Inflammation: Natural Resources and Its Applications


Book Description

Inflammation is the very natural process of our body; it does its work immediately and smoothly along with lots of helpers. Inflammation is linked to immune system as acute inflammatory or pro-inflammatory phase through macrophage activation. This book is for researchers and scholars in the field of life sciences and medical sciences. The book contains all inflammatory sources around the world. It emphasizes on anti-inflammatory sources along with its active inflammatory constituents and other medicinal uses with authentic references. Anti-inflammation is a kind of activity with is found in nearly all of the natural sources used for major biological activities. So, the book helps them to correlate their activity of interest with anti-inflammatory source. The present work deals with illustrative representation of inflammation, causes of inflammation, inflammatory mediators, anti-inflammatory sources other uses and inflammation and lifestyle. It mainly provides the researchers the updated information from the ancient to the most recent ongoing research on inflammation. This book imparts pace to their idea of thinking, assist to make clear predictions before proceeding to research. The introduction includes natural sources of inflammation and its benefits; the sources are from plant, animal and marine. The book tells how these sources are useful for us to cure several diseases and opens new path for further research. Inflammation part of the book is well presented along with its phases, types and other diseases interrelated with inflammation. Inflammatory mediators, the foremost player of inflammation are defined in a very pleasant and convenient manner. The chapter includes both cell- derived and plasma - derived mediators illustratively with their synthesis and action. Natural source of anti-inflammation is the heart chapter of this book which contains all anti-inflammation sources from plants, marine and animals. This chapter also contains short description of most of the sources, its availability and uses. The authors have also added inflammatory models for assessment of biological activities of natural sources both in vitro and in vivo. Inflammation free lifestyle is described very nicely in the book. The contents are very specific and relevant to its topic; all the data provided is unique and useful. The anti-inflammatory table includes sources, plant parts used, active constituents and other uses. This data provides ample information regarding anti-inflammatory research and innovation. The highlights of this book shall be: -Describes almost all anti-inflammatory sources around the globe at one place in a more convenient tabulated form -Illustrative representation makes the book more attractive and interactive




Antifouling Compounds


Book Description

Awareness of the dangers of toxic components in antifouling coatings has raised interest in the potential for nontoxic alternatives. Marine organisms from bacteria to invertebrates and plants use chemicals to communicate and defend themselves. This book explores natural based antifoulants, their ecological functions, methods of characterisation and possible uses in antifouling. The text takes on the challenge of identifying such compounds, designing sustainable production and incorporating them into antifouling coatings.




Handbook of Anticancer Drugs from Marine Origin


Book Description

This timely desk reference focuses on marine-derived bioactive substances which have biological, medical and industrial applications. The medicinal value of these marine natural products are assessed and discussed. Their function as a new and important resource in novel, anticancer drug discovery research is also presented in international contributions from several research groups. For example, the potential role of Spongistatin, Apratoxin A, Eribulin mesylate, phlorotannins, fucoidan, as anticancer agents is explained. The mechanism of action of bioactive compounds present in marine algae, bacteria, fungus, sponges, seaweeds and other marine animals and plants are illustrated via several mechanisms. In addition, this handbook lists various compounds that are active candidates in chemoprevention and their target actions. The handbook also places into context the demand for anticancer nutraceuticals and their use as potential anti-cancer pharmaceuticals and medicines. This study of advanced and future types of natural compounds from marine sources is written to facilitate the understanding of Biotechnology and its application to marine natural product drug discovery research.




