Author : Ajit Varki
Publisher : CSHL Press
Page : 694 pages
File Size : 39,60 MB
Release : 1999
Category : Medical
ISBN : 9780879696818
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author : Ajit Varki
Publisher :
Page : 680 pages
File Size : 49,76 MB
Release : 1999
Category : Medical
ISBN :
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author : Sen-itiroh Hakomori
Publisher :
Page : 362 pages
File Size : 49,4 MB
Release : 1988
Category : Medical
ISBN :
Author :
Publisher : Academic Press
Page : 418 pages
File Size : 21,85 MB
Release : 2015-02-26
Category : Science
ISBN : 0128016140
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students
Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
Page : 2004 pages
File Size : 26,28 MB
Release : 2017-03-10
Category : Medical
ISBN : 111900084X
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author : Sen-Itiroh Hakomori
Publisher : John Wiley & Sons
Page : 350 pages
File Size : 28,87 MB
Release : 1988-09-01
Category :
ISBN : 9780471617372
Author : Minoru Fukuda
Publisher : CRC Press
Page : 342 pages
File Size : 16,61 MB
Release : 1991-12-13
Category : Science
ISBN : 9780849364358
Cell Surface Carbohydrates and Cell Development summarizes knowledge on the structure and function of cell surface carbohydrates in development and differentiation. The chapters include reviews on the expression of cell type-specific carbohydrates and their roles in cell-cell interaction. In particular, the role of cell surface carbohydrates in immune cell response, malignant transformation, fertilization, and neural cell development are addressed. This includes the exciting discovery about the role of adhesive molecules in leukocyte-endothellium interaction. Cell Surface Carbohydrates and Cell Development also summarizes the latest knowledge on structure and biosynthesis of carbohydrates, the role of specific carbohydrate modification, and animal lectins. The book will be useful to researchers and students interested in the biology of glycoproteins and biotechnology.
Author : Inka Brockhausen
Publisher : Springer Science & Business Media
Page : 241 pages
File Size : 26,68 MB
Release : 2013-11-21
Category : Science
ISBN : 3662219603
Diverse alterations of glycosylation occur in diseases such as cancer, metastasis, leukemia, inflammatory and other diseases. The glycosylation abnormalities found in disease are the result of complex rearrangements of the oligosaccharide assembly by glycosyltransferases. This volume reviews several mechanisms that may underly the extremely complex alterations in disease. Disease specific glycosylation may contribute to the disease process by altering cellular functions, or may be exploited therapeutically. Specific therapy may be aimed at correcting glycosylation abnormalities based on knowledge of the mechanisms leading to the disease phenotype and the three-dimensional interactions between carbohydrates and carbohydrate-binding molecules.
Author : Katsunori Tanaka
Publisher : John Wiley & Sons
Page : 560 pages
File Size : 43,76 MB
Release : 2020-04-27
Category : Science
ISBN : 3527344322
Provides timely, comprehensive coverage of in vivo chemical reactions within live animals This handbook summarizes the interdisciplinary expertise of both chemists and biologists performing in vivo chemical reactions within live animals. By comparing and contrasting currently available chemical and biological techniques, it serves not just as a collection of the pioneering work done in animal-based studies, but also as a technical guide to help readers decide which tools are suitable and best for their experimental needs. The Handbook of In Vivo Chemistry in Mice: From Lab to Living System introduces readers to general information about live animal experiments and detection methods commonly used for these animal models. It focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release. Topics include: currently available mouse models; biocompatible fluorophores; radionuclides for radiodiagnosis/radiotherapy; live animal imaging techniques such as positron emission tomography (PET) imaging; magnetic resonance imaging (MRI); ultrasound imaging; hybrid imaging; biocompatible chemical reactions; ligand-directed nucleophilic substitution chemistry; biorthogonal prodrug release strategies; and various selective targeting strategies for live animals. -Completely covers current techniques of in vivo chemistry performed in live animals -Describes general information about commonly used live animal experiments and detection methods -Focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release -Places emphasis on material properties required for the development of appropriate compounds to be used for imaging and therapeutic purposes in preclinical applications Handbook of In Vivo Chemistry in Mice: From Lab to Living System will be of great interest to pharmaceutical chemists, life scientists, and organic chemists. It will also appeal to those working in the pharmaceutical and biotechnology industries.
Author : Enrico Mihich
Publisher : Springer Science & Business Media
Page : 351 pages
File Size : 28,88 MB
Release : 2013-06-29
Category : Medical
ISBN : 1489913521
The Ninth Annual Pezcoller Symposium entitled "The Biology of Tumors" was held in Rovereto, Italy, June 4-7, 1997. It focused on the genetic mechanisms underlying het erogeneity of tumor cell populations and tumor cell differentiation, on interactions be tween tumor cells and cells of host defenses, and the mechanisms of angiogenesis. With presentations at the cutting edge of progress and stimulating discussions, this symposium addressed issues related to phenomena concerned with cell regulation and cell interactions as determined by activated genes through the appropriate and timely media tion of gene products. Important methodologies that would allow scientists to measure dif ferentially genes and gene products and thus validate many of the mechanisms of control currently proposed were considered, as were the molecular basis of tumor recognition by the immune system, interactions between cells and molecular mechanisms of cell regula tion as they are affected by or implemented through these interactions. The molecular and cellular mechanisms of tumor vascularization were also discussed. It was recognized that angiogenesis provides a potential site of therapeutic intervention and this makes it even more important to understand the mechanisms underlying it. We wish to thank the participants in the symposium for their substantial contribu tions and their participation in the spirited discussions that followed. We would also like to thank Drs.
