Behavioral Neurobiology of Bipolar Disorder and its Treatment


Book Description

This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.




The Annenbergs


Book Description

"This is the colorful and dramatic biography of two of America's most controversial entrepreneurs: Moses Louis Annenberg, 'the racing wire king, ' who built his fortune in racketeering, invested it in publishing, and lost much of it in the biggest tax evasion case in United States history; and his son, Walter, launcher of TV Guide and Seventeen magazines and former ambassador to Great Britain."--Jacket.




The Natural History of Mania, Depression, and Schizophrenia


Book Description

The Natural History of Mania, Depression, and Schizophrenia takes an unusual look at the course of mental illness, based on data from the Iowa 500 Research Project. This project involved the long-term (30-40 years) follow-up of patients diagnosed with schizophrenia, depression, and bipolar illness. After presenting a history and background of the study, the authors provide fascinating, verbatim interviews with patients at the time of hospital admission in the 1930s and 1940s. Eight of the 15 chapters are dedicated to the modern, systematic follow-up and family study of these patients. Medical students, residents, psychiatrists, social workers, psychologists, ministers, and clinicians are offered an interesting look at what might be expected should treatment not be instituted with such patients. Unlike earlier works that focused on the descriptive aspects of mental illness, this book provides clinicians with a more systematic evaluation of the symptom picture, course and outcome, and family history. It concludes with useful information on the diagnosis and classification of the affective disorders and chronic nonaffective psychoses.




The New Jersey Law Journal


Book Description

Vols. 4-17 include General public acts passed by the 105th - 118th Legislature of the state of New Jersey and lists of members of the Legislature.




Neurobiology of Bipolar Disorder


Book Description

The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. - Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations - Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics - Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder




Bipolar Disorders


Book Description

Biopolar disorder has served as a principal point of focus for modern psychiatric research since the advent of the psychopharmacological revolution. Yet, the disparity between optimal and typical care for biopolar disorder is perhaps nowhere larger, and its human and economic impact nowhere greater. An important and much-needed resource, Bipolar Disorders: Clinical Course and Outcome relates empirical data on outcome with practical information on the prognosis, course, and potential complications of bipolar disorders in the modern era. Pulling together current knowledge on bipolar disorders from leading investigators in the field, Bipolar Disorders provides a concise, up-to-date summary of affective relapse, comorbid psychopathology, functional disability, and psychosocial outcome in contemporary bipolar disorders. Important issues regarding pharmacoeconomics and the burden of disease are presented in conjunction with a discussion of mania through the life cycle and a summary of clinical and treatment implications. In addition, this timely resource covers the effect of lithium and anticonvulsants on outcome during controlled and naturalistic treatment; manic outcome in relation to specific comorbidities or subtypes of illness for mixed mania, alcoholism or other substance abuse, rapid-cycling bipolar disorders, hypomania, and comorbid anxiety disorders; individual psychotherapy and family psychoeducation; and the role of public sector psychiatry and community-based treatment programs for chronic bipolar illness. As part of the Clinical Practice Series of the American Psychiatric Press, this book integrates current clinical research findings with practical clinical applications, providing a broad overview of course and outcome for bipolar patients treated under typical treatment conditions. Aimed at both clinicians and investigators, this book consciously relates naturalistic follow-up studies in mania to the routine clinical management of bipolar disorders over time.