Algebraic and Discrete Mathematical Methods for Modern Biology


Book Description

Written by experts in both mathematics and biology, Algebraic and Discrete Mathematical Methods for Modern Biology offers a bridge between math and biology, providing a framework for simulating, analyzing, predicting, and modulating the behavior of complex biological systems. Each chapter begins with a question from modern biology, followed by the description of certain mathematical methods and theory appropriate in the search of answers. Every topic provides a fast-track pathway through the problem by presenting the biological foundation, covering the relevant mathematical theory, and highlighting connections between them. Many of the projects and exercises embedded in each chapter utilize specialized software, providing students with much-needed familiarity and experience with computing applications, critical components of the "modern biology" skill set. This book is appropriate for mathematics courses such as finite mathematics, discrete structures, linear algebra, abstract/modern algebra, graph theory, probability, bioinformatics, statistics, biostatistics, and modeling, as well as for biology courses such as genetics, cell and molecular biology, biochemistry, ecology, and evolution. - Examines significant questions in modern biology and their mathematical treatments - Presents important mathematical concepts and tools in the context of essential biology - Features material of interest to students in both mathematics and biology - Presents chapters in modular format so coverage need not follow the Table of Contents - Introduces projects appropriate for undergraduate research - Utilizes freely accessible software for visualization, simulation, and analysis in modern biology - Requires no calculus as a prerequisite - Provides a complete Solutions Manual - Features a companion website with supplementary resources




Algebraic Statistics for Computational Biology


Book Description

This book, first published in 2005, offers an introduction to the application of algebraic statistics to computational biology.




Algebraic Biology


Book Description

"This volume constitutes the refereed proceedings of the Second International Conference on Algebraic Biology, held at the Castle of Hagenberg, Austria in July 2007. The conference was run as part of the Research Institute for Symbolic Computation (RISC) Summer 2007. Nineteen full papers are presented, together with three invited papers and four tutorials. Each paper has been carefully reviewed by the book's team of expert editors to ensure each one meets the highest standards of research and scholarship. The conference served as an interdisciplinary forum for the presentation of research on all aspects of the application of symbolic computation in biology, including computer algebra, computational logic, and related methods. Papers also examine solutions to problems in biology using symbolic methods."--Publisher's website.




Algebraic and Combinatorial Computational Biology


Book Description

Algebraic and Combinatorial Computational Biology introduces students and researchers to a panorama of powerful and current methods for mathematical problem-solving in modern computational biology. Presented in a modular format, each topic introduces the biological foundations of the field, covers specialized mathematical theory, and concludes by highlighting connections with ongoing research, particularly open questions. The work addresses problems from gene regulation, neuroscience, phylogenetics, molecular networks, assembly and folding of biomolecular structures, and the use of clustering methods in biology. A number of these chapters are surveys of new topics that have not been previously compiled into one unified source. These topics were selected because they highlight the use of technique from algebra and combinatorics that are becoming mainstream in the life sciences. - Integrates a comprehensive selection of tools from computational biology into educational or research programs - Emphasizes practical problem-solving through multiple exercises, projects and spinoff computational simulations - Contains scalable material for use in undergraduate and graduate-level classes and research projects - Introduces the reader to freely-available professional software - Supported by illustrative datasets and adaptable computer code




Algebraic Biology


Book Description

This book constitutes the refereed proceedings of the Third International Conference on Algebraic Biology, AB 2008, held at the Castle of Hagenberg, Austria in July 2008 as part of the RISC Summer 2008, organized by the Research Institute for Symbolic Computation. The 14 revised full papers presented together with 3 tutorial lectures were carefully reviewed and selected from 27 submissions. The conference is the interdisciplinary forum for the presentation of research on all aspects of applications of symbolic computation (computer algebra, computational logic, and related methods) to various issues in biology and life sciences as well as other problems in biology being approached with symbolic methods.




An Introduction to the Mathematics of Biology: with Computer Algebra Models


Book Description

Biology is a source of fascination for most scientists, whether their training is in the life sciences or not. In particular, there is a special satisfaction in discovering an understanding of biology in the context of another science like mathematics. Fortunately there are plenty of interesting (and fun) problems in biology, and virtually all scientific disciplines have become the richer for it. For example, two major journals, Mathematical Biosciences and Journal of Mathematical Biology, have tripled in size since their inceptions 20-25 years ago. The various sciences have a great deal to give to one another, but there are still too many fences separating them. In writing this book we have adopted the philosophy that mathematical biology is not merely the intrusion of one science into another, but has a unity of its own, in which both the biology and the math ematics should be equal and complete, and should flow smoothly into and out of one another. We have taught mathematical biology with this philosophy in mind and have seen profound changes in the outlooks of our science and engineering students: The attitude of "Oh no, another pendulum on a spring problem!," or "Yet one more LCD circuit!" completely disappeared in the face of applications of mathematics in biology. There is a timeliness in calculating a protocol for ad ministering a drug.




