Haschek and Rousseaux's Handbook of Toxicologic Pathology


Book Description

Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. - Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations




Haschek and Rousseaux's Handbook of Toxicologic Pathology, Volume 1: Principles and Practice of Toxicologic Pathology


Book Description

Haschek and Rousseaux's Handbook of Toxicologic Pathology, recognized by many as the most authoritative single source of information in the field of toxicologic pathology, has been extensively updated to continue its comprehensive and timely coverage. The fourth edition has been expanded to four separate volumes due to an explosion of information in this field requiring new and updated chapters. Completely revised with a number of new chapters, Volume 1, "Principles and the Practice of Toxicologic Pathology," covers the practice of toxicologic pathology in three parts: Principles of Toxicologic Pathology, Methods in Toxicologic Pathology, and the Practice of Toxicologic Pathology. Other volumes in this work round out the depth and breadth of coverage.Volume 2 encompasses "Toxicologic Pathology in Safety Assessment" and "Environmental Toxicologic Pathology". These two sections cover the application of toxicologic pathology in developing specific product classes, principles of data interpretation for safety assessment, and toxicologic pathology of major classes of environmental toxicants. Volumes 3 and 4 provide deep and broad treatment of "Target Organ Toxicity", emphasizing the comparative and correlative aspects of normal biology and toxicant-induced dysfunction, principal methods for toxicologic pathology evaluation, and major mechanisms of toxicity. These volumes comprise the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants. Each volume is being published separately. - Provides new chapters on digital pathology, juvenile pathology, in vitro/in vivo correlation, big data technologies and in-depth discussion of timely topics in the area of toxicologic pathology - Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology - Features hundreds of full-color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations







An Atlas of Comparative Vertebrate Histology


Book Description

Atlas of Comparative Vertebrate Histology looks at the histology of a wide range of vertebrates, representative of all the major classes and families, with examples ranging from amphioxus to primates. The authors focus their microscope on commonly seen vertebrates as well as 'non-standard' species, such as lamprey, hagfish, dogfish, skate, rock bass, cod, river catfish, toad, amphiuma, leopard and bull frog, garter and brown snake, Coturnix quail and cowbird. The study of comparative histology in the vertebrates helps students and researchers alike understand how various groups have addressed similar problems, opening doors to interesting research possibilities. Not all vertebrates follow the mammalian model of tissue and organ structure. When dealing with unique species, we see some structures taken beyond their 'normal' function. Comparative histology allows us to understand the structural responses underlying the physiology unique to each vertebrate group. - Presents the histology of a wide range of vertebrates, representative of all the major classes and families, with examples ranging from amphioxus to primates - Includes an image gallery with over 500 flat images and 50+ virtual microscopy slides - Contains electronic content features cross linking between text, tables and the image gallery




Fish Disease


Book Description

Fish Disease: Diagnosis and Treatment, Second Edition provides thorough, yet concise descriptions of viral, bacterial, fungal, parasitic and noninfectious diseases in an exhaustive number of fish species. Now in full color with over 500 images, the book is designed as a comprehensive guide to the identification and treatment of both common and rare problems encountered during the clinical work-up. Diseases are discussed following a systems-based approach to ensure a user-friendly and practical manual for identifying problems. Fish Disease: Diagnosis and Treatment, Second Edition is the must-have reference for any aquaculturists, aquatic biologists, or fish health specialists dealing with diagnosing or treating fish diseases.




Tilapia lake virus disease strategy manual


Book Description

The purpose of this manual is to inform national policymakers and other stakeholders of issues related to the development of contingency plans for responding to outbreaks of tilapia lake virus disease (TiLVD), which has caused substantial mortalities, up to 90 percent, in populations of both wild and farmed tilapia in Asia, the Americas, and Africa. The causative agent for this disease is tilapia lake virus (TiLV), which infects the liver, spleen, kidney, heart, gill tissues, brain, connective tissues of muscle, and reproductive organs of tilapia. Outbreaks of TiLVD not only have devastating economic effects on producers, but also can result in a variety of socio-economic impacts on surrounding communities. It would, therefore, be prudent to implement strategies for the prevention of TiLVD and to develop contingency plans to eradicate, contain, and mitigate the impacts of the disease when outbreaks occur. This manual provides information on: 1) the nature of TiLVD; 2) diagnosis; 3) prevention and control; 4) epidemiology; 5) principles of eradication, containment and mitigation; and 6) policy development issues.




Atlas of Fish Histology


Book Description

Many books emphasize the pathological histology of fish, but this volume fills a gap in the literature by focusing on normal fish histology. A general reference guide, it provides an extensive set of histological images of fish, discussing approximately 40 species. The book presents histology as a discipline--including its methodology and techniques--and its goals of investigating the structure and function of tissue samples. By histologically examining the normal physiology of fish tissue, scientists can gain insight into signs of disease not easily recognized on gross examination.







Crustacean Nutrition


Book Description