Ammon's Horn, or The Mystery of the Brain


Book Description

Five cutting-edge scientists compete for $100 million and control of a new institute dedicated to eradicating Alzheimer’s in this edifying, Da Vinci Code-esque thriller. Spurred by his wife’s Alzheimer’s diagnosis and disenchanted with the slow progress in finding a cure, a rich Swiss businessman launches a contest for promising young neuroscientists who can think “outside the box.” Chosen for their scientific excellence and originality, they must travel throughout Europe in search of the answers to five fiendishly difficult riddles, each combining an enigmatic neuroscientific question with a geographical and historical challenge. As their personal stories unfold, the competitors share their moments of elation and disappointment when they solve a riddle or reach a dead end. Soon a conspiracy materializes to threaten and endanger the scientists, which at first seems random, but then becomes increasingly deliberate and targeted. The nature of the riddles and the talents of the competitors open a world of discovery for us too as we learn about some of the most pressing areas in current brain research, such as neurodegenerative diseases, stem cell grafts, artificial intelligence, drug addiction, genetics, and the mechanisms of memory. And as the candidates visit some of the great European cities—Prague, Vienna, Cordoba, Cambridge, Geneva, Venice—we also experience their beauty and intrigue.




The Structure of Ammon's Horn


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Neural and Brain Modeling


Book Description

Neural and Brain Modeling reviews models used to study neural interactions. The book also discusses 54 computer programs that simulate the dynamics of neurons and neuronal networks to illustrate between unit and systemic levels of nervous system functions. The models of neural and brain operations are composed of three sections: models of generic mechanisms; models of specific neuronal systems; and models of generic operations, networks, and systems. The text discusses the computational problems related to galvanizing a neuronal population though an activity in the multifiber input system. The investigator can use a computer technique to simulate multiple interacting neuronal populations. For example, he can investigate the case of a single local region that contains two populations of neurons: namely, a parent population of excitatory cells, and a second set of inhibitory neurons. Computer simulation models predict the various dynamic activity occurring in the complicated structure and physiology of neuronal systems. Computer models can be used in "top-down" brain/mind research where the systemic, global, and emergent properties of nervous systems are generated. The book is recommended for behavioral scientists, psychiatrists, psychologists, computer programmers, students, and professors in human behavior.




New Advances on Zika Virus Research


Book Description

Zika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family that historically has been associated with mild febrile illness. However, the recent outbreaks in Brazil in 2015 and its rapid spread throughout South and Central America and the Caribbean, together with its association with severe neurological disorders—including fetal microcephaly and Guillain-Barré syndrome in adults—have changed the historic perspective of ZIKV. Currently, ZIKV is considered an important public health concern that has the potential to affect millions of people worldwide. The significance of ZIKV in human health and the lack of approved vaccines and/or antiviral drugs to combat ZIKV infection have triggered a global effort to develop effective countermeasures to prevent and/or treat ZIKV infection. In this Special Issue of Viruses, we have assembled a collection of 32 research and review articles that cover the more recent advances on ZIKV molecular biology, replication and transmission, virus–host interactions, pathogenesis, epidemiology, vaccine development, antivirals, and viral diagnosis.




An Odyssey Through the Brain, Behavior and the Mind


Book Description

Much of contemporary behavioral or cognitive neuroscience is concerned with discovering the neural basis of psychological processes such as attention, cognition, consciousness, perception, and memory. In sharp divergence from this field, An Odyssey Through the Brain, Behavior and the Mind can be regarded as an elaborate demonstration that the large scale features of brain electrical activity are related to sensory and motor processes in various ways but are not organised in accordance with conventional psychological concepts. It is argued that much of the traditional lore concerning the mind is based on prescientific philosophical assumptions and has little relevance to brain function. The first ten chapters of An Odyssey Through the Brain, Behavior and the Mind give a personal account of how the various discoveries that gave rise to these views came to be made. This is followed by discussions of brain organization in relation to behavior, learning and memory, sleep and consciousness, and the general problem of the mind.




Phantoms in the Brain


Book Description

Neuroscientist V.S. Ramachandran is internationally renowned for uncovering answers to the deep and quirky questions of human nature that few scientists have dared to address. His bold insights about the brain are matched only by the stunning simplicity of his experiments -- using such low-tech tools as cotton swabs, glasses of water and dime-store mirrors. In Phantoms in the Brain, Dr. Ramachandran recounts how his work with patients who have bizarre neurological disorders has shed new light on the deep architecture of the brain, and what these findings tell us about who we are, how we construct our body image, why we laugh or become depressed, why we may believe in God, how we make decisions, deceive ourselves and dream, perhaps even why we're so clever at philosophy, music and art. Some of his most notable cases: A woman paralyzed on the left side of her body who believes she is lifting a tray of drinks with both hands offers a unique opportunity to test Freud's theory of denial. A man who insists he is talking with God challenges us to ask: Could we be "wired" for religious experience? A woman who hallucinates cartoon characters illustrates how, in a sense, we are all hallucinating, all the time. Dr. Ramachandran's inspired medical detective work pushes the boundaries of medicine's last great frontier -- the human mind -- yielding new and provocative insights into the "big questions" about consciousness and the self.







Neuroscience


Book Description

An introduction to the structure and function of the nervous system that emphasizes the history of experiments and observations that led to modern neuroscientific knowledge. This introduction to neuroscience is unique in its emphasis on how we know what we know about the structure and function of the nervous system. What are the observations and experiments that have taught us about the brain and spinal cord? The book traces our current neuroscientific knowledge to many and varied sources, including ancient observations on the role of the spinal cord in posture and movement, nineteenth-century neuroanatomists' descriptions of the nature of nerve cells, physicians' attempts throughout history to correlate the site of a brain injury with its symptoms, and experiments on the brains of invertebrates. After an overview of the brain and its connections to the sensory and motor systems, Neuroscience discusses, among other topics, the structure of nerve cells; electrical transmission in the nervous system; chemical transmission and the mechanism of drug action; sensation; vision; hearing; movement; learning and memory; language and the brain; neurological disease; personality and emotion; the treatment of mental illness; and consciousness. It explains the sometimes baffling Latin names for brain subdivisions; discusses the role of technology in the field, from microscopes to EEGs; and describes the many varieties of scientific discovery. The book's novel perspective offers a particularly effective way for students to learn about neuroscience. It also makes it clear that past contributions offer a valuable guide for thinking about the puzzles that remain.




The Three-pound Enigma


Book Description

Describes the development of the human brain from conception to death, profiles some of the leading researchers working to unlock its secrets, and answers questions about such topics as dreams, consciousness, memory, and emotion.




The Burning House


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