Application of Data Mining in Pharmaceutical Research
Author : Zhenyu Pan
Publisher : Frontiers Media SA
Page : 115 pages
File Size : 21,54 MB
Release : 2024-03-07
Category : Science
ISBN : 2832545874
Pharmaceutical Data Mining
Author : Konstantin V. Balakin
Publisher : John Wiley & Sons
Page : 584 pages
File Size : 29,96 MB
Release : 2009-11-19
Category : Medical
ISBN : 0470567619
Book Description
Leading experts illustrate how sophisticated computational data mining techniques can impact contemporary drug discovery and development In the era of post-genomic drug development, extracting and applying knowledge from chemical, biological, and clinical data is one of the greatest challenges facing the pharmaceutical industry. Pharmaceutical Data Mining brings together contributions from leading academic and industrial scientists, who address both the implementation of new data mining technologies and application issues in the industry. This accessible, comprehensive collection discusses important theoretical and practical aspects of pharmaceutical data mining, focusing on diverse approaches for drug discovery—including chemogenomics, toxicogenomics, and individual drug response prediction. The five main sections of this volume cover: A general overview of the discipline, from its foundations to contemporary industrial applications Chemoinformatics-based applications Bioinformatics-based applications Data mining methods in clinical development Data mining algorithms, technologies, and software tools, with emphasis on advanced algorithms and software that are currently used in the industry or represent promising approaches In one concentrated reference, Pharmaceutical Data Mining reveals the role and possibilities of these sophisticated techniques in contemporary drug discovery and development. It is ideal for graduate-level courses covering pharmaceutical science, computational chemistry, and bioinformatics. In addition, it provides insight to pharmaceutical scientists, principal investigators, principal scientists, research directors, and all scientists working in the field of drug discovery and development and associated industries.
Computer Applications in Pharmaceutical Research and Development
Author : Sean Ekins
Publisher : John Wiley & Sons
Page : 840 pages
File Size : 49,7 MB
Release : 2006-07-11
Category : Medical
ISBN : 0470037229
Book Description
A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process. Chapters are organized into the following sections: * Computers in pharmaceutical research and development: a general overview * Understanding diseases: mining complex systems for knowledge * Scientific information handling and enhancing productivity * Computers in drug discovery * Computers in preclinical development * Computers in development decision making, economics, and market analysis * Computers in clinical development * Future applications and future development Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth. Finally, tables of software resources are provided in many of the chapters. This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET, drug discovery, and technology development. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.
Data Mining Applications with R
Author : Yanchang Zhao
Publisher : Academic Press
Page : 493 pages
File Size : 30,94 MB
Release : 2013-11-26
Category : Computers
ISBN : 0124115209
Book Description
Data Mining Applications with R is a great resource for researchers and professionals to understand the wide use of R, a free software environment for statistical computing and graphics, in solving different problems in industry. R is widely used in leveraging data mining techniques across many different industries, including government, finance, insurance, medicine, scientific research and more. This book presents 15 different real-world case studies illustrating various techniques in rapidly growing areas. It is an ideal companion for data mining researchers in academia and industry looking for ways to turn this versatile software into a powerful analytic tool. R code, Data and color figures for the book are provided at the RDataMining.com website. - Helps data miners to learn to use R in their specific area of work and see how R can apply in different industries - Presents various case studies in real-world applications, which will help readers to apply the techniques in their work - Provides code examples and sample data for readers to easily learn the techniques by running the code by themselves
Data Mining in Drug Discovery
Author : Rémy D. Hoffmann
Publisher : John Wiley & Sons
Page : 322 pages
File Size : 27,30 MB
Release : 2013-09-25
Category : Medical
ISBN : 3527656006
Book Description
Written for drug developers rather than computer scientists, this monograph adopts a systematic approach to mining scientifi c data sources, covering all key steps in rational drug discovery, from compound screening to lead compound selection and personalized medicine. Clearly divided into four sections, the first part discusses the different data sources available, both commercial and non-commercial, while the next section looks at the role and value of data mining in drug discovery. The third part compares the most common applications and strategies for polypharmacology, where data mining can substantially enhance the research effort. The final section of the book is devoted to systems biology approaches for compound testing. Throughout the book, industrial and academic drug discovery strategies are addressed, with contributors coming from both areas, enabling an informed decision on when and which data mining tools to use for one's own drug discovery project.
