› › Azoles

Azoles

Author : Aleksey Kuznetsov

Publisher : BoD – Books on Demand

Page : 148 pages

File Size : 20,43 MB

Release : 2021-06-30

Category : Science

ISBN : 1839681799

Get eBook

Book Description

Azoles are a broad and promising class of five-membered heterocyclic compounds containing from one up to five nitrogen atom(s) that can also contain sulfur or oxygen atoms. Widely used as potent antifungal agents, various azole derivatives have also demonstrated many other promising biological properties. This book covers studies of several types of thiazole-based heterocyclic scaffolds, the development of 4-thiazolidinone and thiazole derivatives with heterocyclic fragments as potential candidates for new drugs against trypanosomiasis, numerous synthetic approaches for the synthesis of 1,2,3-triazoles, the application of N-azole, N,S-azole, and N,O-azole as well as their derivatives as retarders of metallic corrosion, and the integration of azoles in materials used for renewable energy processing and applications and wood treatment.



Handbook of Antimicrobial Resistance

Author : Matthias Gotte

Publisher : Springer

Page : 0 pages

File Size : 15,49 MB

Release : 2018-02-12

Category : Medical

ISBN : 9781493906932

Get eBook

Book Description

While many volumes have been written about various aspects of antimicrobial resistance, this book is a comprehensive reference work. All manifestations of resistance are addressed: viral; bacterial, parasitical and fungal are given dedicated sections. The underlining molecular mechanisms, which depend not only on the microbe but on the specific drug (target), are highly diverse. This work discusses and compares the biological, biochemical and structural aspects of resistance and its evolution.



Antifungal Therapy

Author : Mahmoud Ghannoum

Publisher : CRC Press

Page : 484 pages

File Size : 25,47 MB

Release : 2016-04-19

Category : Medical

ISBN : 0849387868

Get eBook

Book Description

A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a c





Hepatotoxicity

Author : Hyman J. Zimmerman

Publisher : Lippincott Williams & Wilkins

Page : 850 pages

File Size : 15,9 MB

Release : 1999

Category : Medical

ISBN : 9780781719520

Get eBook

Book Description

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.



Nitroazoles: Synthesis, Structure and Applications

Author : Lyudmila Larina

Publisher : Springer Science & Business Media

Page : 454 pages

File Size : 48,64 MB

Release : 2009-08-28

Category : Science

ISBN : 0387980709

Get eBook

Book Description

This volume is devoted to the synthesis, application, structure, and physicochemical properties of nitroazoles (five-membered aromatic compounds). The book is unique in providing the first comprehensive treatment of nitroazoles.



Clinical Small Animal Internal Medicine

Author : David Bruyette

Publisher : John Wiley & Sons

Page : 5143 pages

File Size : 37,81 MB

Release : 2020-03-25

Category : Medical

ISBN : 1118497031

Get eBook

Book Description

Clinical Small Animal Internal Medicine is a comprehensive, practical reference designed to meet the needs of veterinary practitioners and students alike. Covering all aspects of small animal internal medicine, this innovative guide provides clinically relevant material, plus podcasts and continual updates online. Concise, identically-formatted chapters allow readers to quickly find the most essential information for clinical veterinary practice. Contributions from academic and clinical experts cover general medicine subjects, including patient evaluation and management, critical care medicine, preventative care, and diagnostic and therapeutic considerations. Topics relevant to daily clinical practice are examined in detail, ranging from endocrine, cardiovascular, respiratory, and infectious disease to oncology, dermatology, metabolic orthopedic disease, gastroenterology, and hepatology. A companion website features podcasts and updated information. An important addition to the library of any practice, this clinically-oriented text: Presents complete, practical information on small animal internal medicine Provides the background physiology required to understand normal versus abnormal in real-world clinical settings Includes general medicine topics not covered in other internal medicine books Focuses on information that is directly applicable to daily practice Features podcasts and continual updates on a companion website Carefully tailored for the needs of small animal practitioners and veterinary students, Clinical Small Animal Internal Medicine is an invaluable, reader-friendly reference on internal medicine of the dog and cat.



Epidemiology

Author : Leon Gordis

Publisher : Elsevier Health Sciences

Page : 392 pages

File Size : 34,14 MB

Release : 2008-07-02

Category : Medical

ISBN : 1437700519

Get eBook

Book Description

This popular book is written by the award-winning teacher, Dr. Leon Gordis of the Bloomberg School of Public Health at Johns Hopkins University. He introduces the basic principles and concepts of epidemiology in clear, concise writing and his inimitable style. This book provides an understanding of the key concepts in the following 3 fully updated sections: Section I: The Epidemiologic Approach to Disease and Intervention; Section II: Using Epidemiology to Identify the Causes of Disease; Section III: Applying Epidemiology to Evaluation and Policy. Clear, practical graphs and charts, cartoons, and review questions with answers reinforce the text and aid in comprehension. Utilizes new full-color format to enhance readability and clarity. Provides new and updated figures, references and concept examples to keep you absolutely current - new information has been added on Registration of Clinical Trials, Case-Cohort Design, Case-Crossover Design, and Sources and Impact of Uncertainty (disease topics include: Obesity, Asthma, Thyroid Cancer, Helicobacter Pylori and gastric/duodenal ulcer and gastric cancer, Mammography for women in their forties) - expanded topics include Person-time. Please note: electronic rights were not granted for several images in this product. Introduces both the underlying concepts as well as the practical uses of epidemiology in public health and in clinical practice. Systemizes learning and review with study questions in each section and an answer key and index. Illustrates textual information with clear and informative full-color illustrations, many created by the author and tested in the classroom.



Heterocyclic Chemistry At A Glance

Author : John A. Joule

Publisher : John Wiley & Sons

Page : 332 pages

File Size : 33,23 MB

Release : 2012-08-06

Category : Science

ISBN : 1118380193

Get eBook

Book Description

This expanded second edition provides a concise overview of the main principles and reactions of heterocyclic chemistry for undergraduate students studying chemistry and related courses. Using a successful and student-friendly "at a glance" approach, this book helps the student grasp the essence of heterocyclic chemistry, ensuring that they can confidently use that knowledge when required. The chapters are thoroughly revised and updated with references to books and reviews; extra examples and student exercises with answers online; and color diagrams that emphasize exactly what is happening in the reaction chemistry depicted.



Principles of Pharmacology

Author : David E. Golan

Publisher : Lippincott Williams & Wilkins

Page : 1012 pages

File Size : 47,37 MB

Release : 2008

Category : Medical

ISBN : 9780781783552

Get eBook

Book Description

This primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective for diseases in that organ system. Over 400 two-color illustrations show molecular, cellular, biochemical, and pathophysiologic processes underlying diseases and depict targets of drug therapy. Each Second Edition chapter includes a drug summary table presenting mechanism, clinical applications, adverse effects, contraindications, and therapeutic considerations. New chapters explain how drugs produce adverse effects and describe the life cycle of drug development. The fully searchable online text and an image bank are available on thePoint.