Antihypertensive Drugs


Book Description

Arterial hypertension is one of the most important preventable contributors to disease and death, and is commonly treated with antihypertensive drugs combined with appropriate changes in life-style. The first chapter focuses on the options in the enantioseparation of antihypertensive drugs, the synthesis of single enantiomers and chiral aspects of their action and dispositions. The second chapter of this book examines the potential genotoxic effects of five Angiotensin II receptor blockers, analysed in vivo and in vitro in human peripheral blood lymphocytes (PBLs). The third chapter includes a general description about polymorphism and some techniques used in polymorphism characterisation. Then, the specific description of some antihypertensive drugs that present polymorphism phenomena are introduced. Finally, hypertension is by far the most important modifiable risk factor for cardiovascular disease in sub-Saharan Africa. In this book, the authors discuss the ethnic/racial peculiarities in the incidence, pathophysiology and management of hypertension in the black hypertensive patient.




Neurocritical Care Pharmacotherapy


Book Description

Neurocritical Care Pharmacotherapy: A Clinican's Guide is a practical, succinct but comprehensive pharmacy handbook provides up-to-date clinical guidance on the effective selection, prescription, and usage of neurocritical care drugs for patients with acute neurologic illnesses. The treatment of the critically ill neurologic patient is often difficult, specialized, and includes drugs infrequently used in other intensive care units such as antiepileptic drugs, osmotic agents or acute immunotherapy such as intravenous immunoglobulin and plasma exchange. This text discusses choosing the right combination of drugs; how to correctly prescribe and administer the drugs; how to monitor drug efficacy and side effects; how neurocritical care drugs interact with other medications; and comprehensive coverage of current treatment options. Key Feature of this Manual Include - A brief discussion of the basic pharmacology of each neurocritical drug, with an emphasis on how to select and use these drugs in multiple clinical contexts. - 150 drugs accompanied by a diagram for quick comprehension and drug administration guides. - Unique blending of expertise of neurointensivist with a critical care pharmacist to provide a vital resource for both specialities - References for further reading that are oriented toward utility in clinical practice.




Hepatotoxicity


Book Description

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.







Evidence-Based Hypertension


Book Description

This is a practice-oriented textbook for primary care clinicians on managing hypertension. The book summarizes all available research evidence that clinicians need to care for hypertensive patients. It also interprets the data to make it meaningful and useful and that advises readers about the quality and quantity of the evidence supporting the findings. Some of the main topics addressed in this book include taking accurate blood pressure measurements, determining the effectiveness of various blood pressure treatments, controlling difficult to control blood pressure, and treating hypertensive patients with other comorbid conditions.




Diabetes and Hypertension


Book Description

Diabetes and hypertension have evolved as two of the modern day epidemics affecting millions of people around the world. These two common co-morbidities lead to substantial increase in cardiovascular disease, the major cause of morbidity and mortality of adults around the world. In Diabetes and Hypertension: Evaluation and Management, a panel of renowned experts address a range of critical topics -- from basic concepts in evaluation and management of diabetes and hypertension, such as dietary interventions, to evaluation and management of secondary hypertension in clinical practice. Other chapters focus on high cardiovascular risk populations such as those with coronary heart disease, chronic kidney disease and minority patients. In addition, evolving concepts and new developments in the field are presented in other chapters, such as prevention of type 2 diabetes and the epidemic of sleep apnea and its implication for diabetes and hypertension evaluation and management. An important title covering two of the most troubling disorders of our time, Diabetes and Hypertension: Evaluation and Management will provide the busy practitioner with cutting edge knowledge in the field as well as practical information that can translate into better care provided to the high-risk population of diabetics and hypertensive patients.




Side Effects of Drugs


Book Description




Handbook of Hypertension


Book Description

When treating hypertension, physicians now have a huge range of drugs from which to choose in formulating a management strategy. This accessible guide helps the busy clinician access specific information on available drugs as components of an integrated care plan. The Handbook of Hypertension is a comprehensive review of the evidence base for hypertension and associated disease, providing tables, figures, charts, and summaries of principal findings from clinical studies on hypertension – putting vital information within reach of the busy practitioner. Containing the most recent guidelines for global cardiovascular risk analysis and evidence-based reviews on important new advances and recent trials, consulting the Handbook of Hypertension will save precious time and improve patient care.




Evidence-based Management of Hypertension


Book Description

The treatment of hypertension is now evolving into a decision-making process of ever greater complexity. Not only has the range of drugs available increased but so too has our knowledge of the diversity of individual patients' responsiveness to therapy, and the need to tailor their treatment with reference to a wide variety of additional factors. In order to provide effective patient care, the clinician needs to be aware of all the options available, but also of the evidence supporting their use and the extent to which that evidence justifies the choices made. In this new volume, leading authorities in their fields draw on the available evidence to provide answers to a series of key clinical questions facing the clinician treating hypertension: Should we treat prehypertension? How does the choice of therapy change in the presence of comorbidities such as obesity, ischemic heart disease, left ventricular hypertrophy, diabetes or cerebrovascular disease? Evidence-based Management of Hypertension provides answers to these and many other questions, as the authors present an expert analysis of the available evidence and offer authoritative recommendations for treatment planning. In each chapter, tables highlight evidence from a variety of sources, and every chapter concludes with a series of key practice points that present a summary of evidence-based recommendations for best practice, graded according to the quality of that evidence. For any clinician concerned with the care of the hypertensive patient, this volume will be a valuable aid to treatment planning and long-term management.




Antihypertensive Drugs


Book Description

Twenty US and European contributors from academia and pharmaceutical companies present a tripartite discussion of the short but impressive history of drug treatment of essential hypertension, focusing on: medicinal chemistry, pharmacology, and the clinical picture. Each successive generation of drugs (e.g. beta-blockers, calcium antagonists, and ACE-inhibitors) permits more precise tailoring to individual patient needs, as well as further elucidating the pathophysiology of the disease. Those interested in integrative medicine will appreciate the paper on treating hypertension in the elderly and diabetics, which refers to non-drug lifestyle approaches to lowering blood pressure. Annotation copyrighted by Book News, Inc., Portland, OR