Aggregation Functions


Book Description

A rigorous and self-contained exposition of aggregation functions and their properties.




Aggregation of Therapeutic Proteins


Book Description

This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has been mostly experimental. The knowledge in this book can greatly help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area. This book fills such a need by providing an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins.




Matter Aggregation


Book Description

Within the human-machine collaborations cultivated in the digital age, crafts and materials are playing an increasingly important role in forming various ways of matter aggregation for architecture. Based on the pedagogical exploration of the design studio--Matter Aggregation at UVA, the book seeks new values of wood craft for contemporary architectural design, by introducing digital design and robotic fabrication techniques into the design process for timber building. The book integrates explorations of traditional crafts with digital fabrication technique, establishing a digital crafting as a new field for contemporary practice. The book explores the computational mechanisms and diagrammatic grammar within these craft-based aggregation systems, paying close attention to geometrical configurations, material effects and fabrication details and take advantage of these qualities to produce a unique spatiality.




Aggregation Functions in Theory and in Practise


Book Description

This volume collects the extended abstracts of 45 contributions of participants to the Seventh International Summer School on Aggregation Operators (AGOP 2013), held at Pamplona in July, 16-20, 2013. These contributions cover a very broad range, from the purely theoretical ones to those with a more applied focus. Moreover, the summaries of the plenary talks and tutorials given at the same workshop are included. Together they provide a good overview of recent trends in research in aggregation functions which can be of interest to both researchers in Physics or Mathematics working on the theoretical basis of aggregation functions, and to engineers who require them for applications.




Practical MongoDB


Book Description

The "one-size-fits-all" thinking regarding traditional RDBMSs has been challenged in the last few years by the emergence of diversified NoSQL databases. More than 120 NoSQL databases are now available in the market, and the market leader by far is MongoDB. With so many companies opting for MongoDB as their NoSQL database of choice, there's a need for a practical how-to combined with expert advice for getting the most out of the software. Beginning with a short introduction to the basics of NoSQL databases, MongoDB experts Navin Sabharwal and Shankatala Gupta Edward introduce readers to MongoDB – the leading document based NoSQL database, acquainting them step by step with all aspects of MongoDB. They cover the data model, underlying architecture, how to code using Mongo Shell, and administration of the MongoDB platform, among other topics. The book also provides clear guidelines and practical examples for architecting and developing applications using the MongoDB platform and deploying them. Database developers, architects, and database administrators will find useful information covering all aspects of the MongoDB platform and how to put it to use practically. Practical Guide to MongoDB provides readers with: A solid understanding of NoSQL databases An understanding of how to get started with MongoDB Methodical coverage of the architecture, development, and administration of MongoDB A plethora of "How to’s" enabling you to use the technology most efficiently to solve the problems you face Practical MongoDB is for those just starting to learning to work with NoSQL databases in general and MongoDB in particular. Skills in these areas are in demand, making this book essential reading for those who want to work more productively or break into big data work. It will prove equally useful for entrepreneurs and others who like to work with new technologies.




Aggregation Operators


Book Description

1. The increasing number of research papers appeared in the last years that either make use of aggregation functions or contribute to its theoretieal study asses its growing importance in the field of Fuzzy Logie and in others where uncertainty and imprecision play a relevant role. Since these papers are pub lished in many journals, few books and several proceedings of conferences, books on aggregation are partieularly welcome. To my knowledge, "Agrega tion Operators. New Trends and Applications" is the first book aiming at generality , and I take it as a honour to write this Foreword in response to the gentle demand of its editors, Radko Mesiar, Tomasa Calvo and Gaspar Mayor. My pleasure also derives from the fact that twenty years aga I was one of the first Spaniards interested in the study of aggregation functions, and this book includes work by several Spanish authors. The book contains nice and relevant original papers, authored by some of the most outstanding researchers in the field, and since it can serve, as the editors point out in the Preface, as a small handbook on aggregation, the book is very useful for those entering the subject for the first time. The book also contains apart dealing with potential areas of application, so it can be helpful in gaining insight on the future developments.




Amyloid Fibrils and Prefibrillar Aggregates


Book Description

Summing up almost a decade of biomedical research, this topical and eagerly awaited handbook is the first reference on the topic to incorporate recent breakthroughs in amyloid research. The first part covers the structural biology of amyloid fibrils and pre-fibrillar assemblies, including a description of current models for amyloid formation. The second part looks at the diagnosis and biomedical study of amyloid in humans and in animal models, while the final section discusses pharmacological approaches to manipulating amyloid and also looks at its physiological roles in lower and higher organisms. For Biochemists, Molecular Biologists, Neurobiologists, Neurophysiologists and those working in the Pharmaceutical Industry.




Reef Fish Spawning Aggregations: Biology, Research and Management


Book Description

Reef fish spawning aggregations, ranging from small groups to many tens of thousands of individuals, are spectacular but poorly known natural phenomena whereby fish assemble at specific times and locations to spawn. For some species these large groups may be the only form of reproduction, the high fish numbers briefly giving a false impression of stability and abundance—an ‘illusion of plenty’. They are often a focus for intensive seasonal fishing because of their predictability and because many important commercial fishes form them. Highly vulnerable to overexploitation, many aggregations and their associated fisheries, have disappeared or are in decline. Few are effectively managed or incorporated into protected areas. Aggregations are not well understood by fishery scientists, managers and conservationists and their significance little appreciated by fishers or the wider public. To ensure their persistence to replenish important fisheries in coral ecosystems, maintain their ecosystem function and continue to delight divers, a significant change in perspective is needed to foster protection and management. This book provides comprehensive and practical coverage of the biology, study and management of reef fish aggregations, exploring their how, when, where, and why. It explores ways to better protect, study, manage and conserve them, while identifying key data gaps and questions. The text is extensively illustrated with many unique, never before published, photographs and graphics. Case studies on over 20 interesting and important fishes are included, outlining their biology and fisheries and highlighting major concerns and challenges.




Analysis of Aggregates and Particles in Protein Pharmaceuticals


Book Description

This book describes how to address the analysis of aggregates and particles in protein pharmaceuticals, provides a comprehensive overview of current methods and integrated approaches used to quantify and characterize aggregates and particles, and discusses regulatory requirements. Analytical methods covered in the book include separation, light scattering, microscopy, and spectroscopy.




Social Anthropology and Human Origins


Book Description

The study of human origins is one of the most fascinating branches of anthropology. Yet it has rarely been considered by social or cultural anthropologists, who represent the largest subfield of the discipline. In this powerful study Alan Barnard aims to bridge this gap. Barnard argues that social anthropological theory has much to contribute to our understanding of human evolution, including changes in technology, subsistence and exchange, family and kinship, as well as to the study of language, art, ritual and belief. This book places social anthropology in the context of a widely-conceived constellation of anthropological sciences. It incorporates recent findings in many fields, including primate studies, archaeology, linguistics and human genetics. In clear, accessible style Barnard addresses the fundamental questions surrounding the evolution of human society and the prehistory of culture, suggesting a new direction for social anthropology that will open up debate across the discipline as a whole.