Medical Device Epidemiology and Surveillance
Author : S. Lori Brown
Publisher : John Wiley & Sons
Page : 528 pages
File Size : 17,15 MB
Release : 2007-03-13
Category : Medical
ISBN : 9780470060865
Book Description
Medical devices are crucial in medical care today and device technology advances at a dizzying pace. Medical Device Epidemiology and Surveillance is the first book to provide an overview of medical device epidemiology and surveillance as well as perspectives from regulatory agencies, the medical device industry, the health insurance industry and academia. The book is edited by experts from the US Food and Drug Administration with contributions from experienced specialists working in this field in the US and around the world. It features chapters describing broad themes in medical device epidemiology and surveillance, as well as chapters that describe specific medical devices. Medical Device Epidemiology and Surveillance is an essential reference for epidemiologists, pharmacoepidemiologists, academics, graduate students, and everybody working in the medical device industry.
Handbook of Statistical Analysis and Data Mining Applications
Author : Ken Yale
Publisher : Elsevier
Page : 824 pages
File Size : 49,85 MB
Release : 2017-11-09
Category : Mathematics
ISBN : 0124166458
Book Description
Handbook of Statistical Analysis and Data Mining Applications, Second Edition, is a comprehensive professional reference book that guides business analysts, scientists, engineers and researchers, both academic and industrial, through all stages of data analysis, model building and implementation. The handbook helps users discern technical and business problems, understand the strengths and weaknesses of modern data mining algorithms and employ the right statistical methods for practical application. This book is an ideal reference for users who want to address massive and complex datasets with novel statistical approaches and be able to objectively evaluate analyses and solutions. It has clear, intuitive explanations of the principles and tools for solving problems using modern analytic techniques and discusses their application to real problems in ways accessible and beneficial to practitioners across several areas—from science and engineering, to medicine, academia and commerce. - Includes input by practitioners for practitioners - Includes tutorials in numerous fields of study that provide step-by-step instruction on how to use supplied tools to build models - Contains practical advice from successful real-world implementations - Brings together, in a single resource, all the information a beginner needs to understand the tools and issues in data mining to build successful data mining solutions - Features clear, intuitive explanations of novel analytical tools and techniques, and their practical applications
Data Mining in Clinical Medicine
Author : Carlos Fernández Llatas
Publisher : Humana Press
Page : 0 pages
File Size : 46,43 MB
Release : 2014-11-24
Category : Science
ISBN : 9781493919840
Book Description
This volume complies a set of Data Mining techniques and new applications in real biomedical scenarios. Chapters focus on innovative data mining techniques, biomedical datasets and streams analysis, and real applications. Written in the highly successful Methods in Molecular Biology series format, chapters are thought to show to Medical Doctors and Engineers the new trends and techniques that are being applied to Clinical Medicine with the arrival of new Information and Communication technologies Authoritative and practical, Data Mining in Clinical Medicine seeks to aid scientists with new approaches and trends in the field.
Research and Trends in Data Mining Technologies and Applications
Author : Taniar, David
Publisher : IGI Global
Page : 340 pages
File Size : 36,54 MB
Release : 2006-10-31
Category : Computers
ISBN : 1599042738
Book Description
Activities in data warehousing and mining are constantly emerging. Data mining methods, algorithms, online analytical processes, data mart and practical issues consistently evolve, providing a challenge for professionals in the field. Research and Trends in Data Mining Technologies and Applications focuses on the integration between the fields of data warehousing and data mining, with emphasis on the applicability to real-world problems. This book provides an international perspective, highlighting solutions to some of researchers' toughest challenges. Developments in the knowledge discovery process, data models, structures, and design serve as answers and solutions to these emerging challenges.
Data Mining for Scientific and Engineering Applications
Author : R.L. Grossman
Publisher : Springer Science & Business Media
Page : 632 pages
File Size : 45,93 MB
Release : 2001-10-31
Category : Computers
ISBN : 9781402001147
Book Description
Advances in technology are making massive data sets common in many scientific disciplines, such as astronomy, medical imaging, bio-informatics, combinatorial chemistry, remote sensing, and physics. To find useful information in these data sets, scientists and engineers are turning to data mining techniques. This book is a collection of papers based on the first two in a series of workshops on mining scientific datasets. It illustrates the diversity of problems and application areas that can benefit from data mining, as well as the issues and challenges that differentiate scientific data mining from its commercial counterpart. While the focus of the book is on mining scientific data, the work is of broader interest as many of the techniques can be applied equally well to data arising in business and web applications. Audience: This work would be an excellent text for students and researchers who are familiar with the basic principles of data mining and want to learn more about the application of data mining to their problem in science or engineering.
