Modern Techniques in Cytopathology


Book Description

In the era of precision medicine, physicians are increasingly in need of more definitive diagnostic, prognostic, and predictive information derived from small biopsy specimens such as cytology samples in order to guide effective patient care. Cytopathology is well poised to meet this challenge. Whilst the traditional cytomorphologic component of cytology practice is still valid, enormous advances have been made in the field of cytopathology thanks to transformative technology and innovative individuals that have augmented the cytologists' ability to meet the demands of modern medicine. The purpose of this book is to describe, illustrate, and review many of the most recent developments regarding modern techniques employed in cytopathology. This latest monograph is intended for all cytologists including cytopathologists, cytotechnologists, cytology lab assistants, trainees, research scientists, and anyone who is interested in the field of cytopathology. We have invited pioneering experts in their respective fields to author these chapters. This book is not only the culmination of their groundbreaking work and effort but also presents a critical review of the current literature. We have attempted to provide readers with an informative and comprehensive aid so that they may better appreciate how emerging technology has been applied to cytology. Each chapter in this book presents a stand-alone contemporary review of emerging topics in cytopathology. We hope that you will find this monograph thought-provoking and a valuable reference for your practice.







The Bethesda System for Reporting Cervical Cytology


Book Description

This book offers clear, up-to-date guidance on how to report cytologic findings in cervical, vaginal and anal samples in accordance with the 2014 Bethesda System Update. The new edition has been expanded and revised to take into account the advances and experience of the past decade. A new chapter has been added, the terminology and text have been updated, and various terminological and morphologic questions have been clarified. In addition, new images are included that reflect the experience gained with liquid-based cytology since the publication of the last edition in 2004. Among more than 300 images, some represent classic examples of an entity while others illustrate interpretative dilemmas, borderline cytomorphologic features or mimics of epithelial abnormalities. The Bethesda System for Reporting Cervical Cytology, with its user-friendly format, is a “must have” for pathologists, cytopathologists, pathology residents, cytotechnologists, and clinicians.




Basic and Advanced Laboratory Techniques in Histopathology and Cytology


Book Description

The second edition of this well-received book provides detailed information on the basic and advanced laboratory techniques in histopathology and cytology. It offers clear guidance on the principles and techniques of routine and special laboratory techniques. It also covers advanced laboratory techniques such as immunocytochemistry, flow cytometry, liquid-based cytology, polymerase chain reactions, tissue microarray, molecular technology, etc. The book's second edition covers several important recent topics with many new chapters, such as liquid biopsy, artificial neural network, digital pathology, and next-generation sequencing. Each chapter elucidates basic principle, practical methods, troubleshooting, and clinical applications of the technique. It includes multiple colored line drawings, microphotographs, and tables to illustrate each technique. The book is a helpful guide to the post-graduate students and fellows in pathology, practicing pathologists, as well as laboratory technicians, and research students.




Whole Slide Imaging


Book Description

This book provides up-to-date and practical knowledge in all aspects of whole slide imaging (WSI) by experts in the field. This includes a historical perspective on the evolution of this technology, technical aspects of making a great whole slide image, the various applications of whole slide imaging and future applications using WSI for computer-aided diagnosis The goal is to provide practical knowledge and address knowledge gaps in this emerging field. This book is unique because it addresses an emerging area in pathology for which currently there is only limited information about the practical aspects of deploying this technology. For example, there are no established selection criteria for choosing new scanners and a knowledge base with the key information. The authors of the various chapters have years of real-world experience in selecting and implementing WSI solutions in various aspects of pathology practice. This text also discusses practical tips and pearls to address the selection of a WSI vendor, technology details, implementing this technology and provide an overview of its everyday uses in all areas of pathology. Chapters include important information on how to integrate digital slides with laboratory information system and how to streamline the “digital workflow” with the intent of saving time, saving money, reducing errors, improving efficiency and accuracy, and ultimately benefiting patient outcomes. Whole Slide Imaging: Current Applications and Future Directions is designed to present a comprehensive and state-of the-art approach to WSI within the broad area of digital pathology. It aims to give the readers a look at WSI with a deeper lens and also envision the future of pathology imaging as it pertains to WSI and associated digital innovations.







European Guidelines for Quality Assurance in Cervical Cancer Screening


Book Description

Recoge: 1. Epidemiological guidelines for quality assurance in cervical cancer screening - 2. Methods for screening and diagnosis - 3. Laboratory guidelines and quality assurance practices for cytology - 4. Techniques and quality assurance guidelines for histopathology - 5. Management of abnormal cervical cytology - 6. Key performance indicators - 7. Annexes.




Comprehensive Cytopathology E-Book


Book Description

This best-selling book provides you with a comprehensive guide to the diagnostic applications of exfoliative and aspiration cytology. The book takes a systemic approach and covers the recognized normal and abnormal cytological findings encountered in a particular organ. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. The book is lavishly illustrated, making it the perfect practical resource for daily reference in the laboratory. Provides an accessible guide to diagnostic investigation and screening. Includes a summary of major diagnostic criteria and discusses the pitfalls and limitations of cytology. Utilizes a consistent chapter structure to make finding the answers you need quick and easy. Provides updates to crucial chapters to keep you on top of the latest diagnosis and techniques. Incorporates differential diagnosis tables for easy comparison/contrast of diagnoses. Offers more than 1800 full-color images depicting a full range of normal and abnormal findings. Discusses new concepts on molecular basis of neoplasia. Explores the role of cytogenetics in cancer development.




Diagnostic Cytopathology


Book Description

Diagnostic Cytopathology provides the clinician with a comprehensive guide to the diagnostic applications of exfoliative and aspiration cytology. The book takes a systemic approach and will cover the recognised normal and abnormal cytological findings encountered in a particular organ. Appropriate histopathological correlations and a consideration of the possible differential diagnosis accompany the cytological findings. The book is heavily illustrated to ensure that it will be a practical resource for daily reference in the laboratory. A uniformity of basic chapter structure will expedite the clinician's search for answers to any query. in-depth bench book that covers everyday diagnostic work. Provides the clinician with an accessible guide to diagnostic investigation and screening. Cytologic findings closely related to histology. Provides the general diagnostic pathologist in the interpretation and recognition of tissue samples. Each chapter provides a summary of major diagnostic criteria and discusses the pitfalls and limitations of cytology. Enables the clinician to use cytology services more effectively. Major revisions of the following chapters: Mesotheliomas, Malignant Breast Tumours, Lymph Nodes, The Pathogenesis of Cervical Neoplasia, Cervical intraepithelial neoplasia and Squamous Carcinoma of the Cervix. Brand new chapter on Automation which is increasingly important in cervical screening. Additional material on Thin Core Biopsy technique which is increasingly used in Breast Screening Program. Inclusion of new genetic markers in immunohistochemistry increasingly important in non-gynaecological areas. With 47 additional contributors.