AEDS Monitor


Book Description




The Monitor


Book Description




Gliomas


Book Description

Researchers' knowledge of gliomas continues to advance rapidly at both the basic and translational levels, and Gliomas provides a thorough overview of the evolving fields of tumor biology and clinical medicine as they relate to our understanding of brain tumors. Gliomas reviews the current paradigms that underlie these fields, beginning with the molecular epidemiology of glioma susceptibility and prognosis through population-based science and genome-wide association studies. The book's discussion of imaging modalities extends beyond advances in anatomical imaging to include metabolic and physiological studies. This work provides thorough discussion of the clinical view of tumors, ranging from the presentation of the patient to surgical management, and covers all therapeutic options for patient care, including chemotherapy, targeted molecular therapies, immunotherapies, and even personalized approaches to impact the set of lesions. Additionally, the book discusses radiotherapy with regard to the many options available to treat patients using myriad fractionated techniques with various sources. Finally, Gliomas reviews issues specific to the quality of life for patients, and techniques for maximizing the effect of caregivers. Edited and authored by premier researchers from around the world, Gliomas is a comprehensive reference for clinicians and researchers seeking the most up-to-date information on gliomas, and a guide to the best ways to effectively manage glioma patients and their care. - Synthesizes widely dispersed information on the management of gliomas into one comprehensive resource - Chapters written by international authors who are preeminent researchers in the field - Fully explores the therapeutic options for patient care, from chemotherapy to radiotherapy to personalized approaches




Antiepileptic Drugs


Book Description

The thoroughly revised, updated Fifth Edition of this classic is the m ost comprehensive, current, and authoritative reference on all anticon vulsants available today. This edition features detailed profiles of n ewer drugs--including levetiracetam, oxcarbazepine, tiagabine, topiram ate, and zonisamide--and new chapters on use of antiepileptic drugs in children and during pregnancy. Drugs are covered in alphabetical ord er and in an easy-to-follow format: mechanisms of action; chemistry, b iotransformation, and pharmacokinetics; interactions; clinical efficac y and use; and adverse effects. Coverage of clinical use includes none pileptic and psychiatric disorders where appropriate. This edition has been trimmed to manageable size by shortening chapters on older, less frequently used drugs.




Methods of Therapeutic Drug Monitoring Including Pharmacogenetics


Book Description

Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot technology and microextraction methods. In addition, the book includes new drugs, such as tyrosine kinase inhibitors and the monitoring of immunosuppressant drugs. - Presents a unique, interdisciplinary approach that appeals to a wide range of users - Written by authors from international labs, providing a global perspective that can be applied in various regulatory environments - Features additional therapeutic drugs to reflect the rising number of immunocompromised patients - Includes a new mass spectroscopic methods chapter to capture the frequent use in TDM and the improved availability of LC-MS across laboratories




Therapeutic Drug Monitoring


Book Description

Therapeutic Drug Monitoring: Newer Drugs and Biomarkers features timely topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This reference also discusses the limitations of current commercially available immunoassays for therapeutic monitoring. It presents new and sophisticated techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs. Written by leading international experts and geared toward clinical pathologists, toxicologists, clinical chemists, laboratory professionals and physicians, this book is an essential resource on the current practice of therapeutic drug monitoring in improving patient safety. - Includes both the technical and clinical issues associated with therapeutic drug monitoring - Discusses the utility of therapeutic drug monitoring of newer drugs such as antiretroviral agents, anticonvulsants, antidepressants etc. - Provides up-to-date information on issues in pharmacogenomics and personalized medicine with emphasis on therapy with warfarin, certain anticancer drugs and antidepressants - Covers important content on the limitations of commercially available immunoassays (chemical tests) for therapeutic drug monitoring and additional analytical techniques




Therapeutic Drug Monitoring Data


Book Description

Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs for advanced cancer treatment, and thoroughly updated chapters that address new pitfalls and problems in the lab. - Serves as a ready resource of information for commonly monitored drugs - Presents a useful, quick guide for those making decisions related to monitoring and interpretation of results - Provides concise, easily digestible content for clinical laboratory scientists, toxicologists and clinicians




Optimizing Health Monitoring Systems With Wireless Technology


Book Description

The digital transformation of healthcare delivery is in full swing. Health monitoring is increasingly becoming more effective, efficient, and timely through mobile devices that are now widely available. This, as well as wireless technology, is essential to assessing, diagnosing, and treating medical ailments. However, systems and applications that boost wellness must be properly designed and regulated in order to protect the patient and provide the best care. Optimizing Health Monitoring Systems With Wireless Technology is an essential publication that focuses on critical issues related to the design, development, and deployment of wireless technology solutions for healthcare and wellness. Highlighting a broad range of topics including solution evaluation, privacy and security, and policy and regulation, this book is ideally designed for clinicians, hospital directors, hospital managers, consultants, health IT developers, healthcare providers, engineers, software developers, policymakers, researchers, academicians, and students.




Clinical Challenges in Therapeutic Drug Monitoring


Book Description

Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations. - Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoring - Focuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoring - Explores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interference - Explains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window




Antiepileptic Drugs


Book Description

This book reviews the use of antiepileptic drugs focusing on the interactions between these drugs and between antiepileptics and other drugs. These interactions can be beneficial or can cause harm. The aim of this book is to increase awareness of the possible impact of combination pharmacotherapies. Pharmacokinetic and pharmacodynamic interactions are discussed supported by clinical and experimental data. The book consists of five sections covering the general concepts and advantages of combination therapies, the principles of drug interactions, the mechanisms of interactions, drug interactions in specific populations or in patients with co-morbid health conditions, and concludes with a look at the future directions for this field of research. The book will be of interest to all who prescribe antiepileptics to epileptic and non-epileptic patients, including epileptologists, neurologists, neuro-pediatricians, psychiatrists and general practitioners.