Advances in Marine Antifouling Coatings and Technologies


Book Description

Marine biofouling can be defined as the undesirable accumulation of microorganisms, algae and animals on structures submerged in seawater. From the dawn of navigation, marine biofouling has been a major problem for shipping in such areas as reduced speed, higher fuel consumption and increased corrosion. It also affects industries using off-shore structures such as oil and gas production and aquaculture. Growing concerns about the environmental impact of antifouling coatings has led to major new research to develop more environmentally-friendly alternatives. Advances in marine antifouling coatings and technologies summaries this wealth of research and its practical implications. This book is divided into four sub-sections which discuss: marine fouling organisms and their impact, testing and development of antifouling coatings, developments in chemically-active marine antifouling technologies, and new surface approaches to the control of marine biofouling. It provides an authoritative overview of the recent advances in understanding the biology of fouling organisms, the latest developments on antifouling screening techniques both in the field and in the laboratory, research on safer active compounds and the progress on nontoxic coatings with tailor-made surface properties. With its distinguished editors and international team of contributors, Advances in marine antifouling coatings and technologies is a standard reference for manufacturers of marine antifouling solutions, the shipping industry, oil and gas producers, aquaculture and other industries using offshore structures, and academics researching this important area. Assesses marine antifouling organisms and their impact, including a historical review and directions for future research Discusses developments in antifouling coatings examining chemically-active and new surface approaches Reviews the environmentally friendly alternative of safer active compounds and the progress of non-toxic compounds




Annual Plant Reviews, Functions and Biotechnology of Plant Secondary Metabolites


Book Description

This important volume commences with an overview of the modes of action of defensive secondary metabolites, followed by detailed surveys of chemical defense in marine ecosystems, the biochemistry of induced defense, plant-microbe interactions and medical applications. A chapter is also included covering biotechnological aspects of producing valuable secondary metabolites in plant cell and organ cultures. This is a comprehensive and fully updated new edition, edited by Professor Michael Wink and including contributions from many internationally acknowledged experts in the field.




Modern NMR Approaches to the Structure Elucidation of Natural Products


Book Description

The Ghanian plant Cryptolepis sanguinolenta is the source of a series of fascinating indoloquinoline alkaloids. The most unusual member of this alkaloid series was initially proposed to be a spiro nonacyclic structure, named cryptospirolepine, and was elucidated in 1993 based on the technologies available at that time. There were, however, several annoying attributes to the structure that bothered analysts for the ensuing 22 years. During the two decades that followed the initial work there have been enormous developments in NMR technology. Using new experimental approaches, specifically homodecoupled 1,1- and 1,n-HD-ADEQUATE NMR experiments developed in 2014, the structure of only a 700 µg sample of cryptospirolepine has been revised and is shown on the cover of this volume. The confluence of the NMR technological and methodological advances that allowed the revision of the structure of cryptospirolepine using a submilligram sample seems a fitting example for this book, which is dedicated to the NMR characterization of various classes of natural products. Volume 2 considers data processing and algorithmic based analyses tailored to natural product structure elucidation and reviews the application of NMR to the analysis of a series of different natural product families including marine natural products, terpenes, steroids, alkaloids and carbohydrates. Volume 1 discusses contemporary NMR approaches including optimized and future hardware and experimental approaches to obtain both the highest quality and most appropriate spectral data for analysis. These books, bringing together acknowledged experts, uniquely focus on the combination of experimental approaches and modern hardware and software applied to the structure elucidation of natural products. The volumes will be an essential resource for NMR spectroscopists, natural product chemists and industrial researchers working on natural product analysis or the characterization of impurities and degradation products of pharmaceuticals that can be as scarce as natural product samples.




Algal Toxins in Seafood and Drinking Water


Book Description

Some taxonomic and biologic aspects of toxic dinoflagellates / Karen A. Steidinger -- Methods of analysis for algal toxins: dinoflagellate and diatom toxins / John J. Sullivan -- Mode of action of toxins of seafood poisoning / Daniel G. Baden, Vera L. Trainer -- Paralytic shellfish poisoning / C.Y. Kao -- Diarrhetic shellfish poisoning / Tore Aune, Magne Yndestad -- Ciguatera fish poisoning / Raymond Bagnis -- Control measures in shellfish and finfish industries in the USA / James Hungerford, Marleen Wekell -- Seafood toxins of algal origin and their control in Canada / A.D. Cembella, E. Todd -- Taxonomy of toxic cyanophyceae (Cyanobacteria) / Olav M. Skulberg [and others] -- Measurement of toxins from blue-green algae in water and foodstuffs / Ian R. Falconer -- Mechanism of toxicity of cyclic peptide toxins from blue-green algae / Ian R. Falconer -- Diseases related to freshwater blue-green algal toxins and control measures / Wayne W. Carmichael, Ian R. Falconer.




