Book Description
The first book to systematically introduce the emerging area of phylogenetic combinatorics.
Author : Andreas Dress
Publisher : Cambridge University Press
Page : 277 pages
File Size : 35,76 MB
Release : 2012
Category : Mathematics
ISBN : 0521768322
The first book to systematically introduce the emerging area of phylogenetic combinatorics.
Author : Mike Steel
Publisher : SIAM
Page : 302 pages
File Size : 20,30 MB
Release : 2016-09-29
Category : Science
ISBN : 161197447X
Phylogenetics is a topical and growing area of research. Phylogenies (phylogenetic trees and networks) allow biologists to study and graph evolutionary relationships between different species. These are also used to investigate other evolutionary processes?for example, how languages developed or how different strains of a virus (such as HIV or influenza) are related to each other. This self-contained book addresses the underlying mathematical theory behind the reconstruction and analysis of phylogenies. The theory is grounded in classical concepts from discrete mathematics and probability theory as well as techniques from other branches of mathematics (algebra, topology, differential equations). The biological relevance of the results is highlighted throughout. The author supplies proofs of key classical theorems and includes results not covered in existing books, emphasizes relevant mathematical results derived over the past 20 years, and provides numerous exercises, examples, and figures.
Author : Guillaume Fertin
Publisher : MIT Press
Page : 305 pages
File Size : 11,58 MB
Release : 2009
Category : Combinatorial analysis
ISBN : 0262062828
A comprehensive survey of a rapidly expanding field of combinatorial optimization, mathematically oriented but offering biological explanations when required. From one cell to another, from one individual to another, and from one species to another, the content of DNA molecules is often similar. The organization of these molecules, however, differs dramatically, and the mutations that affect this organization are known as genome rearrangements. Combinatorial methods are used to reconstruct putative rearrangement scenarios in order to explain the evolutionary history of a set of species, often formalizing the evolutionary events that can explain the multiple combinations of observed genomes as combinatorial optimization problems. This book offers the first comprehensive survey of this rapidly expanding application of combinatorial optimization. It can be used as a reference for experienced researchers or as an introductory text for a broader audience. Genome rearrangement problems have proved so interesting from a combinatorial point of view that the field now belongs as much to mathematics as to biology. This book takes a mathematically oriented approach, but provides biological background when necessary. It presents a series of models, beginning with the simplest (which is progressively extended by dropping restrictions), each constructing a genome rearrangement problem. The book also discusses an important generalization of the basic problem known as the median problem, surveys attempts to reconstruct the relationships between genomes with phylogenetic trees, and offers a collection of summaries and appendixes with useful additional information.
Author : Dan Gusfield
Publisher : MIT Press
Page : 601 pages
File Size : 17,9 MB
Release : 2014-07-03
Category : Mathematics
ISBN : 0262027526
When a Philadelphia girl intercepts a message about an impending British attack against her father's regiment, commanded by General Washington, in White Marsh, she travels alone by horseback to warn the Patriot army.
Author : Charles Semple
Publisher : Oxford University Press on Demand
Page : 258 pages
File Size : 41,74 MB
Release : 2003
Category : Computers
ISBN : 9780198509424
'Phylogenetics' is the reconstruction and analysis of phylogenetic (evolutionary) trees and networks based on inherited characteristics. It is a flourishing area of intereaction between mathematics, statistics, computer science and biology.The main role of phylogenetic techniques lies in evolutionary biology, where it is used to infer historical relationships between species. However, the methods are also relevant to a diverse range of fields including epidemiology, ecology, medicine, as well as linguistics and cognitive psychologyThis graduate-level book, based on the authors lectures at The University of Canterbury, New Zealand, focuses on the mathematical aspects of phylogenetics. It brings together the central results of the field (providing proofs of the main theorem), outlines their biological significance,and indicateshow algorithms may be derived. The presentation is self-contained and relies on discrete mathematics with some probability theory. A set of exercises and at least one specialist topic ends each chapter.This book is intended for biologists interested in the mathematical theory behind phylogenetic methods, and for mathematicians, statisticians, and computer scientists eager to learn about this emerging area of discrete mathematics.'Phylogenetics' in the 24th volume in the Oxford Lecture Series in Mathematics and its Applications. This series contains short books suitable for graduate students and researchers who want a well-written account of mathematics that is fundamental to current to research. The series emphasises futuredirections of research and focuses on genuine applications of mathematics to finance, engineering and the physical and biological sciences.
Author : L. Pachter
Publisher : Cambridge University Press
Page : 440 pages
File Size : 18,11 MB
Release : 2005-08-22
Category : Mathematics
ISBN : 9780521857000
This book, first published in 2005, offers an introduction to the application of algebraic statistics to computational biology.
Author : Adrian-Horia Dediu
Publisher : Springer
Page : 285 pages
File Size : 39,83 MB
Release : 2014-06-07
Category : Computers
ISBN : 3319079530
This book constitutes the refereed proceedings of the First International Conference, AlCoB 2014, held in July 2014 in Tarragona, Spain. The 20 revised full papers were carefully reviewed and selected from 39 submissions. The scope of AlCoB includes topics of either theoretical or applied interest, namely: exact sequence analysis, approximate sequence analysis, pairwise sequence alignment, multiple sequence alignment, sequence assembly, genome rearrangement, regulatory motif finding, phylogeny reconstruction, phylogeny comparison, structure prediction, proteomics: molecular pathways, interaction networks, transcriptomics: splicing variants, isoform inference and quantification, differential analysis, next-generation sequencing: population genomics, metagenomics, metatranscriptomics, microbiome analysis, systems biology.
Author : Pamela E. Harris
Publisher : Springer Nature
Page : 334 pages
File Size : 28,22 MB
Release : 2020-04-17
Category : Mathematics
ISBN : 3030378535
This volume provides accessible and self-contained research problems designed for undergraduate student projects, and simultaneously promotes the development of sustainable undergraduate research programs. The chapters in this work span a variety of topical areas of pure and applied mathematics and mathematics education. Each chapter gives a self-contained introduction on a research topic with an emphasis on the specific tools and knowledge needed to create and maintain fruitful research programs for undergraduates. Some of the topics discussed include:• Disease modeling• Tropical curves and surfaces• Numerical semigroups• Mathematics EducationThis volume will primarily appeal to undergraduate students interested in pursuing research projects and faculty members seeking to mentor them. It may also aid students and faculty participating in independent studies and capstone projects.
Author : Raul Rabadan
Publisher : Cambridge University Press
Page : 521 pages
File Size : 29,14 MB
Release : 2019-12-19
Category : Mathematics
ISBN : 1107159547
An introduction to geometric and topological methods to analyze large scale biological data; includes statistics and genomic applications.
Author : Celine Scornavacca
Publisher : Springer Nature
Page : 275 pages
File Size : 41,8 MB
Release : 2024
Category : Bioinformatics
ISBN : 3031580729
This book constitutes the proceedings of the 21st International Conference on Comparative Genomics, RECOMB-CG 2024, which was held in Boston, MA, USA, during April 27-28, 2024. The 13 full papers presented in this book were carefully reviewed and selected from 21 submissions. The papers are divided into the following topical sections: phylogenetic networks; homology and phylogenetic reconstruction; tools for evolution reconstruction; genome rearrangements; and genome evolution.