Algebraic Biology, Matrix Genetics, And Genetic Intelligence


Book Description

Historically, mathematics, probability, and statistics have been widely used in the biological sciences. Recent progress in genomics has yielded many millions of gene sequences. But what do these sequences tell us and what are the generalities and rules governed by them? It seems that we understand very little about the genetic contexts required to 'read' them. There is more to life than the genomic blueprint of each organism. Life functions within the natural laws that we know and the ones we do not know. The development of modern mathematical natural sciences is based on the use of certain mathematical tools. Mathematics can be used to understand life from the molecular to the biosphere level.This book provides the foundation and latest advances for an emerging research area that uses tools from symbolic computation, computer algebra and logic, algebraic geometry, fractal geometry, probability and statistics, and matrix algebra to formalize and solve biological problems and explore its applications in algebraic biology and code biology. It introduces highly interdisciplinary topics in biomathematics such as matrix genetics, gestalt biology, bio-antenna arrays, resonance genetics, quantum biology, and more.




Algebraic and Numeric Biology


Book Description

This book constitutes the refereed proceedings of the 4th International Conference on Algebraic Biology, ANB 2010, held at the Castle of Hagenberg, Austria in July/August 2010. The conference is a follow up of the AB Conference. The 10 papers were carefully reviewed and selected from numerous submissions. The papers are organized in topical sections on mathematical modeling, system analysis and design, genomics, molecular structure analysis, automata theory, artificial intelligence, sequence analysis, automated reasoning, formal language and hybrid symbolic numerical methods.




Applications of Automata Theory and Algebra


Book Description

This book was originally written in 1969 by Berkeley mathematician John Rhodes. It is the founding work in what is now called algebraic engineering, an emerging field created by using the unifying scheme of finite state machine models and their complexity to tie together many fields: finite group theory, semigroup theory, automata and sequential machine theory, finite phase space physics, metabolic and evolutionary biology, epistemology, mathematical theory of psychoanalysis, philosophy, and game theory. The author thus introduced a completely original algebraic approach to complexity and the understanding of finite systems. The unpublished manuscript, often referred to as "The Wild Book," became an underground classic, continually requested in manuscript form, and read by many leading researchers in mathematics, complex systems, artificial intelligence, and systems biology. Yet it has never been available in print until now. This first published edition has been edited and updated by Chrystopher Nehaniv for the 21st century. Its novel and rigorous development of the mathematical theory of complexity via algebraic automata theory reveals deep and unexpected connections between algebra (semigroups) and areas of science and engineering. Co-founded by John Rhodes and Kenneth Krohn in 1962, algebraic automata theory has grown into a vibrant area of research, including the complexity of automata, and semigroups and machines from an algebraic viewpoint, and which also touches on infinite groups, and other areas of algebra. This book sets the stage for the application of algebraic automata theory to areas outside mathematics. The material and references have been brought up to date bythe editor as much as possible, yet the book retains its distinct character and the bold yet rigorous style of the author. Included are treatments of topics such as models of time as algebra via semigroup theory; evolution-complexity relations applicable to both ontogeny and evolution; an approach to classification of biological reactions and pathways; the relationships among coordinate systems, symmetry, and conservation principles in physics; discussion of "punctuated equilibrium" (prior to Stephen Jay Gould); games; and applications to psychology, psychoanalysis, epistemology, and the purpose of life. The approach and contents will be of interest to a variety of researchers and students in algebra as well as to the diverse, growing areas of applications of algebra in science and engineering. Moreover, many parts of the book will be intelligible to non-mathematicians, including students and experts from diverse backgrounds.




Advances in Artificial Systems for Logistics Engineering


Book Description

The book comprises high-quality refereed research papers presented at the Second International Conference on Artificial Intelligence and Logistics Engineering (ICAILE2022), held in Kyiv, Ukraine, on February 20–22, 2022, organized jointly by the National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute," Wuhan University of Technology, Nanning University, National Aviation University, and the International Research Association of Modern Education and Computer Science. The topics discussed in the book include state-of-the-art papers in artificial intelligence and logistics engineering. It is an excellent source of references for researchers, graduate students, engineers, management practitioners, and undergraduate students interested in artificial intelligence and its applications in logistics engineering.