Microalgae in Health and Disease Prevention


Book Description

Microalgae in Health and Disease Prevention is a comprehensive reference that addresses the historical and potential use of microalgae, its extracts, secondary metabolites, and molecular constituents for enhancing human health and preventing diseases. Each chapter features an overview, and the book includes coverage of microalgae biology, harmful algae, the use of microalgae in alcohol and food, and as sources of macronutrients, micronutrients, vitamins, and minerals. The historical use of microalgae, in addition to its potential use as a nutraceutical and cosmeceutical, is also addressed. The book provides coverage of relevant, up-to-date research as assembled by a group of contributors who are dedicated to the advancement of microalgae use in health, diet and nutrition. Discusses research findings on the relationship between microalgal diet, nutrition and human health Presents the medicinal, anti-allergic and psychoactive properties of microalgae Identifies toxic and harmful microalgae Addresses microalgal lipids, proteins and carbohydrates




Trends in Neuroergonomics: A Comprehensive Overview


Book Description

This Research Topic is dedicated to Raja Parasuraman who unexpectedly passed on March 22nd 2015. Raja Parasuraman’s pioneering work led the emergence of Neuroergonomics as a new scientific field. He combined his research interests in the field of Neuroergonomics which he defined as the study of the human brain in relation to performance at work and everyday settings. Raja Parasuraman was a pioneer, a truly exceptional researcher and an extraordinary person. He made significant contributions to a number of disciplines, from human factors to cognitive neuroscience. His advice to young researchers was to be passionate in order to develop theory and knowledge that can guide the design of technologies and environments for people. His legacy, the field of Neuroergonomics, will live on in countless faculties and students whom he advised and inspired with unmatched humility throughout the whole of his distinguished career. Raja Parasuraman was an impressive human being, a very kind person, and an absolutely inspiring individual who will be remembered by everyone who had the chance to meet him. About this Research Topic Since the advent of neuroergonomics, significant progress has been made with respect to methodology and tools for the investigation of the brain and behavior at work. This is especially the case for neuroscientific methods where the availability of ambulatory hardware, wearable sensors and advanced data analyses allow for imaging of brain dynamics in humans in applied environments. Methods such as: electroencephalography (EEG), functional near-infrared spectroscopy (fNIRS), and stimulation approaches like transcranial direct-currrent stimulation (tDCS) have made significant progress in both recording and altering brain activity while allowing full body movements outside laboratory environments. For neuroergonomics, the application of brain imaging in real-world scenarios is highly relevant. Traditionally, brain imaging experiments in human factors research tend to avoid active behavior for fear of artifacts and a contaminated data set that would provide limited insight into brain dynamics in real working environments. To overcome these problems new analyses approaches have to be developed that identify artifacts resulting from hostile recording environments and movement-related non-brain activity stemming from eye-, head, and full-body movements. The application of methodology from the field of Brain-Computer Interfacing (BCI) for neuroergonomics is one approach that has significant potential to enhance ambulatory monitoring and applied testing. Passive BCIs allow for assessing aspects of the user state online, such that systems can automatically adapt to their user. This neuroadaptive technology could lead to highly efficient working environments, to auto-adaptive experimental paradigms and to a continuous tracking of cognitive and affective aspects of the user state. Hence, deployment of portable neuroimaging technologies to real time settings could help assess cognitive and motivational states of personnel assigned to perform critical tasks. This Research Topic gathers submissions that cover new approaches in neuroergonomics. Different article type cover advanced neuroscience methods and neuroergonomics techniques as well as analysis approaches to investigate brain dynamics in working environments. The selection of papers provides insights into new neuroergonomic research approaches that demonstrate significant advances in brain imaging technologies that become more and more mobile, Moreover, a strong trend for new analyses approaches and paradigms investigating real work settings can be seen. Together, this unique collection of latest research papers provides a comprehensive overview on the latest developments in neuroergonomics.