Aniline and Its Derivatives


Book Description




Aniline and Its Derivatives


Book Description




Pyridines: From Lab to Production


Book Description

Pyridines: From Lab to Production provides a synthetic armory of tools to aid the practicing chemist by reviewing the most reliable historical methods alongside new methods/ Written by scientists who have actually used these in synthesis. By emphasizing tricks and tips to optimize reactions for the best yields and purity, which are often missing from the primary literature, this book provides another dimension for the synthetic chemist. A combined academic and industrial approach evaluates the best methods for different scales of reaction and discusses practical tips (e.g. when to stop a reaction early to maximize purity or when to re-use side products). Chapters also assess whether to make or source starting materials, how to connect them and what are the best synthetic routes. The book is designed to be a stand-alone reference, but also provides cross references to leading reviews and the Comprehensive Heterocyclic Chemistry reference works for those who want to learn more. - Reviews tried and tested practical methods to help the reader select the best method for their research - Includes tips, tricks and hints to enable the reader to get the best yield or cleanest product out of their reaction for synthesising or transforming a pyridine derivative - Written by both academic researchers and industry leaders this provides a unique view of how to get the most out of a reaction no matter what scale you are running this on




Asymmetric Dearomatization Reactions


Book Description

The first comprehensive account of the rapidly growing field of asymmetric dearomatization reactions with a focus on catalytic methods. It introduces the concept of dearomatization and describes recent progress in asymmetric reaction procedures with different catalyst systems, such as organocatalysts, transition metal catalysts, and enzymes. Chapters on dearomatizations of electron-deficient aromatic rings, dearomatization reactions via transition metal-catalyzed cross-couplings as well as dearomatization strategies in the synthesis of complex natural products are also included. Written by pioneers in the field, this is a highly valuable source of information not only for professional synthetic chemists in academia and industry but also for all those are interested in asymmetric methodologies and organic synthesis in general.




Crystal Engineering: The Design and Application of Functional Solids


Book Description

Crystal engineers need an understanding of bonding theory, computational chemistry, applied spectroscopy, structural methods, synthesis strategies, and applications of custom-designed solids. This book contains chapters on all these topics, written by internationally recognized experts, plus contributions from leading researchers in the field.




Aniline and Its Analogs


Book Description

The human life is simple as well as quite intrigued and it always tries to find solutions to unending problems and challenges. We know that the need is the mother of invention and the scientists in the world are saints of modern age, as based on their tireless efforts the humans have made a significant progress in various fields as telecommunications, information technology, space technology, infrastructures, food technology through green revolution, life-saving drugs, etc. All these fields need chemicals, which must be manufactured at commercial scales. However, the old technologies are handicapped with unlimited limitations for commercial production of these much needed chemicals. As an old man needs help to cross the road, such limitations in the commercial productions of these chemicals are overcome with co-operative effects of other additives as promoters of reaction rates, which in turn help produce the desired products in quantitative yields. Isn’t it interesting to find out what kind of these promoters are, as they have been identified and successfully used through a long journey of innovative, cost-effective process developments with excellent yields and purities of the targeted molecules, which find number of applications in human life. New technologies with above attributes are the essence of this book entitled as “Aniline and its Analogs”, which covers the old and new methods and technologies of their preparations and manufacturing till date, which is compiled by a versatile and an accomplished scientist.







Quinazolinone and Quinazoline Derivatives


Book Description

One of the problems with modern public health is target searching for new highly effective medicinal preparations. Among those medicinal preparations are the natural and synthetic origins of quinazolinone-4 derivatives. Quinazolinone derivatives are reported to be physiologically and pharmacologically active. They also exhibit a wide range of activities such as anticonvulsant, antiinflammatory, antifungal, antimalarial, and sedative properties. Some of these compounds are identified as drugs used as diuretics, vasodilators, and antihypertensive agents. Moreover, sulfonamide derivatives have been widely used as bacteriostatic agents. Prompted by the above-mentioned facts and in conjunction with our ongoing program on the utility of readily obtainable starting material for the synthesis of heterocyclic systems of biological interest, we have decided to synthesize a series of quinazolinone derivatives having sulfonamide moiety with a potentially wide spectrum of biological responses.