Advancing Research on Understanding Environmental Effects of UV Filters from Sunscreens


Book Description

Sunscreens and a variety of other products contain chemical ultraviolet (UV) filters that absorb or block the sun's radiation and thereby help mitigate harms to human skin from the sun. The 2022 NASEM report Review of Fate, Exposure, and Effects of Sunscreens in Aquatic Environments and Implications for Sunscreen Usage and Human Health called on the EPA to conduct an ecological risk assessment of UV filters to characterize the possible risks to aquatic ecosystems and the species that live in them. However, the 2022 report also identified a number of knowledge gaps and research barriers that may limit understanding of those ecological risks. To share progress and identify opportunities to further address gaps and barriers, NASEM hosted a workshop in Washington, D.C., on January 23?24, 2023, entitled Workshop to Advance Research on Understanding Environmental Effects of UV Filters in Sunscreens. Through a series of prepared talks, panel discussions, and structured breakout discussions, participants examined the 2022 report and its management context; explored data needs and analytical challenges relevant to the development of accurate toxicity metrics for UV filters; and suggested opportunities to improve and standardize toxicity testing for these chemicals. These proceedings has been prepared by the workshop rapporteur as a factual summary of what occurred at the workshop.




Challenges in Sun Protection


Book Description

In the early 20th century, tanned skin was associated with good health. However, people began to protect themselves against potential overexposure to avoid sunburns. Around 1945, the first sunscreen products became available. In the years to follow, a vast number of different sunscreen filters and frameworks regulating filter substances and preparations, and methods characterizing sunscreen products were developed. The perception regarding the tasks of sunscreen products changed several times – initially it was promoted as a lifestyle product, then as a skin cancer preventive means, and more recently also for anti-aging. Different purposes and the widespread use of these products have led to myriad studies and a wealth of information. In this volume, the editors present a current collection of information analyzing and discussing issues related to sunscreen products and their use. These include challenges regarding the ideal sunscreen product including filter selection and formulation issues, measurement methods, performance characterization, safety, and regulatory issues. Further papers address topics related to the use of sunscreen products in everyday life, in vulnerable cohorts and outdoor workers. Controversial topics such as environmental effects of sunscreen products and the risks and benefits of UV radiation in the context of skin cancer, vitamin D and cardiovascular and metabolic health are also covered.




Cosmeceuticals


Book Description

Cosmeceuticals are ingredients or products that provide cosmetic and therapeutic benefits and which can be obtained without a prescription. They are one of the fastest growing segments in the personal care product market. Even in the worst economic climate, sales of cosmetics remain robust. Beauty enhancers are our best means of feel-good escapism, and we are not about to give them up. The ingredients, sales locations, and the regulation of sales are dynamic aspects of the industry. Here we give you a heads-up on where the market is going so you can make strategic decisions for your practice. This book will give you an understanding of facial cosmeceuticals examining the needs of the face, moisturizer formulation, noninvasive testing, and clinical evaluation to establish efficacy. It sheds light on topics such as the delivery mechanisms of active ingredients, vitamin A and C and other antioxidants, growth factors and stem cells, peptides, or amino acids. Topics also include the use of cosmeceuticals for the treatment of acne, rosacea, and hair loss and for hair care as well as the treatment of scars and cosmeceuticals for sun protection and protection from pollution. It also covers aspects of nutraceuticals and diets for healthy skin.




Analysis of Cosmetic Products


Book Description

Analysis of Cosmetic Products, Second Edition advises the reader from an analytical chemistry perspective on the choice of suitable analytical methods for production monitoring and quality control of cosmetic products. This book helps professionals working in the cosmetic industry or in research laboratories select appropriate analytical procedures for production, maintain in-market quality control of cosmetic products and plan for the appropriate types of biomedical and environmental testing. This updated and expanded second edition covers fundamental concepts relating to cosmetic products, current global legislation, the latest analytical methods for monitoring and quality control, characterization of nanomaterials and other new active ingredients, and an introduction to green cosmetic chemistry. - Provides comprehensive coverage of the specific analytical procedures for different analytes and cosmetic samples - Includes information on the biomonitoring of cosmetic ingredients in the human body and the environment - Describes the most recent developments in global legislation governing the cosmetics industry - Introduces green technologies and the use of nanomaterials in the development and analysis of cosmetic ingredients




Review of Fate, Exposure, and Effects of Sunscreens in Aquatic Environments and Implications for Sunscreen Usage and Human Health


