Advances in X-Linked Mental Retardation Research and Treatment: 2013 Edition


Book Description

Advances in X-Linked Mental Retardation Research and Treatment: 2013 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about ZZZAdditional Research in a compact format. The editors have built Advances in X-Linked Mental Retardation Research and Treatment: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in X-Linked Mental Retardation Research and Treatment: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.




Atlas of X-Linked Intellectual Disability Syndromes


Book Description

The Atlas of Intellectual Disability Syndromes presents a concise description of 150 clinically distinctive syndromes caused by genes on the X chromosome. Each entry includes photographs and a differential matrix of similar syndromes. Appendices identify syndromes with common features and provide the location or mapping limits and function of responsible genes.




Mental Disorders and Disabilities Among Low-Income Children


Book Description

Children living in poverty are more likely to have mental health problems, and their conditions are more likely to be severe. Of the approximately 1.3 million children who were recipients of Supplemental Security Income (SSI) disability benefits in 2013, about 50% were disabled primarily due to a mental disorder. An increase in the number of children who are recipients of SSI benefits due to mental disorders has been observed through several decades of the program beginning in 1985 and continuing through 2010. Nevertheless, less than 1% of children in the United States are recipients of SSI disability benefits for a mental disorder. At the request of the Social Security Administration, Mental Disorders and Disability Among Low-Income Children compares national trends in the number of children with mental disorders with the trends in the number of children receiving benefits from the SSI program, and describes the possible factors that may contribute to any differences between the two groups. This report provides an overview of the current status of the diagnosis and treatment of mental disorders, and the levels of impairment in the U.S. population under age 18. The report focuses on 6 mental disorders, chosen due to their prevalence and the severity of disability attributed to those disorders within the SSI disability program: attention-deficit/hyperactivity disorder, oppositional defiant disorder/conduct disorder, autism spectrum disorder, intellectual disability, learning disabilities, and mood disorders. While this report is not a comprehensive discussion of these disorders, Mental Disorders and Disability Among Low-Income Children provides the best currently available information regarding demographics, diagnosis, treatment, and expectations for the disorder time course - both the natural course and under treatment.




Advancements of Mass Spectrometry in Biomedical Research


Book Description

This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease, and psychiatry. Additional chapters focus on methodology, technologies and instrumentation, as well as on analysis of protein-protein interactions, protein quantitation, and protein post-translational modifications. Various omics fields such as proteomics, metabolomics, glycomics, lipidomics, and adductomics are also covered. Applications of mass spectrometry in biotechnological and pharmaceutical industry are also discussed. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research, but also to initiate and improve their own work. This book acts as a technical guide as well as a conceptual guide to the newest information in this exciting field.







Autism Spectrum Disorders: Developmental Trajectories, Neurobiological Basis, Treatment Update


Book Description

This Research Topic has the aim to fill the gap of the many unresolved scientific issues on Autism Spectrum Disorders (ASD) that are still in need of investigation, Targeted treatments based on the understanding of the underlying pathogenic mechanisms of disease are still lacking. Further research is awaited and should be obtained through a significant effort on experimental treatment trials and neuroscience research. This Topic is divided in two main sections, one covering clinical issues and another on basic neurosciences of Autism Spectrum Disorders. A more detailed description of the contents of the articles is provided in the editorial at the beginning of the issue.




Treatment of Neurodevelopmental Disorders


Book Description

This cutting-edge book brings advances in genetics, neurobiology, and psychopharmacology to the clinic to enhance treatment for neurodevelopmental disorders. Significant progress has been made in identifying the neurobiological mechanisms of several disorders and targeted treatments are modifying the outcome of these disorders. However, the ability to utilize this knowledge has not been summarized in one place for the practicing clinician. This book will fill that gap by providing the theoretical underpinnings and the latest advances in targeted treatments. Several neurodevelopmental disorders are reviewed in detail including clinical features and behavioral phenotypes, standard treatments and new targeted treatments based on the latest advances in neurobiology and the animal model studies that have led to new treatments. The disorders covered include psychiatric disorders: schizophrenia, depression, autism and ADHD; single gene disorders including Tuberous Sclerosis, Fragile X Syndrome and fragile X- associated disorders, Angelman Syndrome, PKU, and Muscular Dystrophies; and complex genetic disorders such as Down syndrome. This book also highlights the commonalities across disorders and new genetic and molecular concepts in an easy to read format. This is a very exciting time for new targeted treatments and this volume is a landmark treatise on this new age of treatment.







Advanced Practice Psychiatric Nursing, Second Edition


Book Description

This text reinvigorates the emphasis on the therapeutic relationship that is the core of nursing practice. It also relies on our strong history as therapists and introduces a need for integration of all aspects of care, a true holistic approach that characterizes the nursing perspective...The book should serve as a review for nurses who are studying for certification exams [and is] very useful for coursework in DNP programs as well as the masters programs in psychiatric mental health nursing. -Grayce M. Sills, PhD, RN, FAAN Professor Emerita, Ohio State University From the Foreword Now in its second edition, this groundbreaking text and reference continues to be the only resource for APRNs to focus on integrative interventions forindividuals with mental health problems across the lifespan. Combining theory and practice, it provides a clear framework for integratingpsychopharmacology, psychotherapy, and Complementary and Alternative Medicine (CAM) into advanced practice nursing. The second edition is thoroughlyupdated to reflect current research, new classifications in DSM 5, genetic testing, and increased use of telemental health delivery. It builds upon itslifespan focus and updates quick-access pediatric pointers and aging alerts. Additionally, the resource incorporates the 2014 publication of the ANA Scopeand Standards of Practice for Psychiatric Nurses, offers a new focus on QSEN requirements, and responds to the need to reduce health disparities andaddress cultural considerations. Organized around psychiatric syndromes, the text covers neurobiology, theory and research evidence related to psychopharmacology, psychotherapy, and CAMinterventions. It provides a virtual buffet of clear treatment options in the form of well-designed decision trees and accompanying explanatory narratives.The text also includes a section on such special considerations as substance misuse, medical problems, pregnancy, and forensic issues that often co-occurwith psychiatric syndromes. Concise, clear language and abundant charts, graphs, and algorithms enhance the books’ value in supporting sound clinicalreasoning. New to the Second Edition: Thoroughly updated, evidence-based content Encompasses new research Presents three completely new chapters on Integrative Management of Impulse Control, Telehealth, and Quality Improvement and Evidence-BasedPractice Includes the expertise of new contributors Reflects DSM 5 updates, ANA Standard of Practice for Psychiatric Nurses, and QSEN standards Updates quick-access Pediatric Pointers and Aging Alerts Key Features: Integrates theory and practice Simplifies complex concepts using clear language while retaining depth of information Supports clinical decision-making skills through easy-to-follow Decision Trees Organized around psychiatric syndromes Edited by internationally acclaimed practitioner/educators




Cancer Genomics


Book Description

Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment. - Tools such as sidebars, key concept summaries, a glossary, and acronym and abbreviation definitions make this book highly accessible to researchers from several fields associated with cancer genomics. - Contributions from thought leaders provide valuable historical perspective to relate the advances in the field to current technologies and literature.