Basic Sciences of Nuclear Medicine


Book Description

This book provides comprehensive and detailed information on the scientific bases of nuclear medicine, addressing a wide variety of topics and explaining the concepts that underlie many of the investigations and procedures performed in the field. The book is divided into six sections that cover the physics and chemistry of nuclear medicine besides associated quality assurance/quality control procedures; dosimetry and radiation biology; SPECT and PET imaging instrumentation plus CT imaging technology in hybrid modalities; data analysis including image processing, reconstruction, radiomics, image degrading correction techniques, along with image quantitation and kinetic modeling. Within these sections, particular attention is paid to recent developments and the advances in knowledge that have taken place since release of the first edition in 2011. Several entirely new chapters have been included and the remaining chapters, thoroughly updated. Innovations in the ever-expanding field of nuclear medicine are predominantly due to integration of the basic sciences with complex technological advances. This excellently illustrated book on the subject will be of interest to not only nuclear medicine physicists and physicians but also clinical scientists, radiologists, radiopharmacists, medical students and technologists.




Basic Sciences of Nuclear Medicine


Book Description

Nuclear medicine has become an ever-changing and expanding diagnostic and therapeutic medical profession. The day-to-day innovations seen in the field are, in great part, due to the integration of many scientific bases with complex technologic advances. The aim of this reference book, Basic Sciences of Nuclear Medicine, is to provide the reader with a comprehensive and detailed discussion of the scientific bases of nuclear medicine, covering the different topics and concepts that underlie many of the investigations and procedures performed in the field. Topics include radiation and nuclear physics, Tc-99m chemistry, single-photon radiopharmaceuticals and PET chemistry, radiobiology and radiation dosimetry, image processing, image reconstruction, quantitative SPECT imaging, quantitative cardiac SPECT, small animal imaging (including multimodality hybrid imaging, e.g., PET/CT, SPECT/CT, and PET/MRI), compartmental modeling, and tracer kinetics.




Advancing Nuclear Medicine Through Innovation


Book Description

Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.




Essential Nuclear Medicine Physics


Book Description

Essential Nuclear Medicine Physics provides an excellent introduction to the basic concepts of the daunting area of nuclear physics. Logically structured and clearly written, this is the book of choice for anyone entering the field of nuclear medicine, including nuclear medicine residents and fellows, cardiac nuclear medicine fellows and nuclear medicine technology students. The text is also a handy quick-reference guide for those already working in the field of nuclear physics. This new edition provides a basic introduction to nuclear physics and the interactions of radiation and matter. The authors also provide comprehensive coverage of instrumentation and imaging, with separate chapters devoted to SPECT, PET, and PET/CT. Discussion of radiation biology, radiation safety and care of victims of radiation accidents completes the text, with an appendix containing the latest NRC rules and regulations. Essential Nuclear Medicine Physics presents difficult concepts clearly and concisely, defines all terminology for the reader, and facilitates learning through extensive illustrations and self-assessment questions.




Essentials of Nuclear Medicine and Molecular Imaging E-Book


Book Description

Covering both the fundamentals and recent developments in this fast-changing field, Essentials of Nuclear Medicine and Molecular Imaging, 7th Edition, is a must-have resource for radiology residents, nuclear medicine residents and fellows, nuclear medicine specialists, and nuclear medicine technicians. Known for its clear and easily understood writing style, superb illustrations, and self-assessment features, this updated classic is an ideal reference for all diagnostic imaging and therapeutic patient care related to nuclear medicine, as well as an excellent review tool for certification or MOC preparation. - Provides comprehensive, clear explanations of everything from principles of human physiology, pathology, physics, radioactivity, radiopharmaceuticals, radiation safety, and legal requirements to hot topics such as new brain and neuroendocrine tumor agents and hybrid imaging, including PET/MR and PET/CT. - Covers the imaging of every body system, as well as inflammation, infection and tumor imaging; pearls and pitfalls for every chapter; and pediatric doses and guidelines in compliance with the Image Gently and Image Wisely programs. - Features a separate self-assessment section on differential diagnoses, imaging procedures and artifacts, and safety issues with unknown cases, questions, answers, and explanations. - Includes new images and illustrations, for a total of 430 high-quality, multi-modality examples throughout the text. - Reflects recent advances in the field, including updated nuclear medicine imaging and therapy guidelines • Updated dosimetry values and effective doses for all radiopharmaceuticals with new values from the 2015 International Commission on Radiological Protection • Updated information regarding advances in brain imaging, including amyloid, dopamine transporter and dementia imaging • Inclusion of Ga-68 DOTA PET/CT for neuroendocrine tumors • Expanded information on correlative and hybrid imaging with SPECT/CT • New myocardial agents • and more. - Contains extensive appendices including updated comprehensive imaging protocols for routine and hybrid imaging, pregnancy and breastfeeding guidelines, pediatric dosages, non-radioactive pharmaceuticals used in interventional and cardiac stress imaging, and radioactivity conversion tables.




Basic Science of PET Imaging


Book Description

This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.







Nuclear Medicine Physics: The Basics


Book Description

Part of the renowned The Basics series, Nuclear Medicine Physics helps build foundational knowledge of how and why things happen in the clinical environment. Ideal for board review and reference, the 8th edition provides a practical summary of this complex field, focusing on essential details as well as real-life examples taken from nuclear medicine practice. New full-color illustrations, concise text, essential mathematical equations, key points, review questions, and useful appendices help you quickly master challenging concepts in nuclear medicine physics.




Physics in Nuclear Medicine


Book Description

In this work, the authors provide up-to-date, comprehensive information on the physics underlying modern nuclear medicine and imaging using radioactively labelled tracers. Examples are presented with solutions worked out in step-by-step detail, illustrating important concepts and calculations.




Nuclear Medicine and PET/CT - E-Book


Book Description

A comprehensive guide to procedures and technologies, Nuclear Medicine and PET/CT: Technology and Techniques provides a single source for state-of-the-art information on all aspects of nuclear medicine. Coverage includes relevant anatomy and physiology and discusses each procedure in relation to the specific use of radiopharmaceuticals and the instruments required. Edited by experts in nuclear imaging and PET/CT, Paul E. Christian and Kristen M. Waterstram-Rich, this edition has a new chapter on MRI as it relates to nuclear medicine and includes practical, step-by-step instructions for procedures. PET/CT focus with hybrid PET/CT studies in several chapters provides cutting-edge information that is especially beneficial to working technologists. CT Physics and Instrumentation chapter introduces CT as it is applied to PET imaging for combined PET/CT studies. Authoritative, comprehensive resource conveys state-of-the-art information, eliminating the need to search for information in other sources. Foundation chapters cover basic math, statistics, physics, instrumentation, computers, lab science, radiochemistry, and pharmacology, allowing you to understand how and why procedures are performed. Accessible writing style and approach to basic science subjects simplifies topics, progressing from fundamentals to more complex concepts. More than 50 practice problems in the math and statistics chapter let you brush up on basic math skills, with answers provided in the back of the book. Key terms, chapter outlines, learning objectives, and suggested readings help you organize your study. A table of radionuclides used in nuclear medicine and PET is provided in the appendix for quick reference. A glossary provides definitions of key terms and important concepts. High-profile editors and contributors come from a variety of educational and clinical settings, providing a broad philosophic and geographic perspective. New MRI Physics, Instrumentation and Clinical Introduction chapter provides important background on MRI and its relationship with nuclear medicine. Procedures boxes in body systems chapters provide step-by-step descriptions of clinical procedures. Updates and revisions keep you current with the latest advances. Expanded 16-page color insert includes more diagnostic images demonstrating realistic scans found in practice.