Book Description

Regular use of sunscreens has been shown to reduce the risk of sunburn and skin cancer, and slow photoaging of skin. Sunscreens can rinse off into water where people are swimming or wading, and can also enter bodies of water through wastewater such as from bathing or showering. As a result, the ultraviolet (UV) filters - the active ingredients in sunscreens that reduce the amount of UV radiation on skin - have been detected in the water, sediment, and animal tissues in aquatic environments. Because the impact of these filters on aquatic ecosystems is not fully understood, assessment is needed to better understand their environmental impacts. This report calls on the U.S. Environmental Protection Agency to conduct an ecological risk assessment of UV filters to characterize the possible risks to aquatic ecosystems and the species that live in them. EPA should focus on environments more likely to be exposed such as those with heavy recreational use, or where wastewater and urban runoff enter the water. The risk assessment should cover a broad range of species and biological effects and could consider potential interacting effects among UV filters and with other environmental stresses such as climate change. In addition, the report describes the role of sunscreens in preventing skin cancer and what is known about how human health could be affected by potential changes in usage. While the need for a risk assessment is urgent, research is needed to advance understanding of both risks to the environment from UV filters and impacts to human health from changing sunscreen availability and usage.




Sunscreens in Coastal Ecosystems


Book Description

This book provides a comprehensive and authoritative review of the chemical analysis of UV filters in coastal waters and their impact on the marine environment. The sun care is today the most important sector within the cosmetics industry, with annual increases in sales. The main components of sunscreens, organic and inorganic UV filters, have been detected in many coastal regions, with the highest concentrations in coastal areas under high anthropogenic pressure. Moreover, these compounds have been found to be bioaccumulated in aquatic biota causing biological and toxicological responses; some organic UV filters act as endocrine disruptors in aquatic biota, affecting survival, behavior, growth, development and reproduction. On the other hand, inorganic UV filters, mainly based on nanoparticles, have been demonstrated to have various impacts on marine organisms, such as inducing oxidative stress in abalones, accumulating in microalgae, affecting the immune response in mussels, bleaching corals, and genotoxicity in fish, among others. All these effects of sunscreens on the marine environment highlight the need for more stringent and environmentally friendly regulations. This book covers the latest analytical methodologies used in assessing the impact of UV filters impact on marine waters, especially on marine biota, and also critiques the global regulation of UV filters and the environmental risk of using sunscreens. Featuring specific case studies of the environmental effects of sunscreens in the Mediterranean Sea and Hawaii, which highlight the importance of balancing human health with environmental health of coastal ecosystems, it will appeal not only to scientists and students from various disciplines (environmental chemistry, biology, ecology, biogeochemistry, fisheries and climate change among others), but also to environmental managers wanting to promote new restrictive regulations on the use of UV filters, and to professionals from the cosmetic industry interested in the development of eco-friendly sunscreens.




Personal Care Products in the Aquatic Environment


Book Description

This volume offers an overview of the occurrence and distribution of personal care products in continental and marine waters, presents analytical methods and degradation technologies and discusses their impact on human health. Experts from different disciplines highlight major issues for each family of compounds related to their occurrence in the water column as well as in solid and biota samples, methodological strategies for their analysis, non-conventional degradation technologies, (eco)toxicity data and their human and environmental risk assessment. The book also includes a general introduction to personal care products, covering their properties, use, behaviour and regulatory framework, and a final chapter identifying knowledge gaps and future research trends. It will appeal to experts from various fields of research, including analytical and environmental chemistry, toxicology and environmental engineering.







Bioindicators & Biomonitors


Book Description

Table of contents




pH of the Skin: Issues and Challenges


Book Description

The concept of expressing acidity as the negative logarithm of the hydrogen ion concentration was defined and termed pH in the beginning of the 20th century. The general usefulness of the pH concept for life science was recognized and later gained importance to analytical research. Reports on results of pH measurements from living skin established the term acid mantle - the skin's own protective shield that maintains a naturally acid pH. It is invisible to the eye but crucial to the overall wellbeing of skin. Chronic alkalization can throw this acid mantle out of balance, leading to inflammation, dermatitis, and atopic skin diseases. It is therefore no surprise, that skin pH shifts have been observed in various skin pathologies. It is also obvious that the pH in topically applied preparations may play an important role. Optimal pH and buffer capacity within topical preparations not only support stability of active ingredients and auxiliary materials, but may also increase absorption of the non-ionized species of an acidic or a basic active ingredient. They may even open up opportunities to modify and "correct" skin pH and hence accelerate barrier recovery and maintain or enhance barrier integrity. Further efforts are needed to standardize and improve pH measurements in biological media or pharmaceutical/cosmetic vehicles to increase and ensure quality, comparability, and relevance of research data. In this volume, we present a unique collection of papers that address past, present and future issues of the pH of healthy and diseased skin. It is hoped that this collection will foster future efforts in clinical and experimental skin research.