Analysis of Antibiotic/Drug Residues in Food Products of Animal Origin


Book Description

In the last three decades. use of antibiotics/drugs in animal husbandry programs has grown tremendously. Antibiotics/drugs are used therapeutically to cure diseases. and subtherapeutically to control the outbreak of diseases, improve feed efficiency and promote growth. The presence of antibiotic/drug residues in food products of animal origin. i.e •• meat, poultry and milk, can be a potential health hazard to consumers. Significant research is being done to develop new methods or to improve on existing methods to confirm and quantitatively determine the antibiotic/drug residues in meat, poultry and milk. This book covers recent development and application of various analytical techniques for the determination of antibiotic/drug residues in food products of animal origin. I thank the authors for their time and efforts in preparing the manuscripts and "all the reviewers for reviewing the manuscripts. I also thank to the Division of Agricultural and Food Chemistry of the American Chemical Society for sponsoring the symposium and Hewlett Packard, Palo Alto, CA, Perkin Elmer Corp., Norwalk, CT, Millipore Corporation, Milford, MA, and Kraft General Foods, Glenview, IL, for their generous financial support for the symposium. Vipin K. Agarwal New Haven, CT v CONTENTS Importance of Laboratory Validations and Accurate Descriptions of Analytical Procedures for Drug Residues in Foods ................. .




The Use of Drugs in Food Animals


Book Description

The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.




Chemical Analysis of Antibiotic Residues in Food


Book Description

An insightful exploration of the key aspects concerning the chemical analysis of antibiotic residues in food The presence of excess residues from frequent antibiotic use in animals is not only illegal, but can pose serious health risks by contaminating products for human consumption such as meat and milk. Chemical Analysis of Antibiotic Residues in Food is a single-source reference for readers interested in the development of analytical methods for analyzing antibiotic residues in food. It covers themes that include quality assurance and quality control, antibiotic chemical properties, pharmacokinetics, metabolism, distribution, food safety regulations, and chemical analysis. In addition, the material presented includes background information valuable for understanding the choice of marker residue and target animal tissue to use for regulatory analysis. This comprehensive reference: Includes topics on general issues related to screening and confirmatory methods Presents updated information on food safety regulation based on routine screening and confirmatory methods, especially LC-MS Provides general guidance for method development, validation, and estimation of measurement uncertainty Chemical Analysis of Antibiotic Residues in Food is written and organized with a balance between practical use and theory to provide laboratories with a solid and reliable reference on antibiotic residue analysis. Thorough coverage elicits the latest scientific findings to assist the ongoing efforts toward refining analytical methods for producing safe foods of animal origin.







Veterinary Drug Residues


Book Description

The purpose of this second edition is to bring together the current rapid developments and activities in residues of veterinary drugs within the European Community. The EEC legislation is summarised. There is information on the Reference Laboratories, the Maximum Residues Limits (MRL) and the criteria for the methods to be used for routine analysis of residues by Member States and third countries wishing to export meat to the EC. The current state of examination of residues practised and the analytical methods used in Member States is described in detail. There is a section on quality assurance in the laboratory and also supporting information on residues and chemical/physical data of the most important veterinary drugs




The Evolving Threat of Antimicrobial Resistance


Book Description

Antibiotic resistance development is a natural process of adaption leading to a limited lifespan of antibiotics. Unnecessary and inappropriate use of antibiotics favours the emergence and spread of resistant bacteria. A crisis has been building up over decades, so that today common and life-threatening infections are becoming difficult or even impossible to treat. It is time to take much stronger action worldwide to avert an ever increasing health and economic burden. A new WHO publication "The evolving threat of antimicrobial resistance--Options for action" describes examples of policy activities that have addressed AMR in different parts of the world. The aim is to raise awareness and to stimulate further coordinated efforts.




Improving Food Safety Through a One Health Approach


Book Description

Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.




Veterinary Medicine and Pharmaceuticals


Book Description

Veterinary pharmaceuticals provide animals with the requisite, complete animal health care. The availability of safe and good quality medicines in the right amounts is needed in achieving optimum animal health care. The economic benefits of animal food products cannot be under-estimated. Veterinary pharmaceuticals are needed to meet the ever-growing demand of animal protein for the human population. However, their routine and unguarded use play significant roles in many public health issues, such as antimicrobial resistance. The practices, knowledge, and awareness needed on the use and application of veterinary pharmaceuticals amongst farmers, animal health professionals, microbiologists, and policy makers remain key in ensuring a safe and healthy food chain for all. In the field of veterinary medicine, canine practice is a challenge to veterinarians. In recent years, newer diagnostic methods and therapeutic protocols have been published on a regular basis. Along with the existing knowledge of important canine diseases like ascites, duodenal disorders, pericardial effusions, and canine mastitis, this book is supplemented with all the latest information. Discussion of duodenal disorders in dogs, including IBD and SIBO, is an important topic in day-to-day practice. Ascites and mastitis in dogs are also important topics and are discussed in this book. Each topic carries practical points for the diagnosis and management of important diseases of dogs. Hence, this book will be very useful for canine practitioners.




Management of Emerging Public Health Issues and Risks


Book Description

Management of Emerging Public Health Issues and Risks: Multidisciplinary Approaches to the Changing Environment addresses the threats facing the rapidly changing world and provides guidance on how to manage risks to population health. Unlike conventional and recognized risks (major, industrial, and natural), emerging risks are characterized by low or non-existent scientific knowledge, high levels of uncertainty, and different levels of acceptability by the relevant authorities and exposed populations. Emerging risk must be analyzed through multiple and crossed approaches identifying the phenomenon linked to the emergence of risk but also by combining scientific, policy and social data in order to provide more enlightened decision making. Management of Emerging Public Health Issues and Risks: Multidisciplinary Approaches to the Changing Environment provides examples of transdisciplinary approaches used to characterize, analyze, and manage emerging risks. This book will be useful for public health researchers, policy makers, and students as well as those working in emergency management, risk management, security, environmental health, nanomaterials, and food science. - Presents emerging risks from the technological, environmental, health, and energy sectors, as well as their social impacts - Contextualizes emerging risks as new threats, existing threats in new locations, and known issues, which are newly recognized as risks due to increased scientific knowledge - Includes case studies from around the world to reinforce concepts




WHO guidelines on use of medically important antimicrobials in food-producing animals


Book Description

WHO has launched new guidelines on use of medically important antimicrobials in food-producing animals, recommending that farmers and the food industry stop using antibiotics routinely to promote growth and prevent disease in healthy animals. These guidelines aim to help preserve the effectiveness of antibiotics that are important for human medicine by reducing their use in animals.