Author : Dana G. Dalrymple
Publisher :
Page : 253 pages
File Size : 18,93 MB
Release : 2013
Category : Malaria
ISBN : 9780615615998
This book is a comprehensive review and analysis of the origin, development and use of the most effective drug treatment for malaria in Africa.
Author : Institute of Medicine
Publisher : National Academies Press
Page : 384 pages
File Size : 15,82 MB
Release : 2004-09-09
Category : Medical
ISBN : 0309165938
For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called "artemisinins" are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.
Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
Page : 848 pages
File Size : 39,58 MB
Release : 1999
Category : Medical
ISBN : 9780781719520
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author : Youyou Tu
Publisher : Academic Press
Page : 470 pages
File Size : 35,44 MB
Release : 2017-07-08
Category : Science
ISBN : 0128116560
Approx.426 pages Approx.426 pages
Author : Program on Forced Migration and Health at the Mailman School of Public Health of Columbia University
Publisher : National Academies Press
Page : 181 pages
File Size : 20,69 MB
Release : 2003-01-16
Category : Medical
ISBN : 0309086159
Admittedly, the world and the nature of forced migration have changed a great deal over the last two decades. The relevance of data accumulated during that time period can now be called into question. The roundtable and the Program on Forced Migration at the Mailman School of Public Health of Columbia University have commissioned a series of epidemiological reviews on priority public health problems for forced migrants that will update the state of knowledge. Malaria Control During Mass Population Movements and Natural Disasters- the first in the series, provides a basic overview of the state of knowledge of epidemiology of malaria and public health interventions and practices for controlling the disease in situations involving forced migration and conflict.
Author : Tariq Aftab
Publisher : CRC Press
Page : 340 pages
File Size : 32,1 MB
Release : 2017-12-14
Category : Health & Fitness
ISBN : 1351802860
Artemisia annua is a well-known medicinal plant that has been utilized for a number of purposes, including malaria, for centuries. This is the first comprehensive book to cover the importance of Artemisia annua in the global health crisis and in the treatment against diseases. A component and extract, artemisinin, is the source of other derivatives which are also suitable for pharmaceutical use. The present demand for artemisinin far outpaces its supply. Researchers are working globally towards improving artemisinin content in the plant by various means. Artemisia annua: Prospects, Applications and Therapeutic Uses highlights the different approaches, including ‘omics', that are being used in current research on this immensely important medicinal plant. Providing comprehensive coverage of the agricultural and pharmaceutical uses of this plant, Artemisia annua will be essential reading for botanists, plant scientists, herbalists, pharmacognosists, pharmacologists and natural product chemists.
Author : Mahendra Rai
Publisher : Academic Press
Page : 291 pages
File Size : 25,58 MB
Release : 2013-05-24
Category : Science
ISBN : 0124017088
Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more
Author : Institute of Medicine
Publisher : National Academies Press
Page : 312 pages
File Size : 50,22 MB
Release : 1991-02-01
Category : Medical
ISBN : 9780309045278
Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.
Author : Tariq Aftab
Publisher : Springer Science & Business Media
Page : 288 pages
File Size : 35,25 MB
Release : 2013-11-26
Category : Science
ISBN : 3642410278
Artemisinin, a sesquiterpene lactone originally extracted from the medicinal plant Artemisia annua L., is an effective antimalarial agent, particularly for multi-drug resistant and cerebral malaria. However, the concentration of artemisinin in the plant is very low. Because the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source of artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A. annua to reduce the cost of artemisinin based antimalarial drugs. Plant scientists have focused their efforts on A. annua for a higher artemisinin crop yield. With the present volume, we are bringing together the research which is being done on this plant throughout the world and future possibilities for scientists and researchers who want to work on it.
Author : Merlin Willcox
Publisher : CRC Press
Page : 464 pages
File Size : 26,75 MB
Release : 2004-06-28
Category : Health & Fitness
ISBN : 0203502329
Malaria is an increasing worldwide threat, with more than three hundred million infections and one million deaths every year. The worlds poorest are the worst affected, and many treat themselves with traditional herbal medicines. These are often more available and affordable, and sometimes are perceived as more effective than conventional antimala
