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New Antiepileptic Drugs

Author : Francesco Pisani

Publisher : Elsevier Publishing Company

Page : 216 pages

File Size : 47,45 MB

Release : 1991

Category : Medical

ISBN :

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Book Description

The pharmacological fight against epilepsy began many centuries ago when Hippocrates discovered that the cause of epilepsy is natural, as opposed to supernatural and, as a consequence, must be treated with a natural remedy. Even though science has significantly progressed since that era, the challenge to find remedies for epilepsy is ever present. The aim of this particular volume is to offer an up-to-date review of the most recent advances in antiepileptic drug development, considered from various viewpoints: (i) general, by taking into account the size of refractory epilepsy and its related problems; (ii) experimental, by exploring the mechanisms of epileptogenesis and the possiblility of influencing it through drugs, and (iii) clinical, by describing the results obtained with compounds currently at an advanced stage of testing.



The Epilepsies

Author : Chrysostomos P. Panayiotopoulos

Publisher : Springer

Page : 570 pages

File Size : 27,25 MB

Release : 2005

Category : Medical

ISBN :

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Book Description

This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.



Drug-Induced Liver Injury

Author :

Publisher : Academic Press

Page : 290 pages

File Size : 25,57 MB

Release : 2019-07-13

Category : Medical

ISBN : 0128173173

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Book Description

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series



Antiepileptic Drugs

Author : Jerzy Majkowski

Publisher : Cambridge University Press

Page : 530 pages

File Size : 14,20 MB

Release : 2005-05-26

Category : Medical

ISBN : 9780521822190

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Book Description

This book reviews the use of antiepileptic drugs focusing on the interactions between these drugs and between antiepileptics and other drugs. These interactions can be beneficial or can cause harm. The aim of this book is to increase awareness of the possible impact of combination pharmacotherapies. Pharmacokinetic and pharmacodynamic interactions are discussed supported by clinical and experimental data. The book consists of five sections covering the general concepts and advantages of combination therapies, the principles of drug interactions, the mechanisms of interactions, drug interactions in specific populations or in patients with co-morbid health conditions, and concludes with a look at the future directions for this field of research. The book will be of interest to all who prescribe antiepileptics to epileptic and non-epileptic patients, including epileptologists, neurologists, neuro-pediatricians, psychiatrists and general practitioners.



Mechanisms of Action of Antiepileptic Drugs

Author : H. Steve White

Publisher : Professional Communications

Page : 168 pages

File Size : 50,39 MB

Release : 2010

Category : Medical

ISBN : 1932610669

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Book Description

Mechanisms of Action of Antiepileptic Drugs provides a review of all of the mechanisms of action (MOA) of each of the classes of antiepileptic drugs. This is a graphic-intensive text, with detailed illustrations of the various MOA. Introductory and concluding chapters discuss the relevance of MOA to clinical practice. A brief review of neurophysiology of normal and epileptic neurons is followed by individual chapters dedicated to the MOA of each class of antiepileptic drug.



The Treatment of Epilepsy

Author : Simon Shorvon

Publisher : John Wiley & Sons

Page : 1072 pages

File Size : 10,55 MB

Release : 2015-09-15

Category : Medical

ISBN : 1118936981

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Book Description

Highly Commended at the British Medical Association Book Awards 2016 The Treatment of Epilepsy, fourth edition, is a comprehensive reference and clinical guide to the pharmacological, medical and surgical options available in the treatment of epilepsy. The text is compiled by a group of internationally renowned editors and contributors and is now in full color and extensively illustrated The first two sections cover the background to, and principles of, treatment in different clinical situations Section three comprises a series of systematic reviews of contemporary drug therapy, devoting one chapter to each anti-epileptic drug and covering all clinically-relevant aspects Section four focuses on the surgical options, devoting individual chapters to each of the modalities of presurgical assessment and to each surgical operation or approach This 4th edition is extensively revised incorporating the many recent developments in therapy, and comprises 81 chapters from world experts from 18 countries



Antiepileptic Drug Interactions

Author : Philip Patsalos

Publisher : Springer Science & Business Media

Page : 464 pages

File Size : 46,93 MB

Release : 2012-12-03

Category : Medical

ISBN : 1447124340

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Book Description

Antiepileptic Drug Interactions: A Clinical Guide, Second Edition provides a pocket-sized, systematic description of the most clinically relevant drug interactions that occur between AEDs and also between AEDs and non-AEDs. AEDs are presented alphabetically and by drug class in three sections for easy access: Drug interactions between AEDs; Drug interactions between AEDs and non-AEDs: Interactions affecting AEDs; and Drug interactions between AEDs and non-AEDs: Interactions affected by AEDs. Antiepileptic Drug Interactions: A Clinical Guide, Second Edition should help physicians make more rational choices when polytherapy regimens are indicated and should be of interest to all who treat patients with epilepsy: neurologists and neurosurgeons, trainees at all levels, general practitioners and epilepsy nurse specialists.



Antiepileptic Drugs

Author : M J Eadie

Publisher :

Page : 676 pages

File Size : 33,80 MB

Release : 1999-04-16

Category :

ISBN : 9783642600739

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Book Description

This volume provides up to date knowledge of the pharmacologies of the various antiepileptic drugs, especially those which have become available since 1984 when the previous edition (Handbook of Experimental Pharmacology, Volume 74: Antiepileptic Drugs, edited by H.-H. Frey and D. Janz) appeared. The data concerning the individual drugs are presented in a structured format. There are also chapters providing overviews of subjects such as the neurophysiological and biochemical mechanisms of action of the antiepileptic drugs, their testing in experimental animals, their interactions, their clinical use, and the new agents currently in the course of development.



Introduction to Epilepsy

Author : Gonzalo Alarcón

Publisher : Cambridge University Press

Page : 641 pages

File Size : 42,9 MB

Release : 2012-04-26

Category : Medical

ISBN : 0521691583

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Book Description

Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.



Antiepileptic Drugs

Author : Ali A. Asadi-Pooya

Publisher : Oxford University Press

Page : 299 pages

File Size : 12,32 MB

Release : 2016

Category : Medical

ISBN : 0190214961

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Book Description

This concise handbook provides up-to-date clinical guidance on effective selection, prescription, and usage of antiepileptic drugs for patients with epilepsy in various medical conditions. This text discusses choosing drugs when faced with various medical comorbidities; how to correctly prescribe, titrate, and taper drugs; how to monitor drug efficacy and side effects; how to diagnose and manage toxicity; and how antiepileptic drugs interact with other medications. This text fills an unmet need as a practical, patient-oriented reference and leads to improved patient care. This is the perfect guide for physicians looking to ensure safe practices in antiepileptic drug therapy.