Biochemical Applications of Raman and Resonance Raman Spectroscopes


Book Description

Biochemical Applications of Raman and Resonance Raman Spectroscopies focuses on the application of Raman and resonance Raman spectroscopies to biochemical problems. The book reviews biological systems and details the application of Raman spectroscopy to biological molecules such as proteins, nucleic acids, and lipids. It also looks at codevelopments of lasers, optics, and electronics that drive advances in experimental Raman spectroscopy, along with the important ramifications of these advances for biochemical applications. This volume is organized into eight chapters and begins with an overview of the theoretical and experimental aspects of Raman spectroscopy, including a very brief explanation of what Raman and resonance Raman spectroscopies are and a discussion of their advantages and disadvantages for biochemical studies. The explanation of the Raman and resonance Raman effects is taken up in more detail in the next chapter, which develops the concept of the vibrational motions of molecules by initially considering mechanical ""ball and spring"" models and goes on to use this concept to formulate a classical model for Raman scattering. The resonance Raman effect is then described by another model which emphasizes the discrete or quantized energy levels available to a molecule. The reader is also introduced to the experimental aspects of Raman spectroscopy and the application of Raman spectroscopy across the entire field of biochemistry. Each chapter contains an outline of the basic chemistry and biochemical nomenclature involved. This book will be of interest to chemists, biochemists, and spectroscopists, as well as graduate students and experienced research workers.




Lasers in Polymer Science and Technolgy


Book Description

The purpose of this 4-volume set is to examine some of the applications of lasers in polymer science and technology. Now available for the first time, up-to-date information on this fascinating subject is compiled and presented in compact form. This set focuses on current research and developments in the application of lasers in polymer and biopolymer chemistry. It includes experimental and theoretical details, apparatus, techniques, and applications. This set is a useful source for researchers, students, polymer chemists, and physicists involved in this astonishing field of high technology.




Biomedical Spectroscopy


Book Description

This book discusses biomedical spectroscopy and the applications of spectroscopic techniques in advanced medical technology. Applicable to scientists and medical professionals, the aim of this work is to enable them to work together in this field, so that healthcare facilities can be made routinely available in a cost-effective manner—especially for developing countries which may not be able to afford universal healthcare with present day expensive medical technologies. The subject matter of this book also covers – Instrumentation, Experimental Techniques and Computational Methods Spectroscopy of Animal Models Microspectroscopy for Biomedical Applications Clinical Applications of Optical Spectroscopy Spectroscopy of Human Models Print edition not for sale in South Asia (India, Sri Lanka, Nepal, Bangladesh, Pakistan and Bhutan)




Infrared and Raman Spectroscopy of Biological Materials


Book Description

Infrared and Raman Spectroscopy of Biological Materials facilitates a comprehensive and through understanding of the latest developments in vibrational spectroscopy. It contains explains key breakthroughs in the methodologies and techniques for infrared, near-infrared, and Raman spectroscopy. Topics include qualitative and quantitative analysis, bi




Biomedical Engineering


Book Description

This book is addressed to scientists and professionals working in the wide area of biomedical engineering, from biochemistry and pharmacy to medicine and clinical engineering. The panorama of problems presented in this volume may be of special interest for young scientists, looking for innovative technologies and new trends in biomedical engineering.




Physical Methods to Characterize Pharmaceutical Proteins


Book Description

Proteins are still gaining importance in the pharmaceutical world, where they are used to improve our arsenal of therapeutic drugs and vaccines and as diagnostic tools. Proteins are different from "traditional" low-molecular-weight drugs. As a group, they exhibit a number of biopharmaceutical and formulation problems. These problems have drawn considerable interest from both industrial and aca demic environments, forcing pharmaceutical scientists to explore a domain previ ously examined only by peptide and protein chemists. Biopharmaceutical aspects of proteins, e.g., low oral bioavailability, have been extensively investigated. Although all possible conventional routes of ad ministration have been examined for proteins, no real, generally applicable alter native to parenteral administration in order to achieve systemic effects has yet been discovered. Several of these biopharmaceutical options have been discussed in Volume 4 of this series, Biological Barriers to Protein Delivery. Proteins are composed of many amino acids, several of which are notorious for their chemical instability. Rational design of formulations that optimize the native structure and/or bioactivity of a protein is therefore of great importance when long shelf life is required, as it is for pharmaceutical products. This issue has also been examined in two prior volumes of this series: Volume 2: Stability of Protein Pharmaceuticals (Part A) and Volume 5: Stability and Characterization of Protein and Peptide Drugs.




High Pressure Chemistry, Biochemistry and Materials Science


Book Description

This monograph, which is the outcome of the ASI on High Pressure Chemistry, Biochemistry, and Materials Science, illustrates new developments in the field of high pressure science. In fact, for chemists, biochemists, and materials scientists, pressure as an experimental variable represents a tool which provides unique information about systems of materials studied. It is interesting to note how the growth of the high pressure field is also reflected in the content of the recent ASI's dealing with this field. The ASI High Pressure Chemistry held in 1977 was followed by the ASI High Pressure Chemistry and Biochemistry held in 1986, and the coverage of the present ASI also includes applications to materials science. In view of the teaching character of the ASI, it is natural that main contributions to this volume present overviews of the different subfields or applications of high pressure research. In contrast, contributed papers offer more specialized aspects of various high pressure studies. The various contributions to this volume make clear the impressive range of fundamental and applied problems that can be studied by high pressure techniques, and also point towards a major growth of high pressure science and technology in the near future. This ASI focused mainly on advances achieved in the six years since the previous ASI devoted to the high pressure field. The organization of this volume is as follows.




Analytical Instrumentation Handbook, Second Edition


Book Description

Intended for both the novice and professional, this text aims to approach problems with currently available tools and methods in the modern analytical chemistry domain. It covers all fields from basic theory and principles of analytical chemistry to instrumentation classification, design and purchasing. This edition includes information on X-ray methods and analysis, capillary electrophoresis, infrared and Raman technique comparisons, and more.




Hayes' Principles and Methods of Toxicology, Sixth Edition


Book Description

Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.