes the recommendations and presentations of the workshop.




Mass Spectrometry-Based Approaches for Treating Human Diseases and Diagnostics


Book Description

This book presents the technological advances in the field of mass spectrometry-based approaches for treating human diseases and diagnostics as well as the application of such approaches to study, in depth, human diseases, biomarkers discovery and validation, and to provide mechanistic insights of potential new therapeutics. This is an ideal book for students, technicians, researchers, and medical doctors that work in the field of mass spectrometry and proteomics




Advances in Medicine and Medical Research


Book Description

This book focuses on issues in clinical practice and research that are of general interest. The articles primarily focus on understanding the pathogenic mechanisms of diseases, their prevention, and therapy. The topics addressed include cardiovascular regulation with regard to blood pressure and heart rate variability, and to coupling blood pressure changes with subarachnoid fluid oscillations. In addition, the book discusses recent advances in the diagnostics of and targeted molecular therapy for renal and pancreatic malignancies, growth disorders, vitamin D and calcium homeostasis in children in the context of neonatal urolithiasis, and neurosurgical interventions in multifarious age-related diseases of the vertebrae. Neuropsychological aspects of patients' quality of life and of shaping medical staff's attitude toward patients are also addressed. The respective articles are intended to build a bridge between basic and clinical research. Further, the book enhances the current body of knowledge on diagnostics and patient treatment and offers valuable new perspectives on practical clinical issues. As such, it offers a unique resource for clinicians, family physicians, medical scholars, and professionals engaged in patient management.




Recent Advancements in the Diagnosis of Human Disease


Book Description

"This edition highlights the latest development in the diagnosis of various human disease. So far, significant advancement has been made in the development of rapid and sensitive diagnostic techniques. It has aided in the improvement in the diagnosis of various disease, and its control and prevention. The emergence of novel technologies that involves multi-disciplinary approach in the field of biomedical sciences, has improved vastly improved diagnostic methods, having remarkably higher resolution for rapid and precise identification of microbial pathogens. Nonetheless, there is a persistent need to have additional sensitive diagnostic methods that can be used in rapid detection and identification of disease causing emerging infectious microbes"--




Disease Control Priorities, Third Edition (Volume 6)


Book Description

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.